Ensembl ID ENSG00000116221 Gene ID 51253 Accession 14034
Gene Symbol MRPL37 Alias L2mt;mL37;L37mt;MRPL2;RPML2;MRP-L2;MRP-L37 Full Name mitochondrial ribosomal protein L37
Position 1 : 54200167 - 54225464 Length 25298 bases Strand Plus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]

ENSG00000116221 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000116221 MRPL37 0.52 3.24e-17 BRCA
ENSG00000116221 MRPL37 0.58 3.61e-12 COAD
ENSG00000116221 MRPL37 1.05 2.47e-45 LUSC
ENSG00000116221 MRPL37 0.49 7.37e-15 PRAD
ENSG00000116221 MRPL37 0.87 6.23e-19 UCEC
ENSG00000116221 MRPL37 0.67 2.23e-20 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000116221 MRPL37 MESO 1e-04 high
ENSG00000116221 MRPL37 SARC 0.00095 high
ENSG00000116221 MRPL37 STAD 0.0017 low
ENSG00000116221 MRPL37 PAAD 0.012 high
ENSG00000116221 MRPL37 UCEC 0.002 high
ENSG00000116221 MRPL37 ACC 0.0016 high
ENSG00000116221 MRPL37 LUSC 0.0022 low
ENSG00000116221 MRPL37 READ 0.0011 low
ENSG00000116221 MRPL37 KIRP 0.0025 high
ENSG00000116221 MRPL37 KICH 0.0077 high
ENSG00000116221 MRPL37 LUAD 0.0042 high
ENSG00000116221 MRPL37 COAD 0.0022 low
ENSG00000116221 MRPL37 ESCA 0.026 high
ENSG00000116221 MRPL37 DLBC 0.026 low
ENSG00000116221 MRPL37 KIRC 0.003 low
ENSG00000116221 MRPL37 BLCA 0.016 high
ENSG00000116221 MRPL37 LAML 0.011 high
ENSG00000116221 MRPL37 SKCM 0.00013 high
ENSG00000116221 MRPL37 LIHC 0.00017 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000116221 MRPL37 CHOL Del 1.135584 0.246604 0.630660 0.277778
ENSG00000116221 MRPL37 COAD Del 0.754915 0.042970 0.394951 0.261641
ENSG00000116221 MRPL37 PCPG Del 8.546986 0.174427 0.685440 0.722222
ENSG00000116221 MRPL37 UVM Del 1.796122 0.105558 0.808820 0.287500
ENSG00000116221 MRPL37 OV Amp 1.335699 0.352098 0.619455 0.383420