Ensembl ID ENSG00000123297 Gene ID 10102 Accession 12367
Gene Symbol TSFM Alias EFTS;EFTSMT Full Name Ts translation elongation factor, mitochondrial
Position 12 : 57782761 - 57808071 Length 25311 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes a mitochondrial translation elongation factor. The encoded protein is an enzyme that catalyzes the exchange of guanine nucleotides on the translation elongation factor Tu during the elongation step of mitchondrial protein translation. Mutations in this gene are associated with combined oxidative phosphorylation deficiency-3 syndrome. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2010]

ENSG00000123297 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000123297 TSFM -0.4 3.28e-14 KIRC
ENSG00000123297 TSFM 0.64 5.76e-29 BRCA
ENSG00000123297 TSFM 0.61 4.28e-13 KICH
ENSG00000123297 TSFM 0.87 3.17e-31 LUSC
ENSG00000123297 TSFM 0.70 8.23e-16 UCEC
ENSG00000123297 TSFM 0.88 1.08e-19 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000123297 TSFM tumors 14871979
ENSG00000123297 TSFM tumors 15548687
ENSG00000123297 TSFM tumors 15849726
ENSG00000123297 TSFM tumour 16003559
ENSG00000123297 TSFM Ewing family of tumors 16006796
ENSG00000123297 TSFM tumors 16717057
ENSG00000123297 TSFM tumours 17557870
ENSG00000123297 TSFM tumors 17786311
ENSG00000123297 TSFM tumors 18838963
ENSG00000123297 TSFM Tumors 20153576
ENSG00000123297 TSFM Tumors 22266186
ENSG00000123297 TSFM tumors 22363342
ENSG00000123297 TSFM tumor 23552387
ENSG00000123297 TSFM tumors 26034869
ENSG00000123297 TSFM Cancer 29234655
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000123297 TSFM CHOL 0.026 high
ENSG00000123297 TSFM UCEC 0.0048 high
ENSG00000123297 TSFM ACC 0.013 low
ENSG00000123297 TSFM LGG 0.014 high
ENSG00000123297 TSFM LUSC 0.029 low
ENSG00000123297 TSFM HNSC 4e-04 high
ENSG00000123297 TSFM KICH 0.02 high
ENSG00000123297 TSFM LUAD 0.03 high
ENSG00000123297 TSFM PCPG 0.013 high
ENSG00000123297 TSFM THYM 0.03 low
ENSG00000123297 TSFM UCS 0.026 low
ENSG00000123297 TSFM ESCA 0.01 high
ENSG00000123297 TSFM KIRC 0.00046 high
ENSG00000123297 TSFM PRAD 0.0075 high
ENSG00000123297 TSFM SKCM 0.0018 high
ENSG00000123297 TSFM CESC 0.0047 low
ENSG00000123297 TSFM LIHC 0.031 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000123297 TSFM LUAD Amp 14.820003 0.337167 0.663913 0.327519
ENSG00000123297 TSFM LGG Amp 33.878055 0.348348 2.144374 0.068226
ENSG00000123297 TSFM ACC Amp 1.636341 0.393243 1.171077 0.777778
ENSG00000123297 TSFM SARC Amp 58.856737 1.661765 2.380582 0.303502
ENSG00000123297 TSFM GBM Amp 131.090477 1.119867 2.283863 0.218371
ENSG00000123297 TSFM SKCM Amp 7.870454 0.310289 1.025563 0.152589
ENSG00000123297 TSFM PCPG Amp 0.764816 0.071409 0.638335 0.098765
ENSG00000123297 TSFM STAD Amp 1.897103 0.167258 0.560342 0.219955