Ensembl ID ENSG00000120802 Gene ID 7112 Accession 11875
Gene Symbol TMPO Alias TP;LAP2;CMD1T;LEMD4;PRO0868 Full Name thymopoietin
Position 12 : 98515590 - 98550351 Length 34762 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary Through alternative splicing, this gene encodes several distinct LEM domain containing protein isoforms. LEM domain proteins include inner nuclear membrane and intranuclear proteins, and are involved in a variety of cellular functions including gene expression, chromatin organization, and replication and cell cycle control. The encoded alpha isoform is broadly diffuse in the nucleus and contains a lamin binding domain, while the beta and gamma isoforms are localized to the nuclear membrane and contain an HDAC3 interaction domain. The distinct isoforms may compete with each other when acting to chaperone other proteins and regulate transcription. [provided by RefSeq, Aug 2019]

ENSG00000120802 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000120802 TMPO 0.75 1.64e-29 BRCA
ENSG00000120802 TMPO 1.14 1.54e-36 LUSC
ENSG00000120802 TMPO 0.92 7.93e-17 STAD
ENSG00000120802 TMPO 0.77 1.71e-15 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000120802 TMPO MESO 0.0019 high
ENSG00000120802 TMPO SARC 0.0028 high
ENSG00000120802 TMPO STAD 0.0091 low
ENSG00000120802 TMPO UVM 0.038 high
ENSG00000120802 TMPO UCEC 0.023 low
ENSG00000120802 TMPO LUSC 0.00075 low
ENSG00000120802 TMPO HNSC 0.00061 low
ENSG00000120802 TMPO KICH 4e-04 high
ENSG00000120802 TMPO LUAD 0.0046 high
ENSG00000120802 TMPO THYM 0.0017 low
ENSG00000120802 TMPO UCS 0.024 low
ENSG00000120802 TMPO ESCA 0.025 high
ENSG00000120802 TMPO KIRC 0.0041 high
ENSG00000120802 TMPO PRAD 0.0053 low
ENSG00000120802 TMPO BLCA 0.025 low
ENSG00000120802 TMPO LAML 0.047 low
ENSG00000120802 TMPO SKCM 0.0037 low
ENSG00000120802 TMPO CESC 0.0079 low
ENSG00000120802 TMPO LIHC 0.012 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000120802 TMPO LUAD Del 0.625013 0.049936 0.283291 0.236434
ENSG00000120802 TMPO SARC Amp 0.829462 0.266840 0.813551 0.202335
ENSG00000120802 TMPO PAAD Del 1.597047 0.063547 0.356522 0.233696
ENSG00000120802 TMPO SKCM Del 1.407906 0.077880 0.425143 0.250681
ENSG00000120802 TMPO BRCA Del 1.517245 0.070773 0.387507 0.174074
ENSG00000120802 TMPO PRAD Amp 1.279500 0.054359 0.539573 0.071138
ENSG00000120802 TMPO OV Del 3.165164 0.221953 0.571717 0.333333