Ensembl ID ENSG00000117592 Gene ID 9588 Accession 16753
Gene Symbol PRDX6 Alias PRX;p29;AOP2;1-Cys;NSGPx;aiPLA2;LPCAT-5;HEL-S-128m Full Name peroxiredoxin 6
Position 1 : 173477335 - 173488815 Length 11481 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008]

ENSG00000117592 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000117592 PRDX6 -0.5 4.94e-16 BRCA
ENSG00000117592 PRDX6 -1.4 6.30e-83 COAD
ENSG00000117592 PRDX6 -1.4 1.42e-16 READ
ENSG00000117592 PRDX6 -1.7 3.50e-20 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000117592 PRDX6 prostate cancer 15342369
ENSG00000117592 PRDX6 cancer 16251605
ENSG00000117592 PRDX6 breast cancer 1720785
ENSG00000117592 PRDX6 breast cancer 17980029
ENSG00000117592 PRDX6 colon cancer 19257893
ENSG00000117592 PRDX6 lung cancer 19937138
ENSG00000117592 PRDX6 lung cancer 20354123
ENSG00000117592 PRDX6 tumor 20844677
ENSG00000117592 PRDX6 ovarian cancer 21166495
ENSG00000117592 PRDX6 tumor 2159436
ENSG00000117592 PRDX6 pancreatic cancer 21691750
ENSG00000117592 PRDX6 breast cancer 22200848
ENSG00000117592 PRDX6 tumor 22279397
ENSG00000117592 PRDX6 cancer 22366088
ENSG00000117592 PRDX6 cancer 22539432
ENSG00000117592 PRDX6 tumour 22869254
ENSG00000117592 PRDX6 prostate cancer 23077524
ENSG00000117592 PRDX6 cancer 23113308
ENSG00000117592 PRDX6 gastric cancer 23158669
ENSG00000117592 PRDX6 tumor 23217164
ENSG00000117592 PRDX6 breast cancer 23489758
ENSG00000117592 PRDX6 tumor 23576553
ENSG00000117592 PRDX6 Lung tumor 23643677
ENSG00000117592 PRDX6 lung cancer 23692979
ENSG00000117592 PRDX6 cancers 23868380
ENSG00000117592 PRDX6 cancer 23890079
ENSG00000117592 PRDX6 tumor 24512906
ENSG00000117592 PRDX6 tumor 24618722
ENSG00000117592 PRDX6 tumor 24858037
ENSG00000117592 PRDX6 breast cancer 24932247
ENSG00000117592 PRDX6 tumour 25208999
ENSG00000117592 PRDX6 tumor 25582888
ENSG00000117592 PRDX6 skin tumors 25594034
ENSG00000117592 PRDX6 Tumour 25686213
ENSG00000117592 PRDX6 tumors 25724726
ENSG00000117592 PRDX6 lung tumor 26061816
ENSG00000117592 PRDX6 cancer 26293541
ENSG00000117592 PRDX6 Prostate Cancer 26637857
ENSG00000117592 PRDX6 prostate cancer 27197287
ENSG00000117592 PRDX6 cancer 27288264
ENSG00000117592 PRDX6 cancer 27484502
ENSG00000117592 PRDX6 cancer 28357082
ENSG00000117592 PRDX6 tumor 28513872
ENSG00000117592 PRDX6 lung cancer 29109765
ENSG00000117592 PRDX6 tumor 29689709
ENSG00000117592 PRDX6 breast cancer 29966525
ENSG00000117592 PRDX6 ovarian cancer 30104402
ENSG00000117592 PRDX6 tumors 30410598
ENSG00000117592 PRDX6 tumor 30426295
ENSG00000117592 PRDX6 tumor 30480549
ENSG00000117592 PRDX6 Colorectal Cancer 30562740
ENSG00000117592 PRDX6 lung cancer 30568461
ENSG00000117592 PRDX6 tumor 30639960
ENSG00000117592 PRDX6 cancer 30763573
ENSG00000117592 PRDX6 cancers 31402980
ENSG00000117592 PRDX6 cancers 31489244
ENSG00000117592 PRDX6 tumor 31640461
ENSG00000117592 PRDX6 breast cancer 31814764
ENSG00000117592 PRDX6 Non-Small Cell Lung Cancer 31819528
ENSG00000117592 PRDX6 breast tumors 31839604
ENSG00000117592 PRDX6 tumour 8063016
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000117592 PRDX6 MESO 0.009 low
ENSG00000117592 PRDX6 UVM 0.012 low
ENSG00000117592 PRDX6 PAAD 0.0023 high
ENSG00000117592 PRDX6 UCEC 0.0011 high
ENSG00000117592 PRDX6 ACC 0.0035 high
ENSG00000117592 PRDX6 KIRP 0.00012 high
ENSG00000117592 PRDX6 KICH 0.0028 high
ENSG00000117592 PRDX6 LUAD 0.0051 high
ENSG00000117592 PRDX6 PCPG 0.0035 high
ENSG00000117592 PRDX6 THYM 0.00087 high
ENSG00000117592 PRDX6 OV 0.00085 low
ENSG00000117592 PRDX6 KIRC 0.0018 high
ENSG00000117592 PRDX6 BLCA 0.0064 high
ENSG00000117592 PRDX6 SKCM 0.015 low
ENSG00000117592 PRDX6 LIHC 0.004 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000117592 PRDX6 LUSC Amp 1.581617 0.223280 0.528030 0.514970
ENSG00000117592 PRDX6 LUAD Amp 1.860872 0.146395 0.505990 0.711240
ENSG00000117592 PRDX6 CESC Amp 0.827922 0.133049 0.611826 0.532203
ENSG00000117592 PRDX6 SARC Amp 5.153415 0.459907 0.822623 0.342412
ENSG00000117592 PRDX6 SKCM Amp 1.855013 0.157304 0.689177 0.539510
ENSG00000117592 PRDX6 LIHC Amp 7.293605 0.246806 0.870890 0.735135
ENSG00000117592 PRDX6 DLBC Amp 2.314444 0.347570 0.632214 0.312500
ENSG00000117592 PRDX6 BLCA Amp 7.125906 0.334597 0.589020 0.446078
ENSG00000117592 PRDX6 BRCA Amp 4.467477 0.205048 0.760087 0.735185
ENSG00000117592 PRDX6 UCEC Amp 1.846267 0.129812 0.822267 0.437848
ENSG00000117592 PRDX6 OV Amp 1.649376 0.362969 0.667234 0.550950