Ensembl ID ENSG00000123136 Gene ID 10212 Accession 17821
Gene Symbol DDX39A Alias BAT1;DDXL;BAT1L;DDX39;URH49 Full Name DExD-box helicase 39A
Position 19 : 14408798 - 14419383 Length 10586 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes a member of the DEAD box protein family. These proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene is thought to play a role in the prognosis of patients with gastrointestinal stromal tumors. A pseudogene of this gene is present on chromosome 13. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013]

ENSG00000123136 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000123136 DDX39A 1.01 7.25e-41 KIRC
ENSG00000123136 DDX39A 0.74 8.45e-15 HNSC
ENSG00000123136 DDX39A 1.05 3.03e-13 BLCA
ENSG00000123136 DDX39A 1.50 2.99e-83 BRCA
ENSG00000123136 DDX39A 1.11 3.92e-22 COAD
ENSG00000123136 DDX39A 1.60 6.86e-59 LUSC
ENSG00000123136 DDX39A 0.58 5.20e-13 PRAD
ENSG00000123136 DDX39A 1.72 1.54e-12 GBM
ENSG00000123136 DDX39A 0.88 7.10e-17 KIRP
ENSG00000123136 DDX39A 1.45 1.85e-35 LIHC
ENSG00000123136 DDX39A 1.75 5.42e-43 UCEC
ENSG00000123136 DDX39A 1.27 1.69e-13 ESCA
ENSG00000123136 DDX39A 1.40 9.61e-13 CHOL
ENSG00000123136 DDX39A 0.93 7.24e-24 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000123136 DDX39A cancer 17548965
ENSG00000123136 DDX39A cancer 21388492
ENSG00000123136 DDX39A gastrointestinal stromal tumor 22119546
ENSG00000123136 DDX39A bladder cancer 22494014
ENSG00000123136 DDX39A tumour 22723667
ENSG00000123136 DDX39A squamous cell cancer 23749908
ENSG00000123136 DDX39A pancreatic cancer 23898070
ENSG00000123136 DDX39A cancer 24679154
ENSG00000123136 DDX39A breast cancer 25918110
ENSG00000123136 DDX39A tumor 26469522
ENSG00000123136 DDX39A prostate cancer 28025139
ENSG00000123136 DDX39A colorectal cancer 29577224
ENSG00000123136 DDX39A tumor 29867138
ENSG00000123136 DDX39A tumor 31188873
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000123136 DDX39A MESO 0.00036 high
ENSG00000123136 DDX39A STAD 0.0023 low
ENSG00000123136 DDX39A CHOL 0.046 high
ENSG00000123136 DDX39A LGG 0.00026 high
ENSG00000123136 DDX39A KICH 0.032 high
ENSG00000123136 DDX39A THYM 0.00053 low
ENSG00000123136 DDX39A ESCA 0.0087 high
ENSG00000123136 DDX39A OV 0.012 low
ENSG00000123136 DDX39A DLBC 1e-04 low
ENSG00000123136 DDX39A BLCA 0.0011 low
ENSG00000123136 DDX39A LAML 0.021 high
ENSG00000123136 DDX39A SKCM 0.0053 high
ENSG00000123136 DDX39A CESC 0.00045 low
ENSG00000123136 DDX39A LIHC 0.0028 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000123136 DDX39A ACC Amp 0.822722 0.262001 1.064049 0.633333
ENSG00000123136 DDX39A UCEC Amp 7.575672 0.217286 0.775410 0.174397
ENSG00000123136 DDX39A OV Amp 34.021996 0.867877 1.030132 0.518135