Ensembl ID ENSG00000116350 Gene ID 6429 Accession 10786
Gene Symbol SRSF4 Alias SFRS4;SRP75 Full Name serine and arginine rich splicing factor 4
Position 1 : 29147743 - 29181900 Length 34158 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary Enables RNA binding activity. Involved in negative regulation of mRNA splicing, via spliceosome. Located in nuclear speck. Biomarker of Down syndrome; acute myeloid leukemia; clear cell renal cell carcinoma; and colon adenocarcinoma. [provided by Alliance of Genome Resources, Apr 2022]

ENSG00000116350 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000116350 SRSF4 0.41 1.48e-19 KIRC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000116350 SRSF4 AML 22722453
ENSG00000116350 SRSF4 AML 29789787
ENSG00000116350 SRSF4 cancer 30881377
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000116350 SRSF4 MESO 0.04 high
ENSG00000116350 SRSF4 SARC 0.0023 high
ENSG00000116350 SRSF4 STAD 0.0071 low
ENSG00000116350 SRSF4 UVM 0.031 high
ENSG00000116350 SRSF4 UCEC 0.0024 high
ENSG00000116350 SRSF4 THCA 0.007 low
ENSG00000116350 SRSF4 ACC 0.00096 high
ENSG00000116350 SRSF4 HNSC 0.0046 low
ENSG00000116350 SRSF4 READ 0.033 low
ENSG00000116350 SRSF4 KICH 0.0033 high
ENSG00000116350 SRSF4 LUAD 0.019 low
ENSG00000116350 SRSF4 PCPG 0.015 low
ENSG00000116350 SRSF4 THYM 0.0016 low
ENSG00000116350 SRSF4 BRCA 0.0056 low
ENSG00000116350 SRSF4 COAD 0.016 high
ENSG00000116350 SRSF4 BLCA 0.00024 low
ENSG00000116350 SRSF4 LAML 0.019 high
ENSG00000116350 SRSF4 GBM 0.049 high
ENSG00000116350 SRSF4 LIHC 0.0012 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000116350 SRSF4 CHOL Del 16.374748 0.914238 0.679149 0.722222
ENSG00000116350 SRSF4 LUSC Del 2.268777 0.086223 0.379445 0.423154
ENSG00000116350 SRSF4 KIRP Del 4.900289 0.064282 0.586122 0.170139
ENSG00000116350 SRSF4 READ Del 8.503317 0.208656 0.444834 0.454545
ENSG00000116350 SRSF4 COAD Del 17.028316 0.151475 0.449778 0.354767
ENSG00000116350 SRSF4 PAAD Del 2.899060 0.084729 0.351449 0.342391
ENSG00000116350 SRSF4 ESCA Del 1.225573 0.111795 0.347440 0.364130
ENSG00000116350 SRSF4 LIHC Del 15.691224 0.206874 0.537625 0.375676
ENSG00000116350 SRSF4 PCPG Del 1.786254 0.080865 0.673325 0.623457
ENSG00000116350 SRSF4 BRCA Del 18.169544 0.142950 0.408237 0.383333
ENSG00000116350 SRSF4 STAD Del 5.095722 0.109247 0.357074 0.258503
ENSG00000116350 SRSF4 UCEC Del 8.916915 0.113287 0.503394 0.131725
ENSG00000116350 SRSF4 MESO Del 1.760734 0.166753 0.558487 0.241379
ENSG00000116350 SRSF4 KIRC Del 5.046032 0.046956 0.418262 0.176136
ENSG00000116350 SRSF4 UVM Del 1.063142 0.071726 0.771498 0.312500
ENSG00000116350 SRSF4 OV Del 18.365617 0.370046 0.553483 0.376511