Ensembl ID ENSG00000121058 Gene ID 8161 Accession 2184
Gene Symbol COIL Alias CLN80;p80-coilin Full Name coilin
Position 17 : 56938199 - 56961050 Length 22852 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq, Jul 2008]

ENSG00000121058 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000121058 COIL 0.46 1.00e-16 BRCA
ENSG00000121058 COIL 0.91 2.21e-38 LUSC
ENSG00000121058 COIL 0.53 2.15e-20 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000121058 COIL cancer 24659245
ENSG00000121058 COIL tumor 24859326
ENSG00000121058 COIL tumor 28337219
ENSG00000121058 COIL tumor 28536075
ENSG00000121058 COIL breast cancer 8207070
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000121058 COIL UVM 0.031 high
ENSG00000121058 COIL PAAD 0.022 low
ENSG00000121058 COIL UCEC 0.012 high
ENSG00000121058 COIL THCA 0.023 low
ENSG00000121058 COIL ACC 0.024 high
ENSG00000121058 COIL LGG 0.013 high
ENSG00000121058 COIL HNSC 0.0023 high
ENSG00000121058 COIL READ 0.021 low
ENSG00000121058 COIL KIRP 0.00026 high
ENSG00000121058 COIL KICH 0.00019 high
ENSG00000121058 COIL THYM 0.00074 low
ENSG00000121058 COIL BRCA 0.017 high
ENSG00000121058 COIL COAD 0.0033 low
ENSG00000121058 COIL OV 0.0032 low
ENSG00000121058 COIL KIRC 0.045 low
ENSG00000121058 COIL PRAD 0.012 high
ENSG00000121058 COIL SKCM 0.039 low
ENSG00000121058 COIL LIHC 0.00015 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000121058 COIL LGG Amp 1.530134 0.056360 0.576049 0.066277
ENSG00000121058 COIL PAAD Del 5.489132 0.122387 0.381178 0.250000
ENSG00000121058 COIL SKCM Amp 3.753360 0.210117 0.551103 0.313351
ENSG00000121058 COIL LIHC Amp 0.708920 0.111874 0.600166 0.324324
ENSG00000121058 COIL BLCA Amp 1.497537 0.193509 0.490086 0.436275
ENSG00000121058 COIL BRCA Amp 32.820359 0.440466 0.826060 0.348148