Ensembl ID ENSG00000117450 Gene ID 5052 Accession 9352
Gene Symbol PRDX1 Alias PAG;PAGA;PAGB;PRX1;PRXI;MSP23;NKEFA;TDPX2;NKEF-A Full Name peroxiredoxin 1
Position 1 : 45510914 - 45542732 Length 31819 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Non-canonical_RBPs
Summary This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jan 2011]

ENSG00000117450 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000117450 PRDX1 -0.5 1.52e-18 KIRC
ENSG00000117450 PRDX1 0.98 5.54e-49 BRCA
ENSG00000117450 PRDX1 -1.1 5.55e-39 KICH
ENSG00000117450 PRDX1 1.20 1.43e-18 LUSC
ENSG00000117450 PRDX1 0.96 3.32e-18 UCEC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000117450 PRDX1 tumor 12140735
ENSG00000117450 PRDX1 cancer 12861054
ENSG00000117450 PRDX1 prostate cancer 15117422
ENSG00000117450 PRDX1 cancer 15986332
ENSG00000117450 PRDX1 cancers 17234762
ENSG00000117450 PRDX1 non-small cell lung cancer 17606720
ENSG00000117450 PRDX1 breast cancer 17980029
ENSG00000117450 PRDX1 tumor 17988525
ENSG00000117450 PRDX1 breast tumors 17996735
ENSG00000117450 PRDX1 lung cancer 18413821
ENSG00000117450 PRDX1 cancer 18549262
ENSG00000117450 PRDX1 thyroid tumors 18665625
ENSG00000117450 PRDX1 cancer 19369943
ENSG00000117450 PRDX1 tumor 20018613
ENSG00000117450 PRDX1 thyroid cancer 20410161
ENSG00000117450 PRDX1 Breast Cancer 20631257
ENSG00000117450 PRDX1 tumor 21031435
ENSG00000117450 PRDX1 prostate cancer 21343392
ENSG00000117450 PRDX1 cancer 21458040
ENSG00000117450 PRDX1 esophageal cancer 21468086
ENSG00000117450 PRDX1 tumor 21589862
ENSG00000117450 PRDX1 tumor 21753893
ENSG00000117450 PRDX1 Ovarian Cancer 21980378
ENSG00000117450 PRDX1 tumours 22158042
ENSG00000117450 PRDX1 malignant brain tumor 22192797
ENSG00000117450 PRDX1 cancer 22446018
ENSG00000117450 PRDX1 cancer 22448089
ENSG00000117450 PRDX1 tumor 22475482
ENSG00000117450 PRDX1 lung cancer 22537621
ENSG00000117450 PRDX1 tumor 22947094
ENSG00000117450 PRDX1 lung cancer 23042266
ENSG00000117450 PRDX1 gallbladder cancer 23065574
ENSG00000117450 PRDX1 cancer 23113308
ENSG00000117450 PRDX1 cancers 23277276
ENSG00000117450 PRDX1 tumor 23386615
ENSG00000117450 PRDX1 Tumor 23762225
ENSG00000117450 PRDX1 tumor 23914992
ENSG00000117450 PRDX1 breast cancer 23971998
ENSG00000117450 PRDX1 tumor 24009050
ENSG00000117450 PRDX1 tumors 24023558
ENSG00000117450 PRDX1 prostate cancer 24281119
ENSG00000117450 PRDX1 cancer 24309932
ENSG00000117450 PRDX1 pancreatic cancer 24685079
ENSG00000117450 PRDX1 GBM 24728830
ENSG00000117450 PRDX1 GBM 24838487
ENSG00000117450 PRDX1 cancer 24872842
ENSG00000117450 PRDX1 breast cancer 24932247
ENSG00000117450 PRDX1 breast cancer 25011585
ENSG00000117450 PRDX1 oral cancer 25162226
ENSG00000117450 PRDX1 pituitary tumor 25188299
ENSG00000117450 PRDX1 lung cancer 25232487
ENSG00000117450 PRDX1 pancreatic cancer 25426613
ENSG00000117450 PRDX1 pancreatic cancer 25434328
ENSG00000117450 PRDX1 breast cancer 25454514
ENSG00000117450 PRDX1 oligodendroglial tumors 25484280
ENSG00000117450 PRDX1 cancer 25579166
ENSG00000117450 PRDX1 cancer 25607351
ENSG00000117450 PRDX1 cancers 25632391
ENSG00000117450 PRDX1 cancer 26461286
ENSG00000117450 PRDX1 liver cancer 26478675
ENSG00000117450 PRDX1 liver tumor 26569310
ENSG00000117450 PRDX1 tumor 26622762
ENSG00000117450 PRDX1 DLBCL 26636537
ENSG00000117450 PRDX1 anaplastic thyroid cancer 26664298
ENSG00000117450 PRDX1 Cancer 26689287
ENSG00000117450 PRDX1 tumors 26707944
ENSG00000117450 PRDX1 oral cancer 26722300
ENSG00000117450 PRDX1 tumor 26722370
ENSG00000117450 PRDX1 DLBCL 26752561
ENSG00000117450 PRDX1 colorectal cancer 27158373
ENSG00000117450 PRDX1 cancer 27306414
ENSG00000117450 PRDX1 cancer 27388124
ENSG00000117450 PRDX1 cancer 27418953
ENSG00000117450 PRDX1 Breast Cancer 27503926
ENSG00000117450 PRDX1 cervical cancer 27601940
ENSG00000117450 PRDX1 cancer 27653015
ENSG00000117450 PRDX1 tumor 28357082
ENSG00000117450 PRDX1 tumor 28398822
ENSG00000117450 PRDX1 cancer 28453520
ENSG00000117450 PRDX1 pancreatic cancer 29190947
ENSG00000117450 PRDX1 Oral Cancer 29218012
ENSG00000117450 PRDX1 colon cancer 29434945
ENSG00000117450 PRDX1 tumor 29477046
ENSG00000117450 PRDX1 tumor 29492195
ENSG00000117450 PRDX1 cancer 29512938
ENSG00000117450 PRDX1 cancer 29541251
ENSG00000117450 PRDX1 oligodendroglial tumors 29582423
ENSG00000117450 PRDX1 Gastric Cancer 29656298
ENSG00000117450 PRDX1 colorectal cancer 29673884
ENSG00000117450 PRDX1 colorectal cancer 29687844
ENSG00000117450 PRDX1 cancer 29773556
ENSG00000117450 PRDX1 colon cancer 29802121
ENSG00000117450 PRDX1 tumors 29908016
ENSG00000117450 PRDX1 cancer 29929436
ENSG00000117450 PRDX1 ovarian cancer 30104402
ENSG00000117450 PRDX1 cancer 30177848
ENSG00000117450 PRDX1 breast cancer 30287919
ENSG00000117450 PRDX1 cancer 30356039
ENSG00000117450 PRDX1 cancer 30420615
ENSG00000117450 PRDX1 ovarian cancer 30464523
ENSG00000117450 PRDX1 pancreatic cancer 30464602
ENSG00000117450 PRDX1 lung cancer 30568461
ENSG00000117450 PRDX1 tumor 30661989
ENSG00000117450 PRDX1 tumor 30711520
ENSG00000117450 PRDX1 gastric cancer 30886505
ENSG00000117450 PRDX1 prostate cancer 30981892
ENSG00000117450 PRDX1 tumor 30987822
ENSG00000117450 PRDX1 oral cancer 31118684
ENSG00000117450 PRDX1 tumor 31298537
ENSG00000117450 PRDX1 breast cancer 31370904
ENSG00000117450 PRDX1 tumor 31402980
ENSG00000117450 PRDX1 breast cancer 31412312
ENSG00000117450 PRDX1 breast cancer 31419957
ENSG00000117450 PRDX1 tumor 31429766
ENSG00000117450 PRDX1 cancer 31470801
ENSG00000117450 PRDX1 tumor 31477836
ENSG00000117450 PRDX1 breast cancer 31485630
ENSG00000117450 PRDX1 tumor 31533285
ENSG00000117450 PRDX1 ovarian cancer 31559796
ENSG00000117450 PRDX1 tumor 31583069
ENSG00000117450 PRDX1 breast cancer 31686989
ENSG00000117450 PRDX1 breast cancer 31814764
ENSG00000117450 PRDX1 Esophageal Cancer 31920397
ENSG00000117450 PRDX1 cervical cancer 31956363
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000117450 PRDX1 MESO 0.0035 high
ENSG00000117450 PRDX1 PAAD 0.0016 high
ENSG00000117450 PRDX1 HNSC 0.013 high
ENSG00000117450 PRDX1 READ 0.012 low
ENSG00000117450 PRDX1 KIRP 0.00011 high
ENSG00000117450 PRDX1 LUAD 0.034 high
ENSG00000117450 PRDX1 BRCA 0.009 high
ENSG00000117450 PRDX1 OV 0.046 low
ENSG00000117450 PRDX1 DLBC 0.024 low
ENSG00000117450 PRDX1 KIRC 0.0086 high
ENSG00000117450 PRDX1 BLCA 0.00043 high
ENSG00000117450 PRDX1 LAML 0.044 high
ENSG00000117450 PRDX1 SKCM 0.033 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000117450 PRDX1 CHOL Del 1.033657 0.234574 0.607663 0.277778
ENSG00000117450 PRDX1 KIRP Del 0.670901 0.026314 0.602146 0.135417
ENSG00000117450 PRDX1 LIHC Del 1.633310 0.080760 0.497441 0.275676
ENSG00000117450 PRDX1 PCPG Del 3.227544 0.105592 0.676443 0.660494
ENSG00000117450 PRDX1 UVM Del 1.063142 0.074432 0.773478 0.287500
ENSG00000117450 PRDX1 OV Amp 3.387118 0.413199 0.604906 0.443869