Ensembl ID ENSG00000124782 Gene ID 6239 Accession 10449
Gene Symbol RREB1 Alias HNT;FINB;LZ321;Zep-1;RREB-1 Full Name ras responsive element binding protein 1
Position 6 : 7107597 - 7251980 Length 144384 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary The protein encoded by this gene is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

ENSG00000124782 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000124782 RREB1 bladder cancer 17496927
ENSG00000124782 RREB1 prostate cancer 17550981
ENSG00000124782 RREB1 tumours 19404853
ENSG00000124782 RREB1 tumour 19558368
ENSG00000124782 RREB1 prostate cancer 19802870
ENSG00000124782 RREB1 prostate cancer 21360563
ENSG00000124782 RREB1 tumor 21613827
ENSG00000124782 RREB1 cancer 21622730
ENSG00000124782 RREB1 cancer 21703425
ENSG00000124782 RREB1 pancreatic cancer 22751122
ENSG00000124782 RREB1 tumors 24040120
ENSG00000124782 RREB1 pancreatic cancer 24195024
ENSG00000124782 RREB1 tumor 24418439
ENSG00000124782 RREB1 pancreatic cancer 25050557
ENSG00000124782 RREB1 cervical cancer 26252302
ENSG00000124782 RREB1 cancer 26462467
ENSG00000124782 RREB1 tumor 27462774
ENSG00000124782 RREB1 pancreatic cancer 27835861
ENSG00000124782 RREB1 cancer 28956004
ENSG00000124782 RREB1 tumors 29388632
ENSG00000124782 RREB1 tumor 29760388
ENSG00000124782 RREB1 tumor 30018527
ENSG00000124782 RREB1 DLBCL 30355676
ENSG00000124782 RREB1 pancreatic cancer 30814490
ENSG00000124782 RREB1 tumors 30982491
ENSG00000124782 RREB1 tumor 31346320
ENSG00000124782 RREB1 tumour 31915377
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000124782 RREB1 MESO 0.036 low
ENSG00000124782 RREB1 SARC 0.039 high
ENSG00000124782 RREB1 STAD 7e-04 low
ENSG00000124782 RREB1 PAAD 0.037 high
ENSG00000124782 RREB1 UCEC 0.045 low
ENSG00000124782 RREB1 HNSC 0.0012 low
ENSG00000124782 RREB1 READ 0.0093 low
ENSG00000124782 RREB1 KIRP 0.0014 low
ENSG00000124782 RREB1 LUAD 0.01 high
ENSG00000124782 RREB1 ESCA 0.041 low
ENSG00000124782 RREB1 KIRC 0.00073 low
ENSG00000124782 RREB1 PRAD 0.033 low
ENSG00000124782 RREB1 LAML 0.014 low
ENSG00000124782 RREB1 CESC 0.021 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000124782 RREB1 LUSC Del 1.651769 0.078876 0.353114 0.261477
ENSG00000124782 RREB1 THYM Del 1.425662 0.058974 0.403553 0.211382
ENSG00000124782 RREB1 SARC Del 1.009805 0.131013 0.523679 0.319066
ENSG00000124782 RREB1 PAAD Del 2.948902 0.085906 0.357459 0.402174
ENSG00000124782 RREB1 ESCA Del 6.765208 0.229475 0.447894 0.336957
ENSG00000124782 RREB1 SKCM Amp 7.786977 0.308285 0.784742 0.572207
ENSG00000124782 RREB1 HNSC Del 0.757758 0.054962 0.372363 0.176245
ENSG00000124782 RREB1 LIHC Amp 2.957354 0.167096 0.761096 0.413514
ENSG00000124782 RREB1 BLCA Amp 4.989365 0.289117 0.539419 0.325980
ENSG00000124782 RREB1 BRCA Del 2.488166 0.078091 0.428458 0.168519
ENSG00000124782 RREB1 STAD Del 4.438113 0.103601 0.401420 0.185941
ENSG00000124782 RREB1 PRAD Del 0.976304 0.075697 0.486466 0.093496
ENSG00000124782 RREB1 UCEC Amp 0.874150 0.107524 0.559621 0.189239
ENSG00000124782 RREB1 UVM Amp 5.139661 0.410285 1.204233 0.562500
ENSG00000124782 RREB1 OV Amp 8.474849 0.519732 0.791406 0.485320