Ensembl ID ENSG00000115541 Gene ID 3336 Accession 5269
Gene Symbol HSPE1 Alias EPF;CPN10;GROES;HSP10 Full Name heat shock protein family E (Hsp10) member 1
Position 2 : 197500140 - 197503449 Length 3310 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3.[provided by RefSeq, Feb 2011]

ENSG00000115541 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000115541 HSPE1 1.15 2.34e-60 BRCA
ENSG00000115541 HSPE1 0.87 8.50e-16 COAD
ENSG00000115541 HSPE1 1.65 9.35e-58 LUSC
ENSG00000115541 HSPE1 0.56 7.83e-11 PRAD
ENSG00000115541 HSPE1 0.99 3.77e-12 STAD
ENSG00000115541 HSPE1 1.35 2.62e-26 UCEC
ENSG00000115541 HSPE1 1.28 3.08e-37 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000115541 HSPE1 trophoblastic tumor 10326623
ENSG00000115541 HSPE1 cancer 11033030
ENSG00000115541 HSPE1 colorectal cancer 12907638
ENSG00000115541 HSPE1 tumour 1461992
ENSG00000115541 HSPE1 tumor 15253447
ENSG00000115541 HSPE1 tumours 1537058
ENSG00000115541 HSPE1 tumor 15546885
ENSG00000115541 HSPE1 cancer 15816004
ENSG00000115541 HSPE1 ovarian cancer 16386781
ENSG00000115541 HSPE1 endometrial cancer 16808467
ENSG00000115541 HSPE1 cancer 17048249
ENSG00000115541 HSPE1 cancer 17278877
ENSG00000115541 HSPE1 cancer 17457039
ENSG00000115541 HSPE1 cancer 17552551
ENSG00000115541 HSPE1 tumour 1869285
ENSG00000115541 HSPE1 cancer 19913561
ENSG00000115541 HSPE1 testis cancer 20035552
ENSG00000115541 HSPE1 tumour 21861927
ENSG00000115541 HSPE1 cancer 21969171
ENSG00000115541 HSPE1 tumour 2323098
ENSG00000115541 HSPE1 cancer 23277031
ENSG00000115541 HSPE1 tumor 23589362
ENSG00000115541 HSPE1 cancer 24504108
ENSG00000115541 HSPE1 tumour 24675290
ENSG00000115541 HSPE1 tumor 25075042
ENSG00000115541 HSPE1 cancer 25355063
ENSG00000115541 HSPE1 breast cancer 25454514
ENSG00000115541 HSPE1 colon cancer 25688504
ENSG00000115541 HSPE1 tumour 25949238
ENSG00000115541 HSPE1 tumour 2735162
ENSG00000115541 HSPE1 tumor 27491302
ENSG00000115541 HSPE1 gestational trophoblastic tumors 2823620
ENSG00000115541 HSPE1 tumors 28384045
ENSG00000115541 HSPE1 Cancer 28867797
ENSG00000115541 HSPE1 cancer 29434270
ENSG00000115541 HSPE1 esophageal cancer 29462754
ENSG00000115541 HSPE1 pancreatic cancer 29922073
ENSG00000115541 HSPE1 tumours 29954368
ENSG00000115541 HSPE1 tumor 30112103
ENSG00000115541 HSPE1 cancer 31608236
ENSG00000115541 HSPE1 tumors of germ cell 6399206
ENSG00000115541 HSPE1 testicular germ cell tumors 6859385
ENSG00000115541 HSPE1 tumor 7682025
ENSG00000115541 HSPE1 tumour 8390229
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000115541 HSPE1 MESO 0.012 high
ENSG00000115541 HSPE1 STAD 0.0018 low
ENSG00000115541 HSPE1 UVM 0.0089 high
ENSG00000115541 HSPE1 PAAD 0.012 high
ENSG00000115541 HSPE1 UCEC 0.0051 high
ENSG00000115541 HSPE1 ACC 0.0014 high
ENSG00000115541 HSPE1 HNSC 0.013 high
ENSG00000115541 HSPE1 KICH 0.039 high
ENSG00000115541 HSPE1 LUAD 0.0056 high
ENSG00000115541 HSPE1 PCPG 0.0074 high
ENSG00000115541 HSPE1 THYM 0.021 high
ENSG00000115541 HSPE1 UCS 0.034 high
ENSG00000115541 HSPE1 OV 0.0022 low
ENSG00000115541 HSPE1 DLBC 0.045 low
ENSG00000115541 HSPE1 KIRC 0.033 high
ENSG00000115541 HSPE1 PRAD 0.039 high
ENSG00000115541 HSPE1 BLCA 0.0067 low
ENSG00000115541 HSPE1 LIHC 0.0037 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000115541 HSPE1 CESC Amp 1.353175 0.154654 0.546268 0.166102
ENSG00000115541 HSPE1 KIRP Amp 1.597657 0.090905 0.688447 0.180556
ENSG00000115541 HSPE1 HNSC Amp 0.925170 0.121931 0.483573 0.160920
ENSG00000115541 HSPE1 BLCA Del 0.965128 0.081729 0.362350 0.321078