Ensembl ID
ENSG00000116830
Gene ID
8458
Accession
12398
Gene Symbol
TTF2
Alias
F2;HuF2;ZGRF6
Full Name
transcription termination factor 2
Position
1 : 117060326 - 117107453
Length
47128 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
This gene encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing. [provided by RefSeq, Jul 2008]
ENSG00000116830 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000116830
TTF2
0.80
6.27e-25
COAD
ENSG00000116830
TTF2
1.45
9.46e-52
LUSC
ENSG00000116830
TTF2
0.98
2.65e-16
LIHC
ENSG00000116830
TTF2
0.91
5.63e-17
STAD
ENSG00000116830
TTF2
1.14
2.32e-23
UCEC
ENSG00000116830
TTF2
1.79
6.74e-16
CHOL
ENSG00000116830
TTF2
0.88
3.32e-30
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000116830
TTF2
MESO
0.0034
high
show
ENSG00000116830
TTF2
SARC
0.0016
high
show
ENSG00000116830
TTF2
STAD
0.00095
low
show
ENSG00000116830
TTF2
CHOL
0.017
low
show
ENSG00000116830
TTF2
PAAD
0.0082
high
show
ENSG00000116830
TTF2
UCEC
0.0019
low
show
ENSG00000116830
TTF2
ACC
0.019
high
show
ENSG00000116830
TTF2
LUSC
0.0036
low
show
ENSG00000116830
TTF2
HNSC
0.001
low
show
ENSG00000116830
TTF2
KIRP
0.03
high
show
ENSG00000116830
TTF2
LUAD
0.037
high
show
ENSG00000116830
TTF2
COAD
0.019
low
show
ENSG00000116830
TTF2
UCS
0.003
high
show
ENSG00000116830
TTF2
PRAD
0.001
low
show
ENSG00000116830
TTF2
BLCA
0.017
high
show
ENSG00000116830
TTF2
LAML
0.017
high
show
ENSG00000116830
TTF2
SKCM
0.044
high
show
ENSG00000116830
TTF2
LIHC
0.00017
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000116830
TTF2
LUSC
Del
16.540499
0.190598
0.414669
0.439122
ENSG00000116830
TTF2
LUAD
Del
11.679656
0.137639
0.357139
0.292636
ENSG00000116830
TTF2
CESC
Del
1.311496
0.079272
0.436669
0.105085
ENSG00000116830
TTF2
READ
Del
0.882647
0.077426
0.392449
0.321212
ENSG00000116830
TTF2
COAD
Del
1.912161
0.055213
0.420073
0.246120
ENSG00000116830
TTF2
PAAD
Amp
1.677439
0.114240
0.677254
0.086957
ENSG00000116830
TTF2
ESCA
Del
2.469896
0.144746
0.405461
0.315217
ENSG00000116830
TTF2
SKCM
Amp
0.728284
0.120509
0.585227
0.256131
ENSG00000116830
TTF2
SKCM
Del
2.854492
0.097940
0.431374
0.198910
ENSG00000116830
TTF2
HNSC
Del
17.198052
0.158457
0.411813
0.245211
ENSG00000116830
TTF2
PCPG
Del
17.707156
0.272667
0.700795
0.697531
ENSG00000116830
TTF2
DLBC
Del
1.214698
0.153375
0.462490
0.208333
ENSG00000116830
TTF2
BRCA
Del
2.118905
0.075485
0.385167
0.245370
ENSG00000116830
TTF2
STAD
Del
2.450097
0.083961
0.380399
0.204082
ENSG00000116830
TTF2
MESO
Del
4.566606
0.256352
0.566809
0.310345
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