Ensembl ID ENSG00000121057 Gene ID 8165 Accession 367
Gene Symbol AKAP1 Alias AKAP;PRKA1;AKAP84;TDRD17;AKAP121;AKAP149;D-AKAP1;PPP1R43;SAKAP84 Full Name A-kinase anchoring protein 1
Position 17 : 57085092 - 57121346 Length 36255 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment. [provided by RefSeq, Jul 2008]

ENSG00000121057 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000121057 AKAP1 -0.5 5.15e-19 KIRC
ENSG00000121057 AKAP1 -0.7 1.79e-14 HNSC
ENSG00000121057 AKAP1 -0.4 2.99e-11 BRCA
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000121057 AKAP1 colon cancer 21559296
ENSG00000121057 AKAP1 breast cancer 23172368
ENSG00000121057 AKAP1 tumor 28569781
ENSG00000121057 AKAP1 tumors 29433456
ENSG00000121057 AKAP1 tumor 29928393
ENSG00000121057 AKAP1 tumor 30791886
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000121057 AKAP1 MESO 0.043 low
ENSG00000121057 AKAP1 SARC 0.016 low
ENSG00000121057 AKAP1 STAD 0.049 low
ENSG00000121057 AKAP1 UVM 0.01 high
ENSG00000121057 AKAP1 THCA 0.022 low
ENSG00000121057 AKAP1 ACC 0.033 low
ENSG00000121057 AKAP1 HNSC 0.018 high
ENSG00000121057 AKAP1 READ 0.0031 low
ENSG00000121057 AKAP1 PCPG 0.022 low
ENSG00000121057 AKAP1 BRCA 0.0094 high
ENSG00000121057 AKAP1 OV 0.02 low
ENSG00000121057 AKAP1 BLCA 0.036 low
ENSG00000121057 AKAP1 LAML 0.0067 high
ENSG00000121057 AKAP1 GBM 0.01 low
ENSG00000121057 AKAP1 SKCM 0.013 high
ENSG00000121057 AKAP1 LIHC 0.036 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000121057 AKAP1 LGG Amp 1.736394 0.059257 0.576481 0.068226
ENSG00000121057 AKAP1 PAAD Del 5.412070 0.121210 0.381178 0.250000
ENSG00000121057 AKAP1 SKCM Amp 3.753360 0.210117 0.551103 0.313351
ENSG00000121057 AKAP1 LIHC Amp 0.850168 0.116421 0.601019 0.327027
ENSG00000121057 AKAP1 BLCA Amp 0.801972 0.167822 0.471833 0.431373
ENSG00000121057 AKAP1 BRCA Amp 33.571658 0.445427 0.832453 0.349074