Ensembl ID
ENSG00000115844
Gene ID
1746
Accession
2915
Gene Symbol
DLX2
Alias
TES1;TES-1
Full Name
distal-less homeobox 2
Position
2 : 172099438 - 172102900
Length
3463 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs N.A. RBP type
Non-canonical_RBPs
Summary
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2. [provided by RefSeq, Jul 2008]
ENSG00000115844 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000115844
DLX2
3.14
2.18e-48
KIRC
ENSG00000115844
DLX2
2.35
7.55e-18
HNSC
ENSG00000115844
DLX2
2.11
9.33e-16
BRCA
ENSG00000115844
DLX2
6.47
1.12e-65
LUSC
ENSG00000115844
DLX2
3.21
1.76e-34
PRAD
ENSG00000115844
DLX2
5.38
2.71e-20
UCEC
ENSG00000115844
DLX2
2.93
5.42e-11
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000115844
DLX2
tumor
12792755
ENSG00000115844
DLX2
tumors
20233874
ENSG00000115844
DLX2
breast cancer
21108812
ENSG00000115844
DLX2
tumors
21169070
ENSG00000115844
DLX2
Cancer
23331016
ENSG00000115844
DLX2
tumor
23674878
ENSG00000115844
DLX2
tumours
23947815
ENSG00000115844
DLX2
cancer
25463899
ENSG00000115844
DLX2
cancer
25904138
ENSG00000115844
DLX2
Cancer
26799321
ENSG00000115844
DLX2
cancer
26833729
ENSG00000115844
DLX2
cancer
27302463
ENSG00000115844
DLX2
prostate cancer
27336609
ENSG00000115844
DLX2
tumor
28459464
ENSG00000115844
DLX2
tumor
28796261
ENSG00000115844
DLX2
endometrial cancer
30850842
ENSG00000115844
DLX2
tumor
31604930
ENSG00000115844
DLX2
tumor
31920462
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000115844
DLX2
MESO
0.00038
high
show
ENSG00000115844
DLX2
SARC
0.00025
high
show
ENSG00000115844
DLX2
UVM
0.00014
high
show
ENSG00000115844
DLX2
PAAD
0.018
low
show
ENSG00000115844
DLX2
UCEC
0.0029
low
show
ENSG00000115844
DLX2
LGG
0.00027
high
show
ENSG00000115844
DLX2
HNSC
0.023
high
show
ENSG00000115844
DLX2
KICH
0.0032
high
show
ENSG00000115844
DLX2
PCPG
0.0099
low
show
ENSG00000115844
DLX2
BRCA
0.05
low
show
ENSG00000115844
DLX2
COAD
0.0072
high
show
ENSG00000115844
DLX2
KIRC
0.0041
high
show
ENSG00000115844
DLX2
BLCA
0.008
high
show
ENSG00000115844
DLX2
LIHC
0.011
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000115844
DLX2
KIRP
Amp
1.259300
0.073776
0.664421
0.177083
ENSG00000115844
DLX2
HNSC
Amp
1.908034
0.145517
0.487764
0.195402
ENSG00000115844
DLX2
PRAD
Del
1.905224
0.087140
0.431868
0.119919
ENSG00000115844
DLX2
OV
Amp
1.787167
0.367481
0.602228
0.416235
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.