Ensembl ID ENSG00000116791 Gene ID 1429 Accession 2419
Gene Symbol CRYZ Alias NA Full Name crystallin zeta
Position 1 : 74705482 - 74733408 Length 27927 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Non-canonical_RBPs
Summary Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist. [provided by RefSeq, Sep 2008]

ENSG00000116791 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000116791 CRYZ -1.0 4.78e-32 PRAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000116791 CRYZ cancer 10077223
ENSG00000116791 CRYZ colon cancer 10391098
ENSG00000116791 CRYZ lung cancer 10397241
ENSG00000116791 CRYZ lung cancer 10591487
ENSG00000116791 CRYZ colorectal cancer 10663383
ENSG00000116791 CRYZ tumour 10718341
ENSG00000116791 CRYZ colorectal cancer 11023538
ENSG00000116791 CRYZ tumors 11035253
ENSG00000116791 CRYZ tumors 11040064
ENSG00000116791 CRYZ acute myeloid leukemia (AML) 11051261
ENSG00000116791 CRYZ cancer 11122850
ENSG00000116791 CRYZ cancer 11156173
ENSG00000116791 CRYZ tumor 11171586
ENSG00000116791 CRYZ tumor 11248489
ENSG00000116791 CRYZ lung cancer 11319169
ENSG00000116791 CRYZ tumor 11351248
ENSG00000116791 CRYZ prostate cancer 11412042
ENSG00000116791 CRYZ lung cancer 11551408
ENSG00000116791 CRYZ tumors 11600935
ENSG00000116791 CRYZ small cell lung cancer 11679176
ENSG00000116791 CRYZ cancer 11693537
ENSG00000116791 CRYZ tumor 11709197
ENSG00000116791 CRYZ bladder cancer 11710826
ENSG00000116791 CRYZ peritoneal cancer 11773862
ENSG00000116791 CRYZ acute myeloid leukemia (AML) 11840286
ENSG00000116791 CRYZ cancer 11916749
ENSG00000116791 CRYZ cancer 11956078
ENSG00000116791 CRYZ cancers 12018106
ENSG00000116791 CRYZ colorectal cancer 12419832
ENSG00000116791 CRYZ AML 12468438
ENSG00000116791 CRYZ colorectal cancer 12529991
ENSG00000116791 CRYZ lung cancer 12711112
ENSG00000116791 CRYZ tumor 12775025
ENSG00000116791 CRYZ tumor 1340765
ENSG00000116791 CRYZ tumor 1445367
ENSG00000116791 CRYZ pancreatic cancer 14500388
ENSG00000116791 CRYZ colon-cancer 1458556
ENSG00000116791 CRYZ esophageal cancer 14669229
ENSG00000116791 CRYZ tumour 14999778
ENSG00000116791 CRYZ tumour 15010841
ENSG00000116791 CRYZ tumor 1507207
ENSG00000116791 CRYZ AML 15198733
ENSG00000116791 CRYZ bladder cancer 15219943
ENSG00000116791 CRYZ susceptibility to breast cancer 15280903
ENSG00000116791 CRYZ tumour 1530580
ENSG00000116791 CRYZ prostate cancer 15315711
ENSG00000116791 CRYZ bladder cancers 15365958
ENSG00000116791 CRYZ bladder cancers 15375541
ENSG00000116791 CRYZ cervical cancer 15661231
ENSG00000116791 CRYZ pancreatic cancers 15662131
ENSG00000116791 CRYZ lung cancer 15808404
ENSG00000116791 CRYZ pancreatic cancer 16003741
ENSG00000116791 CRYZ colorectal cancer 16039674
ENSG00000116791 CRYZ cancer 16097803
ENSG00000116791 CRYZ lung cancer 16172245
ENSG00000116791 CRYZ cancer 16314070
ENSG00000116791 CRYZ cancer 16361576
ENSG00000116791 CRYZ cancer 16494910
ENSG00000116791 CRYZ tumor 1651729
ENSG00000116791 CRYZ tumors 16883563
ENSG00000116791 CRYZ ovarian cancer 17332305
ENSG00000116791 CRYZ lung cancer 17337085
ENSG00000116791 CRYZ small cell lung cancer 17410034
ENSG00000116791 CRYZ lung cancer 17428572
ENSG00000116791 CRYZ tumour 17571194
ENSG00000116791 CRYZ tumors 17574288
ENSG00000116791 CRYZ cancer 17603928
ENSG00000116791 CRYZ cancer 17786182
ENSG00000116791 CRYZ tumour 17878521
ENSG00000116791 CRYZ tumour 17971996
ENSG00000116791 CRYZ tumor 17999461
ENSG00000116791 CRYZ cancers 18062662
ENSG00000116791 CRYZ tumors 18091324
ENSG00000116791 CRYZ cancer 18283592
ENSG00000116791 CRYZ Cancer 18361512
ENSG00000116791 CRYZ tumour 18388957
ENSG00000116791 CRYZ colorectal cancer 18444152
ENSG00000116791 CRYZ cancer 18474416
ENSG00000116791 CRYZ tumor 18794327
ENSG00000116791 CRYZ cancer 18820947
ENSG00000116791 CRYZ cancer 1899380
ENSG00000116791 CRYZ colon cancer 19256554
ENSG00000116791 CRYZ colon cancer 19424637
ENSG00000116791 CRYZ cancer 19657853
ENSG00000116791 CRYZ tumor 19755658
ENSG00000116791 CRYZ tumor 19877692
ENSG00000116791 CRYZ skin tumors 20103645
ENSG00000116791 CRYZ tumour 20599803
ENSG00000116791 CRYZ cancer 20630857
ENSG00000116791 CRYZ pancreatic cancer 20966810
ENSG00000116791 CRYZ cancer 21070139
ENSG00000116791 CRYZ prostate cancer 21176082
ENSG00000116791 CRYZ cancer 21187465
ENSG00000116791 CRYZ bladder cancer 21253823
ENSG00000116791 CRYZ cancers 21369766
ENSG00000116791 CRYZ gastric cancer 21518531
ENSG00000116791 CRYZ cancer 21843634
ENSG00000116791 CRYZ Cancer 21904446
ENSG00000116791 CRYZ breast cancer 22072621
ENSG00000116791 CRYZ tumors 22266358
ENSG00000116791 CRYZ colorectal cancer 22306249
ENSG00000116791 CRYZ cancer 22387672
ENSG00000116791 CRYZ tumour 22696703
ENSG00000116791 CRYZ gastric cancer 22911602
ENSG00000116791 CRYZ breast cancer 22960073
ENSG00000116791 CRYZ tumor 22989153
ENSG00000116791 CRYZ Prostate Cancer 23109831
ENSG00000116791 CRYZ lung cancer 23110137
ENSG00000116791 CRYZ cancer 23198810
ENSG00000116791 CRYZ Lung Cancer 23467445
ENSG00000116791 CRYZ tumor 23635904
ENSG00000116791 CRYZ cancer 23662135
ENSG00000116791 CRYZ cancer 23725139
ENSG00000116791 CRYZ cancer 23803694
ENSG00000116791 CRYZ lung cancer 23852860
ENSG00000116791 CRYZ cancer 23860519
ENSG00000116791 CRYZ cancer 23865001
ENSG00000116791 CRYZ cancer 23883585
ENSG00000116791 CRYZ cancers 23886315
ENSG00000116791 CRYZ cancer 23918565
ENSG00000116791 CRYZ bladder cancer 24035474
ENSG00000116791 CRYZ esophageal cancer 24142529
ENSG00000116791 CRYZ tumor 24161164
ENSG00000116791 CRYZ urinary bladder cancer 24219772
ENSG00000116791 CRYZ tumor 24241058
ENSG00000116791 CRYZ cancer 24244442
ENSG00000116791 CRYZ cancers 24460787
ENSG00000116791 CRYZ renal cancer 24462458
ENSG00000116791 CRYZ AML 24474393
ENSG00000116791 CRYZ lung cancer 24505400
ENSG00000116791 CRYZ gastric cancer 24716985
ENSG00000116791 CRYZ cancer 24819061
ENSG00000116791 CRYZ tumor 25143260
ENSG00000116791 CRYZ cancer 25179580
ENSG00000116791 CRYZ cancers 25231218
ENSG00000116791 CRYZ breast cancer 25245543
ENSG00000116791 CRYZ cancers 25281270
ENSG00000116791 CRYZ cancer 25448047
ENSG00000116791 CRYZ cancer 25540870
ENSG00000116791 CRYZ cancer 25590809
ENSG00000116791 CRYZ lung cancer 25729241
ENSG00000116791 CRYZ tumour 25756848
ENSG00000116791 CRYZ tumor 25880877
ENSG00000116791 CRYZ liver cancer 26415823
ENSG00000116791 CRYZ cancer 26444384
ENSG00000116791 CRYZ cancer 26453163
ENSG00000116791 CRYZ tumors 26462257
ENSG00000116791 CRYZ cancer 26555574
ENSG00000116791 CRYZ tumors 26596252
ENSG00000116791 CRYZ tumor 26602448
ENSG00000116791 CRYZ tumors 26630137
ENSG00000116791 CRYZ cancer 26838129
ENSG00000116791 CRYZ cancer 26893163
ENSG00000116791 CRYZ Tumor 27048660
ENSG00000116791 CRYZ cancers 27196777
ENSG00000116791 CRYZ tumor 27213353
ENSG00000116791 CRYZ cancer 27515817
ENSG00000116791 CRYZ laryngeal cancer 27840932
ENSG00000116791 CRYZ cancer 27923905
ENSG00000116791 CRYZ tumor 27959364
ENSG00000116791 CRYZ tumors 27975234
ENSG00000116791 CRYZ esophageal cancer 28203294
ENSG00000116791 CRYZ cancer 28236663
ENSG00000116791 CRYZ cancer 28240865
ENSG00000116791 CRYZ cervical cancer 28498397
ENSG00000116791 CRYZ cancer 28524357
ENSG00000116791 CRYZ tumors 28580145
ENSG00000116791 CRYZ Pancreatic Cancer 28639725
ENSG00000116791 CRYZ ovarian cancer 28977855
ENSG00000116791 CRYZ cancer 29434949
ENSG00000116791 CRYZ cancer 29567345
ENSG00000116791 CRYZ esophageal cancer 29652514
ENSG00000116791 CRYZ Cancer 29712428
ENSG00000116791 CRYZ Cancer 29847952
ENSG00000116791 CRYZ cancer 29914576
ENSG00000116791 CRYZ prostate cancer 30009389
ENSG00000116791 CRYZ cancer 30009918
ENSG00000116791 CRYZ cancer 30034236
ENSG00000116791 CRYZ Skin Tumors 30385611
ENSG00000116791 CRYZ cancer 30458279
ENSG00000116791 CRYZ cancer 30487423
ENSG00000116791 CRYZ Non-Small-Cell Lung Cancer 30508483
ENSG00000116791 CRYZ cancer 30612064
ENSG00000116791 CRYZ cancer 30657321
ENSG00000116791 CRYZ cancer 30806580
ENSG00000116791 CRYZ liver cancers 30867140
ENSG00000116791 CRYZ tumor 30876568
ENSG00000116791 CRYZ colon cancer 31018491
ENSG00000116791 CRYZ cancer 31322268
ENSG00000116791 CRYZ cancer 31327676
ENSG00000116791 CRYZ tumor 31397998
ENSG00000116791 CRYZ Cancer 31480790
ENSG00000116791 CRYZ cancer 31514018
ENSG00000116791 CRYZ prostate cancer 31533842
ENSG00000116791 CRYZ cancer 31563996
ENSG00000116791 CRYZ cancer 31655637
ENSG00000116791 CRYZ cancer 31790893
ENSG00000116791 CRYZ tumors 31814180
ENSG00000116791 CRYZ liver cancer 31842909
ENSG00000116791 CRYZ tumor 31909204
ENSG00000116791 CRYZ prostate cancer 31925267
ENSG00000116791 CRYZ tumors 31935063
ENSG00000116791 CRYZ tumor 31968140
ENSG00000116791 CRYZ breast cancer 7565631
ENSG00000116791 CRYZ cancer 7685584
ENSG00000116791 CRYZ colon cancer 7812966
ENSG00000116791 CRYZ kidney cancer 8313512
ENSG00000116791 CRYZ tumor 8473041
ENSG00000116791 CRYZ lung cancer 8528266
ENSG00000116791 CRYZ tumor 8614004
ENSG00000116791 CRYZ tumor 8944071
ENSG00000116791 CRYZ Lung cancer 9037558
ENSG00000116791 CRYZ cancer 9328142
ENSG00000116791 CRYZ tumors 9659582
ENSG00000116791 CRYZ cancer 9696930
ENSG00000116791 CRYZ lung tumors 9748120
ENSG00000116791 CRYZ tumor 9815750
ENSG00000116791 CRYZ tumors 9865924
ENSG00000116791 CRYZ nonsmall cell lung cancer 9871615
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000116791 CRYZ MESO 0.0026 low
ENSG00000116791 CRYZ PAAD 0.0039 high
ENSG00000116791 CRYZ UCEC 0.0039 high
ENSG00000116791 CRYZ ACC 0.0018 low
ENSG00000116791 CRYZ LUSC 0.012 high
ENSG00000116791 CRYZ KICH 0.0095 low
ENSG00000116791 CRYZ PCPG 0.0022 high
ENSG00000116791 CRYZ THYM 0.011 high
ENSG00000116791 CRYZ BRCA 0.031 low
ENSG00000116791 CRYZ GBM 0.0035 high
ENSG00000116791 CRYZ SKCM 0.0021 low
ENSG00000116791 CRYZ CESC 0.027 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000116791 CRYZ LUAD Del 1.916279 0.066512 0.307242 0.255814
ENSG00000116791 CRYZ COAD Del 5.138082 0.081619 0.420526 0.292683
ENSG00000116791 CRYZ SKCM Del 0.778273 0.067850 0.418679 0.196185
ENSG00000116791 CRYZ HNSC Del 0.742351 0.054755 0.338052 0.174330
ENSG00000116791 CRYZ PCPG Del 10.762276 0.198486 0.684133 0.734568
ENSG00000116791 CRYZ BRCA Del 1.112629 0.067365 0.386517 0.301852
ENSG00000116791 CRYZ MESO Del 2.507062 0.195375 0.557957 0.275862