Ensembl ID
ENSG00000116120
Gene ID
10056
Accession
17800
Gene Symbol
FARSB
Alias
FRSB;RJBS;PheHB;PheRS;FARSLB;RILDBC;HSPC173;NEDBLLA;RILDBC1
Full Name
phenylalanyl-tRNA synthetase subunit beta
Position
2 : 222566899 - 222656092
Length
89194 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs tRNA RBP type
Canonical_RBPs
Summary
This gene encodes a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalytic alpha subunits. In the presence of ATP, this tetramer is responsible for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA. A pseudogene located on chromosome 10 has been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
ENSG00000116120 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000116120
FARSB
0.38
9.11e-16
BRCA
ENSG00000116120
FARSB
0.63
2.45e-17
COAD
ENSG00000116120
FARSB
1.16
6.19e-52
LUSC
ENSG00000116120
FARSB
0.38
3.25e-12
PRAD
ENSG00000116120
FARSB
0.54
1.77e-12
LIHC
ENSG00000116120
FARSB
0.80
7.49e-30
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000116120
FARSB
MESO
0.005
high
show
ENSG00000116120
FARSB
SARC
0.00052
high
show
ENSG00000116120
FARSB
CHOL
0.0053
low
show
ENSG00000116120
FARSB
UVM
0.00096
high
show
ENSG00000116120
FARSB
PAAD
0.0077
high
show
ENSG00000116120
FARSB
UCEC
0.001
low
show
ENSG00000116120
FARSB
LUSC
0.044
low
show
ENSG00000116120
FARSB
KIRP
0.00037
high
show
ENSG00000116120
FARSB
KICH
0.019
high
show
ENSG00000116120
FARSB
LUAD
0.0012
high
show
ENSG00000116120
FARSB
PCPG
0.015
high
show
ENSG00000116120
FARSB
BRCA
0.0029
high
show
ENSG00000116120
FARSB
KIRC
0.00012
high
show
ENSG00000116120
FARSB
TGCT
0.016
high
show
ENSG00000116120
FARSB
CESC
0.0039
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000116120
FARSB
LUSC
Del
15.633339
0.184548
0.390384
0.297405
ENSG00000116120
FARSB
CESC
Del
34.959749
0.352320
0.528006
0.413559
ENSG00000116120
FARSB
KIRP
Amp
1.259300
0.069152
0.554374
0.163194
ENSG00000116120
FARSB
KIRP
Del
2.440554
0.043607
0.632629
0.041667
ENSG00000116120
FARSB
SARC
Del
4.061563
0.200101
0.515704
0.342412
ENSG00000116120
FARSB
ESCA
Del
2.227918
0.138862
0.378461
0.239130
ENSG00000116120
FARSB
SKCM
Del
0.647561
0.065490
0.401953
0.179837
ENSG00000116120
FARSB
HNSC
Del
22.822267
0.186456
0.393144
0.291188
ENSG00000116120
FARSB
BLCA
Del
24.857131
0.279685
0.439606
0.477941
ENSG00000116120
FARSB
BRCA
Del
1.409434
0.069971
0.348263
0.259259
ENSG00000116120
FARSB
UCEC
Del
0.802444
0.049011
0.440303
0.079777
ENSG00000116120
FARSB
KIRC
Del
9.897250
0.066230
0.538731
0.087121
ENSG00000116120
FARSB
OV
Del
1.528163
0.193531
0.488604
0.250432
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