Ensembl ID ENSG00000124279 Gene ID 79072 Accession 28758
Gene Symbol FASTKD3 Alias NA Full Name FAST kinase domains 3
Position 5 : 7859159 - 7869037 Length 9879 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes a member of a small family of Fas-activated serine/threonine kinase domain (FASTKD) containing proteins that share an amino terminal mitochondrial targeting domain and multiple carboxy terminal FAST domains as well as a putative RNA-binding RAP domain. The members of this family are ubiquitously expressed and are generally most abundant in mitochondria-enriched tissues such as heart, skeletal muscle and brown-adipose tissue. Some members of this protein family may play a role in apoptosis. The protein encoded by this gene interacts with components of the mitochondrial respiratory and translation networks. A pseudogene of this gene is also present on chromosome 5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

ENSG00000124279 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000124279 FASTKD3 0.57 2.55e-16 KIRC
ENSG00000124279 FASTKD3 0.97 1.04e-12 BLCA
ENSG00000124279 FASTKD3 0.55 2.66e-30 BRCA
ENSG00000124279 FASTKD3 0.97 2.68e-26 LUSC
ENSG00000124279 FASTKD3 0.88 2.59e-24 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000124279 FASTKD3 SARC 0.033 high
ENSG00000124279 FASTKD3 STAD 0.0086 low
ENSG00000124279 FASTKD3 UVM 0.041 high
ENSG00000124279 FASTKD3 PAAD 0.016 low
ENSG00000124279 FASTKD3 UCEC 0.0039 high
ENSG00000124279 FASTKD3 ACC 0.041 low
ENSG00000124279 FASTKD3 LGG 0.00018 high
ENSG00000124279 FASTKD3 HNSC 0.0079 low
ENSG00000124279 FASTKD3 READ 0.0045 low
ENSG00000124279 FASTKD3 KIRP 0.013 high
ENSG00000124279 FASTKD3 KICH 0.011 high
ENSG00000124279 FASTKD3 LUAD 0.00064 low
ENSG00000124279 FASTKD3 PCPG 0.028 high
ENSG00000124279 FASTKD3 THYM 0.028 low
ENSG00000124279 FASTKD3 BRCA 0.0022 high
ENSG00000124279 FASTKD3 OV 0.0021 low
ENSG00000124279 FASTKD3 PRAD 0.0025 high
ENSG00000124279 FASTKD3 BLCA 0.0028 low
ENSG00000124279 FASTKD3 SKCM 0.0022 low
ENSG00000124279 FASTKD3 CESC 0.0098 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000124279 FASTKD3 LUSC Amp 13.316576 0.451287 0.867316 0.768463
ENSG00000124279 FASTKD3 LUAD Amp 13.393987 0.319309 0.747445 0.627907
ENSG00000124279 FASTKD3 LGG Del 1.232776 0.044952 0.488075 0.085770
ENSG00000124279 FASTKD3 CESC Amp 1.834754 0.173358 0.953542 0.454237
ENSG00000124279 FASTKD3 SKCM Amp 1.866754 0.157708 0.681114 0.245232
ENSG00000124279 FASTKD3 SKCM Del 1.869959 0.084665 0.460300 0.215259
ENSG00000124279 FASTKD3 HNSC Amp 0.750682 0.116856 0.647207 0.454023
ENSG00000124279 FASTKD3 BLCA Amp 2.991156 0.238998 0.795762 0.504902
ENSG00000124279 FASTKD3 UCEC Amp 0.986231 0.110417 0.784897 0.148423
ENSG00000124279 FASTKD3 OV Amp 3.627381 0.419140 0.883433 0.506045