Ensembl ID ENSG00000122566 Gene ID 3181 Accession 5033
Gene Symbol HNRNPA2B1 Alias OPMD2;RNPA2;HNRPA2;HNRPB1;SNRPB1;HNRNPA2;HNRNPB1;IBMPFD2;HNRPA2B1 Full Name heterogeneous nuclear ribonucleoprotein A2/B1
Position 7 : 26171151 - 26201481 Length 30331 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. [provided by RefSeq, Jul 2008]

ENSG00000122566 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000122566 HNRNPA2B1 0.58 4.55e-68 BRCA
ENSG00000122566 HNRNPA2B1 0.46 3.48e-15 COAD
ENSG00000122566 HNRNPA2B1 0.56 3.11e-23 LUSC
ENSG00000122566 HNRNPA2B1 0.34 1.63e-14 PRAD
ENSG00000122566 HNRNPA2B1 0.54 2.87e-13 STAD
ENSG00000122566 HNRNPA2B1 0.38 5.91e-14 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000122566 HNRNPA2B1 lung cancer 10197602
ENSG00000122566 HNRNPA2B1 cancers 10521432
ENSG00000122566 HNRNPA2B1 cancer 10632338
ENSG00000122566 HNRNPA2B1 cancer 10717246
ENSG00000122566 HNRNPA2B1 tumor 11062142
ENSG00000122566 HNRNPA2B1 tumour 11220665
ENSG00000122566 HNRNPA2B1 breast cancer 11510693
ENSG00000122566 HNRNPA2B1 breast cancer 11710964
ENSG00000122566 HNRNPA2B1 lung cancer 11714531
ENSG00000122566 HNRNPA2B1 lung cancer 11901918
ENSG00000122566 HNRNPA2B1 tumor 12495935
ENSG00000122566 HNRNPA2B1 lung cancer 12871781
ENSG00000122566 HNRNPA2B1 cancer 14692562
ENSG00000122566 HNRNPA2B1 lung cancers 15359725
ENSG00000122566 HNRNPA2B1 cancer 15375589
ENSG00000122566 HNRNPA2B1 lung cancer 15452456
ENSG00000122566 HNRNPA2B1 lung cancer 15583979
ENSG00000122566 HNRNPA2B1 gastric cancer 15759317
ENSG00000122566 HNRNPA2B1 AML 16732326
ENSG00000122566 HNRNPA2B1 non-small cell lung cancer 17067748
ENSG00000122566 HNRNPA2B1 lung tumors 17477362
ENSG00000122566 HNRNPA2B1 tumours 17671502
ENSG00000122566 HNRNPA2B1 cancer 18513434
ENSG00000122566 HNRNPA2B1 tumor 18519039
ENSG00000122566 HNRNPA2B1 cancer 18680105
ENSG00000122566 HNRNPA2B1 lung cancer 19414390
ENSG00000122566 HNRNPA2B1 lung cancer 19570713
ENSG00000122566 HNRNPA2B1 gastric cancer 20440860
ENSG00000122566 HNRNPA2B1 tumor 20604928
ENSG00000122566 HNRNPA2B1 lung cancer 20716340
ENSG00000122566 HNRNPA2B1 lung cancer 20807810
ENSG00000122566 HNRNPA2B1 cancer 20946641
ENSG00000122566 HNRNPA2B1 lung cancer 21108879
ENSG00000122566 HNRNPA2B1 cancer 21136816
ENSG00000122566 HNRNPA2B1 gastric cancer 21175803
ENSG00000122566 HNRNPA2B1 lung cancer 21215000
ENSG00000122566 HNRNPA2B1 lung cancer 21215005
ENSG00000122566 HNRNPA2B1 tumor 21321999
ENSG00000122566 HNRNPA2B1 tumor 21575478
ENSG00000122566 HNRNPA2B1 tumor 21586613
ENSG00000122566 HNRNPA2B1 lung cancer 22325225
ENSG00000122566 HNRNPA2B1 tumor 22372738
ENSG00000122566 HNRNPA2B1 prostate cancer 22438770
ENSG00000122566 HNRNPA2B1 pancreatic cancer 22622045
ENSG00000122566 HNRNPA2B1 pancreatic cancer 23525071
ENSG00000122566 HNRNPA2B1 cancer 23863836
ENSG00000122566 HNRNPA2B1 cervical cancer 24013563
ENSG00000122566 HNRNPA2B1 cancers 24428777
ENSG00000122566 HNRNPA2B1 cancers 24572810
ENSG00000122566 HNRNPA2B1 cancer 24823909
ENSG00000122566 HNRNPA2B1 tumors 24998203
ENSG00000122566 HNRNPA2B1 cancers 25586062
ENSG00000122566 HNRNPA2B1 gastric cancer 25818780
ENSG00000122566 HNRNPA2B1 tumor 26107993
ENSG00000122566 HNRNPA2B1 non-small cell lung cancer 26622731
ENSG00000122566 HNRNPA2B1 tumor 26774881
ENSG00000122566 HNRNPA2B1 cancer 27066085
ENSG00000122566 HNRNPA2B1 tumor 27215579
ENSG00000122566 HNRNPA2B1 pancreas cancer 27989750
ENSG00000122566 HNRNPA2B1 pancreatic cancer 28077929
ENSG00000122566 HNRNPA2B1 lung cancer 28638733
ENSG00000122566 HNRNPA2B1 lung cancer 28831131
ENSG00000122566 HNRNPA2B1 tumour 28850024
ENSG00000122566 HNRNPA2B1 cervical cancer 29328485
ENSG00000122566 HNRNPA2B1 non-small cell lung cancer 29509247
ENSG00000122566 HNRNPA2B1 tumors 29547514
ENSG00000122566 HNRNPA2B1 cancer 29720836
ENSG00000122566 HNRNPA2B1 tumor 29751524
ENSG00000122566 HNRNPA2B1 tumor 29774077
ENSG00000122566 HNRNPA2B1 tumor 29925861
ENSG00000122566 HNRNPA2B1 cancer 31193009
ENSG00000122566 HNRNPA2B1 tumor 31263129
ENSG00000122566 HNRNPA2B1 pancreatic cancer 31355266
ENSG00000122566 HNRNPA2B1 tumors 31551755
ENSG00000122566 HNRNPA2B1 breast cancer 31901866
ENSG00000122566 HNRNPA2B1 lung cancer 8631886
ENSG00000122566 HNRNPA2B1 lung cancer 9367062
ENSG00000122566 HNRNPA2B1 lung cancer 9676837
ENSG00000122566 HNRNPA2B1 lung cancer 9761751
ENSG00000122566 HNRNPA2B1 lung cancer 9815620
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
ENSG00000122566 HNRNPA2B1 prostate adenocarcinoma sequence_alteration 12.37% (234/1892) 2 entries
ENSG00000122566 HNRNPA2B1 prostate adenocarcinoma gene_fusion 12.37% (234/1892) 4 entries
ENSG00000122566 HNRNPA2B1 colorectal adenocarcinoma missense_variant 2.375% (27/1137) 2 entries
ENSG00000122566 HNRNPA2B1 esophageal adenocarcinoma sequence_alteration 1.598% (7/438) 1 entry
ENSG00000122566 HNRNPA2B1 colon adenocarcinoma missense_variant 2.384% (17/713) 3 entries
ENSG00000122566 HNRNPA2B1 nasopharyngeal squamous cell carcinoma sequence_alteration 1.198% (2/167) 1 entry
ENSG00000122566 HNRNPA2B1 squamous cell lung carcinoma sequence_alteration 0.7874% (6/762) 1 entry
ENSG00000122566 HNRNPA2B1 colorectal adenocarcinoma sequence_alteration 2.375% (27/1137) 1 entry
ENSG00000122566 HNRNPA2B1 esophageal squamous cell carcinoma missense_variant 0.7396% (5/676) 3 entries
ENSG00000122566 HNRNPA2B1 nasopharyngeal squamous cell carcinoma missense_variant 1.198% (2/167) 1 entry
ENSG00000122566 HNRNPA2B1 skin melanoma sequence_alteration 1.034% (10/967) 1 entry
ENSG00000122566 HNRNPA2B1 colon adenocarcinoma sequence_alteration 2.384% (17/713) 3 entries
ENSG00000122566 HNRNPA2B1 esophageal squamous cell carcinoma sequence_alteration 0.7396% (5/676) 1 entry
ENSG00000122566 HNRNPA2B1 pancreatic ductal adenocarcinoma sequence_alteration 0.3971% (5/1259) 1 entry
ENSG00000122566 HNRNPA2B1 basal cell carcinoma missense_variant 3.448% (2/58) 1 entry
ENSG00000122566 HNRNPA2B1 skin melanoma missense_variant 1.034% (10/967) 4 entries
ENSG00000122566 HNRNPA2B1 bladder carcinoma missense_variant 2.693% (15/557) 1 entry
ENSG00000122566 HNRNPA2B1 lung adenocarcinoma sequence_alteration 1.032% (12/1163) 2 entries
ENSG00000122566 HNRNPA2B1 hepatocellular carcinoma missense_variant 0.7778% (7/900) 1 entry
ENSG00000122566 HNRNPA2B1 hepatocellular carcinoma sequence_alteration 0.7778% (7/900) 1 entry
ENSG00000122566 HNRNPA2B1 cecum adenocarcinoma sequence_alteration 4.0% (5/125) 1 entry
ENSG00000122566 HNRNPA2B1 lung adenocarcinoma missense_variant 1.032% (12/1163) 4 entries
ENSG00000122566 HNRNPA2B1 extragonadal nonseminomatous germ cell tumor missense_variant 3.448% (1/29) 1 entry
ENSG00000122566 HNRNPA2B1 lung adenocarcinoma stop_gained 1.032% (12/1163) 1 entry
ENSG00000122566 HNRNPA2B1 brain glioblastoma sequence_alteration 0.108% (1/926) 1 entry
ENSG00000122566 HNRNPA2B1 oral squamous cell carcinoma sequence_alteration 0.4878% (1/205) 1 entry
ENSG00000122566 HNRNPA2B1 skin melanoma frameshift_variant 1.034% (10/967) 1 entry
ENSG00000122566 HNRNPA2B1 ovarian serous adenocarcinoma missense_variant 0.1486% (1/673) 1 entry
ENSG00000122566 HNRNPA2B1 small cell lung carcinoma sequence_alteration 0.3155% (1/317) 1 entry
ENSG00000122566 HNRNPA2B1 colorectal adenocarcinoma stop_gained 2.375% (27/1137) 1 entry
ENSG00000122566 HNRNPA2B1 colon adenocarcinoma conservative_inframe_deletion 2.384% (17/713) 1 entry
ENSG00000122566 HNRNPA2B1 cecum adenocarcinoma missense_variant 4.0% (5/125) 1 entry
ENSG00000122566 HNRNPA2B1 female breast carcinoma missense_variant 0.3745% (1/267) 1 entry
ENSG00000122566 HNRNPA2B1 pancreatic ductal adenocarcinoma missense_variant 0.3971% (5/1259) 1 entry
ENSG00000122566 HNRNPA2B1 colorectal adenocarcinoma frameshift_variant 2.375% (27/1137) 1 entry
ENSG00000122566 HNRNPA2B1 bladder transitional cell carcinoma missense_variant 0.7299% (1/137) 1 entry
ENSG00000122566 HNRNPA2B1 oral squamous cell carcinoma missense_variant 0.4878% (1/205) 1 entry
ENSG00000122566 HNRNPA2B1 hepatocellular carcinoma frameshift_variant 0.7778% (7/900) 1 entry
ENSG00000122566 HNRNPA2B1 prostate carcinoma sequence_alteration 0.2347% (1/426) 1 entry
ENSG00000122566 HNRNPA2B1 diffuse large B-cell lymphoma frameshift_variant 0.6579% (2/304) 1 entry
ENSG00000122566 HNRNPA2B1 Brain Stem Glioblastoma sequence_alteration 1.786% (1/56) 1 entry
ENSG00000122566 HNRNPA2B1 diffuse gastric adenocarcinoma missense_variant 1.266% (1/79) 1 entry
ENSG00000122566 HNRNPA2B1 basal cell carcinoma stop_gained 3.448% (2/58) 1 entry
ENSG00000122566 HNRNPA2B1 breast ductal carcinoma in situ sequence_alteration 50.0% (1/2) 1 entry
ENSG00000122566 HNRNPA2B1 mucosal melanoma sequence_alteration 7.143% (1/14) 1 entry
ENSG00000122566 HNRNPA2B1 basal cell carcinoma sequence_alteration 3.448% (2/58) 1 entry
ENSG00000122566 HNRNPA2B1 mucosal melanoma missense_variant 7.143% (1/14) 1 entry
ENSG00000122566 HNRNPA2B1 Ampulla of Vater Carcinoma frameshift_variant 1.176% (1/85) 1 entry
ENSG00000122566 HNRNPA2B1 colon carcinoma missense_variant 12.5% (1/8) 1 entry
ENSG00000122566 HNRNPA2B1 esophageal adenocarcinoma missense_variant 1.598% (7/438) 1 entry
ENSG00000122566 HNRNPA2B1 colon adenocarcinoma frameshift_variant 2.384% (17/713) 1 entry
ENSG00000122566 HNRNPA2B1 head and neck squamous cell carcinoma sequence_alteration 0.134% (1/746) 1 entry
ENSG00000122566 HNRNPA2B1 breast ductal carcinoma in situ missense_variant 50.0% (1/2) 1 entry
ENSG00000122566 HNRNPA2B1 adrenocortical adenoma stop_gained 2.5% (1/40) 1 entry
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000122566 HNRNPA2B1 MESO 0.018 high
ENSG00000122566 HNRNPA2B1 SARC 0.00023 high
ENSG00000122566 HNRNPA2B1 STAD 0.013 low
ENSG00000122566 HNRNPA2B1 UVM 0.00096 high
ENSG00000122566 HNRNPA2B1 LUSC 0.011 low
ENSG00000122566 HNRNPA2B1 HNSC 0.0063 high
ENSG00000122566 HNRNPA2B1 LUAD 0.00028 high
ENSG00000122566 HNRNPA2B1 THYM 0.0024 low
ENSG00000122566 HNRNPA2B1 ESCA 0.014 high
ENSG00000122566 HNRNPA2B1 OV 0.0066 low
ENSG00000122566 HNRNPA2B1 PRAD 0.0022 high
ENSG00000122566 HNRNPA2B1 TGCT 0.036 low
ENSG00000122566 HNRNPA2B1 BLCA 0.015 low
ENSG00000122566 HNRNPA2B1 LAML 0.00018 low
ENSG00000122566 HNRNPA2B1 GBM 0.05 low
ENSG00000122566 HNRNPA2B1 SKCM 0.026 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000122566 HNRNPA2B1 PRAD Amp 0.656974 0.044638 0.513481 0.211382
ENSG00000122566 HNRNPA2B1 OV Del 0.894754 0.179133 0.609449 0.276339