Ensembl ID ENSG00000124789 Gene ID 9972 Accession 8062
Gene Symbol NUP153 Alias N153;HNUP153 Full Name nucleoporin 153
Position 6 : 17615035 - 17706925 Length 91891 bases Strand Minus strand
Status Confidence Main interacting RNAsdiverseRBP type Canonical_RBPs
Summary Nuclear pore complexes regulate the transport of macromolecules between the nucleus and cytoplasm. They are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are glycoproteins found in nuclear pores and contain characteristic pentapeptide XFXFG repeats as well as O-linked N-acetylglucosamine residues oriented towards the cytoplasm. The protein encoded by this gene has three distinct domains: a N-terminal region containing a pore targeting and an RNA-binding domain domain, a central region containing multiple zinc finger motifs, and a C-terminal region containing multiple XFXFG repeats. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]

ENSG00000124789 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000124789 NUP153 tumor 20561986
ENSG00000124789 NUP153 cancers 22249246
ENSG00000124789 NUP153 pancreatic cancer 24041470
ENSG00000124789 NUP153 cancer 26221075
ENSG00000124789 NUP153 colorectal cancer 30347601
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000124789 NUP153 UCEC 0.008 high
ENSG00000124789 NUP153 THCA 0.028 high
ENSG00000124789 NUP153 HNSC 0.007 low
ENSG00000124789 NUP153 READ 0.00056 low
ENSG00000124789 NUP153 KIRP 0.00025 high
ENSG00000124789 NUP153 KICH 0.0032 high
ENSG00000124789 NUP153 PCPG 0.0074 low
ENSG00000124789 NUP153 THYM 0.026 low
ENSG00000124789 NUP153 OV 0.011 low
ENSG00000124789 NUP153 PRAD 0.04 high
ENSG00000124789 NUP153 BLCA 0.034 high
ENSG00000124789 NUP153 LAML 0.008 low
ENSG00000124789 NUP153 SKCM 0.011 high
ENSG00000124789 NUP153 CESC 0.023 low
ENSG00000124789 NUP153 LIHC 0.032 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000124789 NUP153 SARC Del 0.964392 0.129328 0.538241 0.295720
ENSG00000124789 NUP153 PAAD Del 1.963432 0.070608 0.345696 0.391304
ENSG00000124789 NUP153 ESCA Del 2.950582 0.156514 0.422958 0.309783
ENSG00000124789 NUP153 SKCM Amp 5.353788 0.251582 0.763081 0.564033
ENSG00000124789 NUP153 LIHC Amp 2.824561 0.164341 0.750589 0.421622
ENSG00000124789 NUP153 BLCA Amp 12.756032 0.439555 0.667088 0.362745
ENSG00000124789 NUP153 BRCA Amp 1.985660 0.169892 0.571016 0.269444
ENSG00000124789 NUP153 STAD Del 1.448547 0.071440 0.376635 0.158730
ENSG00000124789 NUP153 UVM Amp 5.108221 0.407116 1.220161 0.562500
ENSG00000124789 NUP153 OV Amp 10.944672 0.563023 0.791883 0.516408