Ensembl ID ENSG00000116030 Gene ID 7341 Accession 12502
Gene Symbol SUMO1 Alias DAP1;GMP1;PIC1;SMT3;UBL1;OFC10;SENP2;SMT3C;SMT3H3 Full Name small ubiquitin like modifier 1
Position 2 : 202206182 - 202238599 Length 32418 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]

ENSG00000116030 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000116030 SUMO1 0.41 2.69e-23 BRCA
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000116030 SUMO1 tumour 10504575
ENSG00000116030 SUMO1 tumor 11479235
ENSG00000116030 SUMO1 tumor 12621041
ENSG00000116030 SUMO1 tumor 12813045
ENSG00000116030 SUMO1 cancer 15123625
ENSG00000116030 SUMO1 Wilms' tumor 15520190
ENSG00000116030 SUMO1 tumor 16563226
ENSG00000116030 SUMO1 breast cancer 17079232
ENSG00000116030 SUMO1 tumor 17284251
ENSG00000116030 SUMO1 tumor 17671677
ENSG00000116030 SUMO1 tumor 17803295
ENSG00000116030 SUMO1 prostate cancer 17932034
ENSG00000116030 SUMO1 tumor 18025037
ENSG00000116030 SUMO1 breast cancer 18179684
ENSG00000116030 SUMO1 tumor 18492669
ENSG00000116030 SUMO1 tumour 18710513
ENSG00000116030 SUMO1 liver cancer 19384898
ENSG00000116030 SUMO1 tumor 19859084
ENSG00000116030 SUMO1 tumor 20300531
ENSG00000116030 SUMO1 tumor 20458745
ENSG00000116030 SUMO1 prostate cancer 20551310
ENSG00000116030 SUMO1 cancer 20616338
ENSG00000116030 SUMO1 cancer 21123177
ENSG00000116030 SUMO1 GBM 21317457
ENSG00000116030 SUMO1 tumor 21606198
ENSG00000116030 SUMO1 cancer 21646468
ENSG00000116030 SUMO1 tumor 21786080
ENSG00000116030 SUMO1 breast cancer 22586270
ENSG00000116030 SUMO1 tumour 22713753
ENSG00000116030 SUMO1 prostate cancer 23044371
ENSG00000116030 SUMO1 tumor 23078246
ENSG00000116030 SUMO1 tumour 23417988
ENSG00000116030 SUMO1 colon cancer 23640307
ENSG00000116030 SUMO1 gastric cancer 23996296
ENSG00000116030 SUMO1 breast cancer 24068740
ENSG00000116030 SUMO1 pancreatic cancer 24654937
ENSG00000116030 SUMO1 lung cancer 24691972
ENSG00000116030 SUMO1 tumor 24777122
ENSG00000116030 SUMO1 cancer 24819975
ENSG00000116030 SUMO1 tumor 24953629
ENSG00000116030 SUMO1 prostate cancer 25027693
ENSG00000116030 SUMO1 lip cancer 25241153
ENSG00000116030 SUMO1 AML 25448401
ENSG00000116030 SUMO1 tumor 25823821
ENSG00000116030 SUMO1 oral cancer 25901414
ENSG00000116030 SUMO1 prostate cancer 26202067
ENSG00000116030 SUMO1 Endometrial Cancer 26222483
ENSG00000116030 SUMO1 cancer 26244656
ENSG00000116030 SUMO1 breast cancer 26403314
ENSG00000116030 SUMO1 colon cancer 26416353
ENSG00000116030 SUMO1 tumors 26476082
ENSG00000116030 SUMO1 cervical cancer 26642330
ENSG00000116030 SUMO1 liver tumor 26993772
ENSG00000116030 SUMO1 tumor 27072586
ENSG00000116030 SUMO1 endometrial cancer 27230680
ENSG00000116030 SUMO1 tumors 27449295
ENSG00000116030 SUMO1 tumor 27741516
ENSG00000116030 SUMO1 Gastric Cancer 28222440
ENSG00000116030 SUMO1 liver cancer 28240261
ENSG00000116030 SUMO1 cancer 28510446
ENSG00000116030 SUMO1 GBM 28785061
ENSG00000116030 SUMO1 tumor 29020972
ENSG00000116030 SUMO1 tumor 29060933
ENSG00000116030 SUMO1 endometrial cancer 29275599
ENSG00000116030 SUMO1 liver cancer 29393359
ENSG00000116030 SUMO1 gastric cancer 29484374
ENSG00000116030 SUMO1 tumor 29682099
ENSG00000116030 SUMO1 cancer 29713182
ENSG00000116030 SUMO1 non-small cell lung cancer 30043429
ENSG00000116030 SUMO1 tumor 30226577
ENSG00000116030 SUMO1 cancer 30333879
ENSG00000116030 SUMO1 small cell lung cancer 30393970
ENSG00000116030 SUMO1 breast cancer 30940449
ENSG00000116030 SUMO1 breast cancer 30948704
ENSG00000116030 SUMO1 GBM 30991648
ENSG00000116030 SUMO1 tumor 31125786
ENSG00000116030 SUMO1 cancers 31422931
ENSG00000116030 SUMO1 tumor 31489957
ENSG00000116030 SUMO1 breast cancer 31578236
ENSG00000116030 SUMO1 tumor 31616295
ENSG00000116030 SUMO1 cancer 31660066
ENSG00000116030 SUMO1 cancer 31753025
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000116030 SUMO1 STAD 0.02 low
ENSG00000116030 SUMO1 CHOL 0.011 high
ENSG00000116030 SUMO1 UVM 0.037 high
ENSG00000116030 SUMO1 PAAD 0.0077 high
ENSG00000116030 SUMO1 UCEC 0.0028 high
ENSG00000116030 SUMO1 THCA 0.028 low
ENSG00000116030 SUMO1 LGG 0.0021 high
ENSG00000116030 SUMO1 HNSC 0.009 high
ENSG00000116030 SUMO1 KIRP 0.0011 high
ENSG00000116030 SUMO1 LUAD 0.018 high
ENSG00000116030 SUMO1 PCPG 0.0015 high
ENSG00000116030 SUMO1 THYM 0.034 low
ENSG00000116030 SUMO1 BRCA 0.033 high
ENSG00000116030 SUMO1 ESCA 0.019 high
ENSG00000116030 SUMO1 OV 0.0023 low
ENSG00000116030 SUMO1 KIRC 0.03 low
ENSG00000116030 SUMO1 SKCM 0.0015 low
ENSG00000116030 SUMO1 CESC 0.004 low
ENSG00000116030 SUMO1 LIHC 0.015 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000116030 SUMO1 LUSC Del 1.480368 0.076715 0.335717 0.171657
ENSG00000116030 SUMO1 CESC Del 12.751275 0.199281 0.494166 0.284746
ENSG00000116030 SUMO1 KIRP Amp 1.259300 0.072829 0.577568 0.170139
ENSG00000116030 SUMO1 KIRP Del 0.809889 0.027818 0.594392 0.027778
ENSG00000116030 SUMO1 HNSC Del 9.231639 0.117391 0.349457 0.208812
ENSG00000116030 SUMO1 BLCA Del 3.363050 0.115960 0.379050 0.360294
ENSG00000116030 SUMO1 KIRC Del 0.898700 0.026041 0.543163 0.049242