Ensembl ID ENSG00000124374 Gene ID 400961 Accession 29200
Gene Symbol PAIP2B Alias NA Full Name poly(A) binding protein interacting protein 2B
Position 2 : 71182738 - 71227103 Length 44366 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary Most mRNAs, except for histones, contain a 3-prime poly(A) tail. Poly(A)-binding protein (PABP; see MIM 604679) enhances translation by circularizing mRNA through its interaction with the translation initiation factor EIF4G1 (MIM 600495) and the poly(A) tail. Various PABP-binding proteins regulate PABP activity, including PAIP1 (MIM 605184), a translational stimulator, and PAIP2A (MIM 605604) and PAIP2B, translational inhibitors (Derry et al., 2006 [PubMed 17381337]).[supplied by OMIM, Mar 2008]

ENSG00000124374 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000124374 PAIP2B -2.0 1.99e-46 HNSC
ENSG00000124374 PAIP2B -0.6 4.74e-13 BRCA
ENSG00000124374 PAIP2B -1.6 6.96e-13 STAD
ENSG00000124374 PAIP2B -3.2 9.25e-22 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000124374 PAIP2B pancreatic tumors 28470677
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000124374 PAIP2B SARC 0.042 high
ENSG00000124374 PAIP2B STAD 0.0095 high
ENSG00000124374 PAIP2B CHOL 0.011 high
ENSG00000124374 PAIP2B PAAD 0.046 low
ENSG00000124374 PAIP2B UCEC 0.00014 high
ENSG00000124374 PAIP2B THCA 0.0046 high
ENSG00000124374 PAIP2B LGG 0.0012 low
ENSG00000124374 PAIP2B LUSC 0.034 high
ENSG00000124374 PAIP2B KIRP 0.0021 low
ENSG00000124374 PAIP2B LUAD 0.00013 low
ENSG00000124374 PAIP2B PCPG 0.047 high
ENSG00000124374 PAIP2B THYM 0.0036 high
ENSG00000124374 PAIP2B COAD 0.041 high
ENSG00000124374 PAIP2B BLCA 0.039 high
ENSG00000124374 PAIP2B LIHC 0.015 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency