Ensembl ID ENSG00000115364 Gene ID 9801 Accession 14052
Gene Symbol MRPL19 Alias RLX1;L15mt;L19mt;bL19m;MRPL15;RPML15;MRP-L15;MRP-L19 Full Name mitochondrial ribosomal protein L19
Position 2 : 75646783 - 75690851 Length 44069 bases Strand Plus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]

ENSG00000115364 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000115364 MRPL19 -0.9 7.36e-62 KIRC
ENSG00000115364 MRPL19 0.38 4.00e-15 BRCA
ENSG00000115364 MRPL19 0.91 1.60e-39 LUSC
ENSG00000115364 MRPL19 0.90 3.10e-20 UCEC
ENSG00000115364 MRPL19 -1.2 7.83e-14 CHOL
ENSG00000115364 MRPL19 0.66 8.16e-24 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000115364 MRPL19 breast tumors 15287981
ENSG00000115364 MRPL19 tumour 18042273
ENSG00000115364 MRPL19 tumors 19430294
ENSG00000115364 MRPL19 breast tumors 19544972
ENSG00000115364 MRPL19 tumour 20122155
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000115364 MRPL19 MESO 0.003 high
ENSG00000115364 MRPL19 UVM 0.0068 high
ENSG00000115364 MRPL19 ACC 0.039 high
ENSG00000115364 MRPL19 LGG 0.008 high
ENSG00000115364 MRPL19 LUSC 0.014 low
ENSG00000115364 MRPL19 HNSC 0.0057 high
ENSG00000115364 MRPL19 READ 0.04 low
ENSG00000115364 MRPL19 KICH 0.0029 high
ENSG00000115364 MRPL19 LUAD 0.015 high
ENSG00000115364 MRPL19 PCPG 0.027 low
ENSG00000115364 MRPL19 COAD 0.0046 low
ENSG00000115364 MRPL19 OV 0.013 low
ENSG00000115364 MRPL19 PRAD 0.013 high
ENSG00000115364 MRPL19 GBM 0.023 low
ENSG00000115364 MRPL19 SKCM 0.041 low
ENSG00000115364 MRPL19 LIHC 0.029 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency