Ensembl ID ENSG00000115875 Gene ID 6432 Accession 10789
Gene Symbol SRSF7 Alias 9G8;AAG3;SFRS7 Full Name serine and arginine rich splicing factor 7
Position 2 : 38743599 - 38751494 Length 7896 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an N-terminal RNA recognition motif (RRM) for binding RNA and a C-terminal RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2018]

ENSG00000115875 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000115875 SRSF7 0.58 1.42e-18 COAD
ENSG00000115875 SRSF7 -1.2 1.34e-29 KICH
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000115875 SRSF7 AML 22722453
ENSG00000115875 SRSF7 breast tumors 26930004
ENSG00000115875 SRSF7 cancer 27282379
ENSG00000115875 SRSF7 colon cancer 27644562
ENSG00000115875 SRSF7 renal cancer 27664584
ENSG00000115875 SRSF7 tumors 29317634
ENSG00000115875 SRSF7 lung cancer 29556298
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000115875 SRSF7 SARC 0.0094 high
ENSG00000115875 SRSF7 STAD 0.011 low
ENSG00000115875 SRSF7 UVM 4e-04 high
ENSG00000115875 SRSF7 PAAD 0.0047 low
ENSG00000115875 SRSF7 LUSC 0.015 low
ENSG00000115875 SRSF7 HNSC 0.024 high
ENSG00000115875 SRSF7 READ 0.028 low
ENSG00000115875 SRSF7 KIRP 0.012 high
ENSG00000115875 SRSF7 KICH 0.0017 high
ENSG00000115875 SRSF7 LUAD 0.039 low
ENSG00000115875 SRSF7 PCPG 0.0069 high
ENSG00000115875 SRSF7 THYM 0.0081 low
ENSG00000115875 SRSF7 UCS 0.045 low
ENSG00000115875 SRSF7 ESCA 0.002 high
ENSG00000115875 SRSF7 DLBC 0.027 low
ENSG00000115875 SRSF7 KIRC 5e-04 high
ENSG00000115875 SRSF7 PRAD 0.022 low
ENSG00000115875 SRSF7 BLCA 0.0065 low
ENSG00000115875 SRSF7 GBM 0.027 low
ENSG00000115875 SRSF7 CESC 0.0013 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000115875 SRSF7 TGCT Amp 1.710327 0.164975 0.453932 0.393333
ENSG00000115875 SRSF7 PRAD Del 0.819005 0.073497 0.444420 0.089431