Ensembl ID ENSG00000120438 Gene ID 6950 Accession 11655
Gene Symbol TCP1 Alias CCT1;CCTa;D6S230E;CCT-alpha;TCP-1-alpha Full Name t-complex 1
Position 6 : 159778498 - 159789703 Length 11206 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found. [provided by RefSeq, Jun 2010]

ENSG00000120438 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000120438 TCP1 1.01 9.24e-38 LUSC
ENSG00000120438 TCP1 0.35 8.55e-11 PRAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000120438 TCP1 cancer 24714677
ENSG00000120438 TCP1 cancer 28455266
ENSG00000120438 TCP1 lung cancer 29294153
ENSG00000120438 TCP1 cancer 31101846
ENSG00000120438 TCP1 tumor 31158752
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000120438 TCP1 MESO 0.0013 high
ENSG00000120438 TCP1 SARC 0.0044 high
ENSG00000120438 TCP1 CHOL 0.029 high
ENSG00000120438 TCP1 UCEC 0.022 high
ENSG00000120438 TCP1 ACC 0.0018 high
ENSG00000120438 TCP1 LUSC 0.015 low
ENSG00000120438 TCP1 HNSC 0.002 high
ENSG00000120438 TCP1 READ 0.001 low
ENSG00000120438 TCP1 KICH 0.038 high
ENSG00000120438 TCP1 LUAD 0.00077 high
ENSG00000120438 TCP1 PCPG 0.019 high
ENSG00000120438 TCP1 THYM 0.00045 low
ENSG00000120438 TCP1 BRCA 0.00029 high
ENSG00000120438 TCP1 UCS 0.027 high
ENSG00000120438 TCP1 ESCA 0.00041 high
ENSG00000120438 TCP1 OV 0.011 high
ENSG00000120438 TCP1 KIRC 0.00032 low
ENSG00000120438 TCP1 SKCM 0.032 low
ENSG00000120438 TCP1 CESC 0.0081 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000120438 TCP1 LUAD Del 1.506608 0.061896 0.376420 0.501938
ENSG00000120438 TCP1 LGG Del 1.321861 0.045796 0.575039 0.155945
ENSG00000120438 TCP1 CESC Del 2.333196 0.096154 0.481332 0.328814
ENSG00000120438 TCP1 GBM Del 4.638210 0.089689 0.552181 0.273830
ENSG00000120438 TCP1 SKCM Del 5.894105 0.131570 0.558546 0.596730
ENSG00000120438 TCP1 LIHC Del 5.455484 0.126114 0.612929 0.378378
ENSG00000120438 TCP1 BLCA Del 0.721973 0.076953 0.373661 0.460784
ENSG00000120438 TCP1 BRCA Del 12.306208 0.123402 0.483997 0.337963
ENSG00000120438 TCP1 STAD Del 1.005791 0.065057 0.352044 0.206349
ENSG00000120438 TCP1 UCEC Del 0.812437 0.049211 0.464330 0.085343
ENSG00000120438 TCP1 MESO Del 1.706405 0.165509 0.535534 0.413793
ENSG00000120438 TCP1 KIRC Del 9.030080 0.063155 0.462135 0.285985
ENSG00000120438 TCP1 UVM Del 0.698242 0.056839 0.814785 0.287500
ENSG00000120438 TCP1 OV Del 30.971670 0.456433 0.661081 0.644214