Ensembl ID
ENSG00000124789
Gene ID
9972
Accession
8062
Gene Symbol
NUP153
Alias
N153;HNUP153
Full Name
nucleoporin 153
Position
6 : 17615035 - 17706925
Length
91891 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs diverse RBP type
Canonical_RBPs
Summary
Nuclear pore complexes regulate the transport of macromolecules between the nucleus and cytoplasm. They are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are glycoproteins found in nuclear pores and contain characteristic pentapeptide XFXFG repeats as well as O-linked N-acetylglucosamine residues oriented towards the cytoplasm. The protein encoded by this gene has three distinct domains: a N-terminal region containing a pore targeting and an RNA-binding domain domain, a central region containing multiple zinc finger motifs, and a C-terminal region containing multiple XFXFG repeats. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
ENSG00000124789 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000124789
NUP153
tumor
20561986
ENSG00000124789
NUP153
cancers
22249246
ENSG00000124789
NUP153
pancreatic cancer
24041470
ENSG00000124789
NUP153
cancer
26221075
ENSG00000124789
NUP153
colorectal cancer
30347601
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000124789
NUP153
UCEC
0.008
high
show
ENSG00000124789
NUP153
THCA
0.028
high
show
ENSG00000124789
NUP153
HNSC
0.007
low
show
ENSG00000124789
NUP153
READ
0.00056
low
show
ENSG00000124789
NUP153
KIRP
0.00025
high
show
ENSG00000124789
NUP153
KICH
0.0032
high
show
ENSG00000124789
NUP153
PCPG
0.0074
low
show
ENSG00000124789
NUP153
THYM
0.026
low
show
ENSG00000124789
NUP153
OV
0.011
low
show
ENSG00000124789
NUP153
PRAD
0.04
high
show
ENSG00000124789
NUP153
BLCA
0.034
high
show
ENSG00000124789
NUP153
LAML
0.008
low
show
ENSG00000124789
NUP153
SKCM
0.011
high
show
ENSG00000124789
NUP153
CESC
0.023
low
show
ENSG00000124789
NUP153
LIHC
0.032
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000124789
NUP153
SARC
Del
0.964392
0.129328
0.538241
0.295720
ENSG00000124789
NUP153
PAAD
Del
1.963432
0.070608
0.345696
0.391304
ENSG00000124789
NUP153
ESCA
Del
2.950582
0.156514
0.422958
0.309783
ENSG00000124789
NUP153
SKCM
Amp
5.353788
0.251582
0.763081
0.564033
ENSG00000124789
NUP153
LIHC
Amp
2.824561
0.164341
0.750589
0.421622
ENSG00000124789
NUP153
BLCA
Amp
12.756032
0.439555
0.667088
0.362745
ENSG00000124789
NUP153
BRCA
Amp
1.985660
0.169892
0.571016
0.269444
ENSG00000124789
NUP153
STAD
Del
1.448547
0.071440
0.376635
0.158730
ENSG00000124789
NUP153
UVM
Amp
5.108221
0.407116
1.220161
0.562500
ENSG00000124789
NUP153
OV
Amp
10.944672
0.563023
0.791883
0.516408
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