Ensembl ID
ENSG00000122257
Gene ID
5930
Accession
9889
Gene Symbol
RBBP6
Alias
PACT;MY038;P2P-R;RBQ-1;SNAMA
Full Name
RB binding protein 6, ubiquitin ligase
Position
16 : 24537693 - 24572863
Length
35171 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
ENSG00000122257 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000122257
RBBP6
esophageal cancer
15475430
ENSG00000122257
RBBP6
cancer
16396680
ENSG00000122257
RBBP6
lung tumor
21676486
ENSG00000122257
RBBP6
cancers
22139301
ENSG00000122257
RBBP6
tumour
23056957
ENSG00000122257
RBBP6
tumor
23799110
ENSG00000122257
RBBP6
breast cancer
24703106
ENSG00000122257
RBBP6
cancer
24993114
ENSG00000122257
RBBP6
breast cancer
25127414
ENSG00000122257
RBBP6
cancers
25319826
ENSG00000122257
RBBP6
gastric cancer
25379943
ENSG00000122257
RBBP6
cancers
25910411
ENSG00000122257
RBBP6
colon cancers
25955646
ENSG00000122257
RBBP6
colon cancers
26905308
ENSG00000122257
RBBP6
cancers
27536134
ENSG00000122257
RBBP6
cancer
28797070
ENSG00000122257
RBBP6
tumor
29369481
ENSG00000122257
RBBP6
cervical cancer
29501043
ENSG00000122257
RBBP6
Esophageal Cancer
30223275
ENSG00000122257
RBBP6
breast cancer
30237738
ENSG00000122257
RBBP6
cervical cancer
30886526
ENSG00000122257
RBBP6
cancer
31274515
ENSG00000122257
RBBP6
breast cancer
31534777
ENSG00000122257
RBBP6
colorectal cancer
31685801
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000122257
RBBP6
MESO
0.044
low
show
ENSG00000122257
RBBP6
PAAD
0.033
low
show
ENSG00000122257
RBBP6
UCEC
0.042
high
show
ENSG00000122257
RBBP6
ACC
0.02
high
show
ENSG00000122257
RBBP6
LGG
0.028
low
show
ENSG00000122257
RBBP6
LUSC
0.033
low
show
ENSG00000122257
RBBP6
HNSC
0.019
low
show
ENSG00000122257
RBBP6
READ
0.013
low
show
ENSG00000122257
RBBP6
KIRP
0.036
low
show
ENSG00000122257
RBBP6
OV
0.021
low
show
ENSG00000122257
RBBP6
PRAD
0.0097
high
show
ENSG00000122257
RBBP6
GBM
0.0092
low
show
ENSG00000122257
RBBP6
SKCM
0.00022
low
show
ENSG00000122257
RBBP6
LIHC
0.012
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000122257
RBBP6
GBM
Del
0.665510
0.051224
0.397206
0.155979
ENSG00000122257
RBBP6
BLCA
Amp
1.682818
0.199559
0.609403
0.218137
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