Ensembl ID ENSG00000124802 Gene ID 9521 Accession 3212
Gene Symbol EEF1E1 Alias P18;AIMP3 Full Name eukaryotic translation elongation factor 1 epsilon 1
Position 6 : 8073360 - 8102559 Length 29200 bases Strand Minus strand
Status Confidence Main interacting RNAstRNARBP type Non-canonical_RBPs
Summary This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2. [provided by RefSeq, Dec 2010]

ENSG00000124802 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000124802 EEF1E1 -0.5 2.23e-16 KIRC
ENSG00000124802 EEF1E1 0.93 2.71e-11 BLCA
ENSG00000124802 EEF1E1 0.62 4.94e-25 BRCA
ENSG00000124802 EEF1E1 1.11 1.42e-28 COAD
ENSG00000124802 EEF1E1 -1.2 1.39e-23 KICH
ENSG00000124802 EEF1E1 0.79 6.82e-18 LUSC
ENSG00000124802 EEF1E1 0.53 4.95e-13 PRAD
ENSG00000124802 EEF1E1 0.86 1.61e-13 UCEC
ENSG00000124802 EEF1E1 0.78 7.98e-18 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000124802 EEF1E1 tumor 16849534
ENSG00000124802 EEF1E1 tumor 18343821
ENSG00000124802 EEF1E1 tumor 20726853
ENSG00000124802 EEF1E1 gastric cancer 21789020
ENSG00000124802 EEF1E1 tumor 22106287
ENSG00000124802 EEF1E1 bladder cancer 24917520
ENSG00000124802 EEF1E1 tumor 25465621
ENSG00000124802 EEF1E1 Bladder Cancer 26382821
ENSG00000124802 EEF1E1 tumour 27781386
ENSG00000124802 EEF1E1 tumor 28797100
ENSG00000124802 EEF1E1 tumor 29342219
ENSG00000124802 EEF1E1 cancer 30250065
ENSG00000124802 EEF1E1 tumour 30302025
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000124802 EEF1E1 SARC 0.00051 high
ENSG00000124802 EEF1E1 CHOL 0.028 low
ENSG00000124802 EEF1E1 UVM 0.018 low
ENSG00000124802 EEF1E1 UCEC 0.017 high
ENSG00000124802 EEF1E1 ACC 0.021 high
ENSG00000124802 EEF1E1 LGG 0.0033 low
ENSG00000124802 EEF1E1 LUSC 0.034 low
ENSG00000124802 EEF1E1 HNSC 0.027 high
ENSG00000124802 EEF1E1 KIRP 0.028 high
ENSG00000124802 EEF1E1 KICH 0.0044 high
ENSG00000124802 EEF1E1 BRCA 0.0068 high
ENSG00000124802 EEF1E1 ESCA 0.044 high
ENSG00000124802 EEF1E1 OV 0.0013 low
ENSG00000124802 EEF1E1 DLBC 0.029 low
ENSG00000124802 EEF1E1 KIRC 0.0025 high
ENSG00000124802 EEF1E1 GBM 0.0071 high
ENSG00000124802 EEF1E1 SKCM 0.017 low
ENSG00000124802 EEF1E1 CESC 0.00056 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000124802 EEF1E1 LUSC Del 1.656840 0.078876 0.347241 0.265469
ENSG00000124802 EEF1E1 LUAD Amp 0.655235 0.115344 0.435081 0.381783
ENSG00000124802 EEF1E1 CESC Del 0.765335 0.068262 0.533275 0.142373
ENSG00000124802 EEF1E1 THYM Del 1.199597 0.053692 0.410541 0.211382
ENSG00000124802 EEF1E1 SARC Del 0.926029 0.128064 0.519131 0.315175
ENSG00000124802 EEF1E1 PAAD Del 2.605704 0.080610 0.353548 0.402174
ENSG00000124802 EEF1E1 ESCA Del 6.221726 0.220060 0.447208 0.336957
ENSG00000124802 EEF1E1 SKCM Amp 7.635369 0.304020 0.784330 0.572207
ENSG00000124802 EEF1E1 HNSC Del 1.213032 0.060355 0.374270 0.180077
ENSG00000124802 EEF1E1 LIHC Amp 2.761311 0.163066 0.752856 0.416216
ENSG00000124802 EEF1E1 BLCA Amp 3.855753 0.261944 0.502063 0.328431
ENSG00000124802 EEF1E1 STAD Del 4.757994 0.106301 0.414110 0.188209
ENSG00000124802 EEF1E1 UVM Amp 3.933817 0.347476 1.177782 0.562500
ENSG00000124802 EEF1E1 OV Amp 6.894087 0.489704 0.768821 0.483592