Ensembl ID ENSG00000124701 Gene ID 10930 Accession 605
Gene Symbol APOBEC2 Alias ARP1;ARCD1 Full Name apolipoprotein B mRNA editing enzyme catalytic subunit 2
Position 6 : 41053202 - 41064891 Length 11690 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary Enables cytidine deaminase activity and identical protein binding activity. Involved in DNA demethylation. Acts upstream of or within cytidine to uridine editing. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ENSG00000124701 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000124701 APOBEC2 -3.3 4.64e-13 HNSC
ENSG00000124701 APOBEC2 -1.6 7.86e-11 LUSC
ENSG00000124701 APOBEC2 -3.6 8.27e-14 ESCA
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000124701 APOBEC2 tumour 16427049
ENSG00000124701 APOBEC2 lung tumors 21469143
ENSG00000124701 APOBEC2 breast cancers 26682542
ENSG00000124701 APOBEC2 tumor 27111033
ENSG00000124701 APOBEC2 ovarian cancer 27527602
ENSG00000124701 APOBEC2 tumours 31340720
ENSG00000124701 APOBEC2 liver cancer 31485598
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000124701 APOBEC2 SARC 0.018 high
ENSG00000124701 APOBEC2 THCA 0.0011 low
ENSG00000124701 APOBEC2 ACC 0.0017 high
ENSG00000124701 APOBEC2 HNSC 0.0093 high
ENSG00000124701 APOBEC2 READ 0.0046 low
ENSG00000124701 APOBEC2 KIRP 0.0052 low
ENSG00000124701 APOBEC2 LUAD 0.0078 low
ENSG00000124701 APOBEC2 BRCA 0.04 low
ENSG00000124701 APOBEC2 ESCA 0.019 high
ENSG00000124701 APOBEC2 OV 0.032 low
ENSG00000124701 APOBEC2 GBM 0.037 low
ENSG00000124701 APOBEC2 SKCM 0.037 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000124701 APOBEC2 LUAD Amp 1.752167 0.143949 0.501968 0.364341
ENSG00000124701 APOBEC2 COAD Amp 1.342919 0.080627 0.532886 0.212860
ENSG00000124701 APOBEC2 ESCA Amp 3.771394 0.423979 0.811724 0.320652
ENSG00000124701 APOBEC2 STAD Amp 5.751553 0.252506 0.655976 0.253968
ENSG00000124701 APOBEC2 UVM Amp 0.758988 0.170641 1.117163 0.525000