Ensembl ID ENSG00000114503 Gene ID 22916 Accession 7659
Gene Symbol NCBP2 Alias CBC2;NIP1;CBP20;PIG55 Full Name nuclear cap binding protein subunit 2
Position 3 : 196935406 - 196942594 Length 7189 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

ENSG00000114503 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000114503 NCBP2 0.81 2.00e-25 HNSC
ENSG00000114503 NCBP2 0.46 2.58e-27 BRCA
ENSG00000114503 NCBP2 0.63 1.58e-15 COAD
ENSG00000114503 NCBP2 1.36 8.94e-55 LUSC
ENSG00000114503 NCBP2 0.63 1.02e-12 STAD
ENSG00000114503 NCBP2 0.45 1.74e-13 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000114503 NCBP2 Cancer 26808319
ENSG00000114503 NCBP2 cancer 28849055
ENSG00000114503 NCBP2 lung cancer 30250529
ENSG00000114503 NCBP2 cancer 30723174
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000114503 NCBP2 MESO 0.05 low
ENSG00000114503 NCBP2 SARC 0.0034 high
ENSG00000114503 NCBP2 STAD 0.039 low
ENSG00000114503 NCBP2 CHOL 0.018 low
ENSG00000114503 NCBP2 UVM 0.0044 low
ENSG00000114503 NCBP2 PAAD 0.00065 high
ENSG00000114503 NCBP2 UCEC 0.0024 high
ENSG00000114503 NCBP2 THCA 0.043 high
ENSG00000114503 NCBP2 ACC 0.0072 high
ENSG00000114503 NCBP2 LGG 0.041 low
ENSG00000114503 NCBP2 LUSC 0.021 low
ENSG00000114503 NCBP2 HNSC 0.00064 high
ENSG00000114503 NCBP2 KICH 0.00043 high
ENSG00000114503 NCBP2 LUAD 0.0078 high
ENSG00000114503 NCBP2 PCPG 0.047 high
ENSG00000114503 NCBP2 BRCA 0.032 high
ENSG00000114503 NCBP2 COAD 0.012 high
ENSG00000114503 NCBP2 OV 0.04 low
ENSG00000114503 NCBP2 KIRC 0.00022 high
ENSG00000114503 NCBP2 BLCA 0.0023 low
ENSG00000114503 NCBP2 LAML 0.0072 low
ENSG00000114503 NCBP2 SKCM 0.0015 low
ENSG00000114503 NCBP2 CESC 0.031 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000114503 NCBP2 LUAD Del 1.910623 0.066302 0.330840 0.263566
ENSG00000114503 NCBP2 LGG Del 4.325299 0.070488 0.520490 0.093567
ENSG00000114503 NCBP2 CESC Amp 27.921881 0.675335 1.073535 0.752542
ENSG00000114503 NCBP2 SARC Del 0.809880 0.123852 0.494044 0.202335
ENSG00000114503 NCBP2 GBM Amp 0.934333 0.071930 0.434429 0.138648
ENSG00000114503 NCBP2 GBM Del 3.006199 0.076742 0.480420 0.100520
ENSG00000114503 NCBP2 HNSC Amp 41.177978 0.615860 0.779481 0.716475
ENSG00000114503 NCBP2 PCPG Del 3.076290 0.103587 0.635101 0.586420
ENSG00000114503 NCBP2 TGCT Amp 0.658729 0.114148 0.427058 0.293333
ENSG00000114503 NCBP2 DLBC Amp 2.314444 0.360896 0.811921 0.312500
ENSG00000114503 NCBP2 STAD Amp 4.719108 0.231600 0.489955 0.340136
ENSG00000114503 NCBP2 PRAD Del 0.751084 0.072617 0.456371 0.069106
ENSG00000114503 NCBP2 KIRC Amp 1.802912 0.045776 0.389691 0.159091