Ensembl ID
ENSG00000121060
Gene ID
7706
Accession
12932
Gene Symbol
TRIM25
Alias
EFP;Z147;RNF147;ZNF147
Full Name
tripartite motif containing 25
Position
17 : 56836387 - 56914080
Length
77694 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein is an RNA binding protein, functions as a ubiquitin E3 ligase and is involved in multiple cellular processes, including regulation of antiviral innate immunity. [provided by RefSeq, Sep 2021]
ENSG00000121060 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000121060
TRIM25
-0.5
6.67e-13
COAD
ENSG00000121060
TRIM25
0.81
2.73e-16
LIHC
ENSG00000121060
TRIM25
-0.5
1.59e-13
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000121060
TRIM25
breast cancer
11146438
ENSG00000121060
TRIM25
tumour
15743974
ENSG00000121060
TRIM25
breast cancer
15781984
ENSG00000121060
TRIM25
epithelial ovarian cancer
16140366
ENSG00000121060
TRIM25
breast cancer
16144914
ENSG00000121060
TRIM25
cancers
17202261
ENSG00000121060
TRIM25
breast cancer
17929166
ENSG00000121060
TRIM25
tumors
19290668
ENSG00000121060
TRIM25
tumor
21049605
ENSG00000121060
TRIM25
tumors
21204019
ENSG00000121060
TRIM25
breast cancer
21542805
ENSG00000121060
TRIM25
tumours
22452784
ENSG00000121060
TRIM25
Lung Cancer
26113559
ENSG00000121060
TRIM25
gastric cancer
26754079
ENSG00000121060
TRIM25
prostate cancer
27626314
ENSG00000121060
TRIM25
cancer
28620119
ENSG00000121060
TRIM25
Breast Cancer
28813674
ENSG00000121060
TRIM25
Cancer
28861931
ENSG00000121060
TRIM25
breast cancer
28958384
ENSG00000121060
TRIM25
prostate cancer
29379164
ENSG00000121060
TRIM25
breast cancer
30288100
ENSG00000121060
TRIM25
cancers
30323259
ENSG00000121060
TRIM25
breast cancer
30797711
ENSG00000121060
TRIM25
non-small-cell lung cancer
31099423
ENSG00000121060
TRIM25
prostate cancer
31137886
ENSG00000121060
TRIM25
tumor
31186535
ENSG00000121060
TRIM25
tumors
31326556
ENSG00000121060
TRIM25
tumor
31953436
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000121060
TRIM25
STAD
0.0012
low
show
ENSG00000121060
TRIM25
PAAD
0.00028
low
show
ENSG00000121060
TRIM25
ACC
0.026
high
show
ENSG00000121060
TRIM25
LGG
0.0012
high
show
ENSG00000121060
TRIM25
HNSC
0.037
low
show
ENSG00000121060
TRIM25
READ
0.0064
low
show
ENSG00000121060
TRIM25
KICH
0.0029
high
show
ENSG00000121060
TRIM25
LUAD
0.046
high
show
ENSG00000121060
TRIM25
PCPG
0.0034
low
show
ENSG00000121060
TRIM25
BRCA
0.01
high
show
ENSG00000121060
TRIM25
COAD
0.039
low
show
ENSG00000121060
TRIM25
ESCA
0.021
high
show
ENSG00000121060
TRIM25
DLBC
0.0058
high
show
ENSG00000121060
TRIM25
KIRC
0.023
low
show
ENSG00000121060
TRIM25
PRAD
0.017
low
show
ENSG00000121060
TRIM25
BLCA
0.0069
low
show
ENSG00000121060
TRIM25
LAML
0.027
high
show
ENSG00000121060
TRIM25
SKCM
0.02
high
show
ENSG00000121060
TRIM25
CESC
0.0086
high
show
ENSG00000121060
TRIM25
LIHC
9e-04
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000121060
TRIM25
LGG
Amp
1.530134
0.056360
0.576049
0.066277
ENSG00000121060
TRIM25
PAAD
Del
5.557737
0.122975
0.381178
0.250000
ENSG00000121060
TRIM25
SKCM
Amp
3.753360
0.210117
0.551103
0.313351
ENSG00000121060
TRIM25
LIHC
Amp
0.708920
0.111874
0.600166
0.324324
ENSG00000121060
TRIM25
BLCA
Amp
1.433932
0.191121
0.490666
0.433824
ENSG00000121060
TRIM25
BRCA
Amp
31.915058
0.434417
0.826845
0.344444
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.