Ensembl ID ENSG00000116120 Gene ID 10056 Accession 17800
Gene Symbol FARSB Alias FRSB;RJBS;PheHB;PheRS;FARSLB;RILDBC;HSPC173;NEDBLLA;RILDBC1 Full Name phenylalanyl-tRNA synthetase subunit beta
Position 2 : 222566899 - 222656092 Length 89194 bases Strand Minus strand
Status Confidence Main interacting RNAstRNARBP type Canonical_RBPs
Summary This gene encodes a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalytic alpha subunits. In the presence of ATP, this tetramer is responsible for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA. A pseudogene located on chromosome 10 has been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

ENSG00000116120 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000116120 FARSB 0.38 9.11e-16 BRCA
ENSG00000116120 FARSB 0.63 2.45e-17 COAD
ENSG00000116120 FARSB 1.16 6.19e-52 LUSC
ENSG00000116120 FARSB 0.38 3.25e-12 PRAD
ENSG00000116120 FARSB 0.54 1.77e-12 LIHC
ENSG00000116120 FARSB 0.80 7.49e-30 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000116120 FARSB MESO 0.005 high
ENSG00000116120 FARSB SARC 0.00052 high
ENSG00000116120 FARSB CHOL 0.0053 low
ENSG00000116120 FARSB UVM 0.00096 high
ENSG00000116120 FARSB PAAD 0.0077 high
ENSG00000116120 FARSB UCEC 0.001 low
ENSG00000116120 FARSB LUSC 0.044 low
ENSG00000116120 FARSB KIRP 0.00037 high
ENSG00000116120 FARSB KICH 0.019 high
ENSG00000116120 FARSB LUAD 0.0012 high
ENSG00000116120 FARSB PCPG 0.015 high
ENSG00000116120 FARSB BRCA 0.0029 high
ENSG00000116120 FARSB KIRC 0.00012 high
ENSG00000116120 FARSB TGCT 0.016 high
ENSG00000116120 FARSB CESC 0.0039 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000116120 FARSB LUSC Del 15.633339 0.184548 0.390384 0.297405
ENSG00000116120 FARSB CESC Del 34.959749 0.352320 0.528006 0.413559
ENSG00000116120 FARSB KIRP Amp 1.259300 0.069152 0.554374 0.163194
ENSG00000116120 FARSB KIRP Del 2.440554 0.043607 0.632629 0.041667
ENSG00000116120 FARSB SARC Del 4.061563 0.200101 0.515704 0.342412
ENSG00000116120 FARSB ESCA Del 2.227918 0.138862 0.378461 0.239130
ENSG00000116120 FARSB SKCM Del 0.647561 0.065490 0.401953 0.179837
ENSG00000116120 FARSB HNSC Del 22.822267 0.186456 0.393144 0.291188
ENSG00000116120 FARSB BLCA Del 24.857131 0.279685 0.439606 0.477941
ENSG00000116120 FARSB BRCA Del 1.409434 0.069971 0.348263 0.259259
ENSG00000116120 FARSB UCEC Del 0.802444 0.049011 0.440303 0.079777
ENSG00000116120 FARSB KIRC Del 9.897250 0.066230 0.538731 0.087121
ENSG00000116120 FARSB OV Del 1.528163 0.193531 0.488604 0.250432