Ensembl ID ENSG00000119953 Gene ID 10285 Accession 16900
Gene Symbol SMNDC1 Alias SMNR;SPF30;TDRD16C Full Name survival motor neuron domain containing 1
Position 10 : 110290730 - 110304938 Length 14209 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. [provided by RefSeq, Jul 2008]

ENSG00000119953 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000119953 SMNDC1 0.46 2.23e-13 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000119953 SMNDC1 skin cancer 23651270
ENSG00000119953 SMNDC1 ovarian cancer 24831101
ENSG00000119953 SMNDC1 skin tumor 27003466
ENSG00000119953 SMNDC1 cancer 31911676
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000119953 SMNDC1 MESO 0.039 high
ENSG00000119953 SMNDC1 PAAD 0.00054 high
ENSG00000119953 SMNDC1 UCEC 0.041 high
ENSG00000119953 SMNDC1 LGG 0.00064 low
ENSG00000119953 SMNDC1 LUSC 0.048 low
ENSG00000119953 SMNDC1 HNSC 0.0017 high
ENSG00000119953 SMNDC1 READ 0.028 high
ENSG00000119953 SMNDC1 LUAD 0.0028 high
ENSG00000119953 SMNDC1 PCPG 0.042 high
ENSG00000119953 SMNDC1 THYM 0.03 low
ENSG00000119953 SMNDC1 UCS 0.031 low
ENSG00000119953 SMNDC1 ESCA 0.0081 high
ENSG00000119953 SMNDC1 OV 0.026 low
ENSG00000119953 SMNDC1 GBM 0.01 low
ENSG00000119953 SMNDC1 SKCM 0.036 low
ENSG00000119953 SMNDC1 CESC 0.02 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000119953 SMNDC1 CHOL Del 0.773813 0.210515 0.458947 0.250000
ENSG00000119953 SMNDC1 LUSC Del 0.859635 0.068071 0.354575 0.514970
ENSG00000119953 SMNDC1 LGG Del 7.224798 0.088849 0.581380 0.247563
ENSG00000119953 SMNDC1 CESC Del 0.831825 0.069730 0.443921 0.301695
ENSG00000119953 SMNDC1 READ Del 0.781899 0.074801 0.404948 0.296970
ENSG00000119953 SMNDC1 COAD Del 3.749419 0.071296 0.359309 0.232816
ENSG00000119953 SMNDC1 GBM Del 0.888717 0.054414 0.697832 0.883882
ENSG00000119953 SMNDC1 LIHC Del 2.260263 0.089245 0.482454 0.267568
ENSG00000119953 SMNDC1 BLCA Del 2.577334 0.106408 0.395802 0.416667
ENSG00000119953 SMNDC1 BRCA Del 7.368039 0.103954 0.389287 0.302778
ENSG00000119953 SMNDC1 STAD Del 1.584475 0.073159 0.357935 0.210884
ENSG00000119953 SMNDC1 UCEC Del 2.812143 0.070905 0.539450 0.120594
ENSG00000119953 SMNDC1 MESO Del 2.667247 0.200352 0.485373 0.356322
ENSG00000119953 SMNDC1 OV Del 6.434930 0.263464 0.526097 0.367876