Ensembl ID ENSG00000116001 Gene ID 7072 Accession 11802
Gene Symbol TIA1 Alias WDM;ALS26;TIA-1 Full Name TIA1 cytotoxic granule associated RNA binding protein
Position 2 : 70209444 - 70248660 Length 39217 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms has been found for this gene. [provided by RefSeq, May 2017]

ENSG00000116001 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000116001 TIA1 0.75 5.69e-20 KIRC
ENSG00000116001 TIA1 0.70 2.70e-17 LUSC
ENSG00000116001 TIA1 0.64 4.98e-14 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000116001 TIA1 tumor 10029454
ENSG00000116001 TIA1 tumor 10233858
ENSG00000116001 TIA1 tumour 10368677
ENSG00000116001 TIA1 tumor 10404082
ENSG00000116001 TIA1 tumor 10504545
ENSG00000116001 TIA1 tumor 10574602
ENSG00000116001 TIA1 tumor 10658910
ENSG00000116001 TIA1 tumours 10838752
ENSG00000116001 TIA1 tumor 11070120
ENSG00000116001 TIA1 tumor 11097373
ENSG00000116001 TIA1 tumor 11107059
ENSG00000116001 TIA1 tumor 11134836
ENSG00000116001 TIA1 tumors 11244989
ENSG00000116001 TIA1 tumor 11368448
ENSG00000116001 TIA1 tumour 11699214
ENSG00000116001 TIA1 tumour 11723833
ENSG00000116001 TIA1 tumor 11731515
ENSG00000116001 TIA1 tumour 11748644
ENSG00000116001 TIA1 tumor 11866963
ENSG00000116001 TIA1 tumor 11869547
ENSG00000116001 TIA1 tumor 12184377
ENSG00000116001 TIA1 tumor 12434133
ENSG00000116001 TIA1 tumor 12456216
ENSG00000116001 TIA1 Tumor 12483012
ENSG00000116001 TIA1 tumor 12768754
ENSG00000116001 TIA1 Colon cancer 12885872
ENSG00000116001 TIA1 tumor 12949814
ENSG00000116001 TIA1 tumor 14649966
ENSG00000116001 TIA1 tumor 14684957
ENSG00000116001 TIA1 tumor 14991542
ENSG00000116001 TIA1 Tumor 15168777
ENSG00000116001 TIA1 tumor 15223661
ENSG00000116001 TIA1 cancer 15330177
ENSG00000116001 TIA1 tumor 15660281
ENSG00000116001 TIA1 tumor 15811123
ENSG00000116001 TIA1 tumor 15824085
ENSG00000116001 TIA1 tumor 15863868
ENSG00000116001 TIA1 tumor 16021507
ENSG00000116001 TIA1 tumor 16123584
ENSG00000116001 TIA1 tumor 16189700
ENSG00000116001 TIA1 tumor 16236613
ENSG00000116001 TIA1 tumor 17103008
ENSG00000116001 TIA1 tumour 17456059
ENSG00000116001 TIA1 cervical cancer 17598517
ENSG00000116001 TIA1 tumor 17851553
ENSG00000116001 TIA1 tumor 18043044
ENSG00000116001 TIA1 Tumor 18923710
ENSG00000116001 TIA1 tumor 18959781
ENSG00000116001 TIA1 tumor 19096012
ENSG00000116001 TIA1 tumour 19126565
ENSG00000116001 TIA1 tumor 19491267
ENSG00000116001 TIA1 tumor 19640585
ENSG00000116001 TIA1 ovarian cancer 19641607
ENSG00000116001 TIA1 tumor 19860626
ENSG00000116001 TIA1 tumor 20065852
ENSG00000116001 TIA1 tumor 20068100
ENSG00000116001 TIA1 tumor 20442639
ENSG00000116001 TIA1 tumor 20495447
ENSG00000116001 TIA1 tumor 20664940
ENSG00000116001 TIA1 tumor 20845062
ENSG00000116001 TIA1 cancer 20980400
ENSG00000116001 TIA1 Colorectal Cancer 21179245
ENSG00000116001 TIA1 tumours 21284605
ENSG00000116001 TIA1 tumor 21347286
ENSG00000116001 TIA1 tumor 21352347
ENSG00000116001 TIA1 tumor 21542892
ENSG00000116001 TIA1 tumor 21695097
ENSG00000116001 TIA1 tumor 21713364
ENSG00000116001 TIA1 tumour 22035150
ENSG00000116001 TIA1 tumors 22151962
ENSG00000116001 TIA1 tumor 22177246
ENSG00000116001 TIA1 tumor 22192806
ENSG00000116001 TIA1 Tumors 22282309
ENSG00000116001 TIA1 liver tumor 22401581
ENSG00000116001 TIA1 tumor 22829038
ENSG00000116001 TIA1 tumour 22859396
ENSG00000116001 TIA1 tumor 22931631
ENSG00000116001 TIA1 tumour 23302373
ENSG00000116001 TIA1 cancer 23642182
ENSG00000116001 TIA1 tumor 23773344
ENSG00000116001 TIA1 tumor 23826590
ENSG00000116001 TIA1 Tumor 23900161
ENSG00000116001 TIA1 tumor 23958352
ENSG00000116001 TIA1 tumors 24190978
ENSG00000116001 TIA1 tumors 24376535
ENSG00000116001 TIA1 tumor 24439229
ENSG00000116001 TIA1 tumor 25197351
ENSG00000116001 TIA1 colon cancer 25224594
ENSG00000116001 TIA1 tumors 25225843
ENSG00000116001 TIA1 tumor 25289105
ENSG00000116001 TIA1 tumor 25337299
ENSG00000116001 TIA1 tumor 25425213
ENSG00000116001 TIA1 tumours 25556356
ENSG00000116001 TIA1 tumor 25609202
ENSG00000116001 TIA1 rectal cancer 25609852
ENSG00000116001 TIA1 tumor 25678188
ENSG00000116001 TIA1 tumor 25741594
ENSG00000116001 TIA1 tumor 25797890
ENSG00000116001 TIA1 tumor 26067141
ENSG00000116001 TIA1 tumor 26126576
ENSG00000116001 TIA1 Tumor 26181557
ENSG00000116001 TIA1 tumors 26256881
ENSG00000116001 TIA1 tumor 26451326
ENSG00000116001 TIA1 tumor 26617911
ENSG00000116001 TIA1 tumor 26872300
ENSG00000116001 TIA1 tumor 26958940
ENSG00000116001 TIA1 tumor 26981243
ENSG00000116001 TIA1 tumor 27196451
ENSG00000116001 TIA1 ovarian cancer 27470997
ENSG00000116001 TIA1 tumor 27612448
ENSG00000116001 TIA1 tumors 28056296
ENSG00000116001 TIA1 cancer 28174264
ENSG00000116001 TIA1 tumor 28257633
ENSG00000116001 TIA1 tumors 28344870
ENSG00000116001 TIA1 cancers 28575488
ENSG00000116001 TIA1 tumor 29137032
ENSG00000116001 TIA1 tumor 29245256
ENSG00000116001 TIA1 tumor 29496454
ENSG00000116001 TIA1 tumor 30100756
ENSG00000116001 TIA1 gastric cancer 30144499
ENSG00000116001 TIA1 tumour 30151671
ENSG00000116001 TIA1 tumor 30269475
ENSG00000116001 TIA1 tumor 30641639
ENSG00000116001 TIA1 cancer 30788036
ENSG00000116001 TIA1 tumor 30918141
ENSG00000116001 TIA1 tumor 30931288
ENSG00000116001 TIA1 tumor 31366386
ENSG00000116001 TIA1 tumor 31371036
ENSG00000116001 TIA1 tumor 31440515
ENSG00000116001 TIA1 cancer 31555352
ENSG00000116001 TIA1 tumor 31741762
ENSG00000116001 TIA1 tumor 8477207
ENSG00000116001 TIA1 tumor 9255261
ENSG00000116001 TIA1 tumour 9349234
ENSG00000116001 TIA1 tumour 9359478
ENSG00000116001 TIA1 tumour 9363445
ENSG00000116001 TIA1 tumour 9496260
ENSG00000116001 TIA1 tumor 9717820
ENSG00000116001 TIA1 tumor 9777980
ENSG00000116001 TIA1 tumor 9778108
ENSG00000116001 TIA1 DLBCLs 9846961
ENSG00000116001 TIA1 tumour 9870150
ENSG00000116001 TIA1 tumor 9949180
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000116001 TIA1 UVM 0.012 high
ENSG00000116001 TIA1 PAAD 0.045 low
ENSG00000116001 TIA1 LGG 0.013 high
ENSG00000116001 TIA1 LUSC 0.0054 low
ENSG00000116001 TIA1 HNSC 0.0026 low
ENSG00000116001 TIA1 READ 0.017 low
ENSG00000116001 TIA1 LUAD 0.0015 low
ENSG00000116001 TIA1 THYM 0.0011 low
ENSG00000116001 TIA1 UCS 0.023 low
ENSG00000116001 TIA1 ESCA 0.032 high
ENSG00000116001 TIA1 PRAD 0.038 high
ENSG00000116001 TIA1 LAML 0.0011 low
ENSG00000116001 TIA1 GBM 0.0035 low
ENSG00000116001 TIA1 SKCM 0.00014 low
ENSG00000116001 TIA1 LIHC 0.0072 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency