Ensembl ID ENSG00000121058 Gene ID 8161 Accession 2184
Gene Symbol COIL Alias CLN80;p80-coilin Full Name coilin
Position 17 : 56938199 - 56961050 Length 22852 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq, Jul 2008]

ENSG00000121058 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000121058 0.46 1.00e-16 BRCA
ENSG00000121058 0.91 2.21e-38 LUSC
ENSG00000121058 0.53 2.15e-20 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000121058 cancer 24659245
ENSG00000121058 tumor 24859326
ENSG00000121058 tumor 28337219
ENSG00000121058 tumor 28536075
ENSG00000121058 breast cancer 8207070
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000121058 UVM 0.031 high
ENSG00000121058 PAAD 0.022 low
ENSG00000121058 UCEC 0.012 high
ENSG00000121058 THCA 0.023 low
ENSG00000121058 ACC 0.024 high
ENSG00000121058 LGG 0.013 high
ENSG00000121058 HNSC 0.0023 high
ENSG00000121058 READ 0.021 low
ENSG00000121058 KIRP 0.00026 high
ENSG00000121058 KICH 0.00019 high
ENSG00000121058 THYM 0.00074 low
ENSG00000121058 BRCA 0.017 high
ENSG00000121058 COAD 0.0033 low
ENSG00000121058 OV 0.0032 low
ENSG00000121058 KIRC 0.045 low
ENSG00000121058 PRAD 0.012 high
ENSG00000121058 SKCM 0.039 low
ENSG00000121058 LIHC 0.00015 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000121058 LGG Amp 1.530134 0.056360 0.576049 0.066277
ENSG00000121058 PAAD Del 5.489132 0.122387 0.381178 0.250000
ENSG00000121058 SKCM Amp 3.753360 0.210117 0.551103 0.313351
ENSG00000121058 LIHC Amp 0.708920 0.111874 0.600166 0.324324
ENSG00000121058 BLCA Amp 1.497537 0.193509 0.490086 0.436275
ENSG00000121058 BRCA Amp 32.820359 0.440466 0.826060 0.348148