Ensembl ID ENSG00000113810 Gene ID 10051 Accession 14013
Gene Symbol SMC4 Alias CAPC;CAP-C;SMC-4;SMC4L1 Full Name structural maintenance of chromosomes 4
Position 3 : 160399274 - 160434953 Length 35680 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene belongs to the 'structural maintenance of chromosomes' (SMC) gene family. Members of this gene family play a role in two changes in chromosome structure during mitotic segregation of chromosomes- chromosome condensation and sister chromatid cohesion. The protein encoded by this gene is likely a subunit of the 13S condensin complex, which is involved in chromosome condensation. A pseudogene related to this gene is located on chromosome 2. [provided by RefSeq, Jun 2016]

ENSG00000113810 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000113810 SMC4 0.61 7.00e-14 KIRC
ENSG00000113810 SMC4 1.50 9.43e-60 BRCA
ENSG00000113810 SMC4 1.60 3.89e-51 LUSC
ENSG00000113810 SMC4 2.36 1.81e-12 GBM
ENSG00000113810 SMC4 1.25 2.91e-13 LIHC
ENSG00000113810 SMC4 1.66 6.97e-20 UCEC
ENSG00000113810 SMC4 3.94 5.65e-15 CESC
ENSG00000113810 SMC4 0.77 7.75e-12 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000113810 SMC4 tumor 17488335
ENSG00000113810 SMC4 breast cancer 21774228
ENSG00000113810 SMC4 cancer 22606281
ENSG00000113810 SMC4 primary liver cancer 22842912
ENSG00000113810 SMC4 tumor 24980149
ENSG00000113810 SMC4 colorectal cancer 25081869
ENSG00000113810 SMC4 colorectal cancer 25422241
ENSG00000113810 SMC4 prostate cancer 26631616
ENSG00000113810 SMC4 cancer 27687868
ENSG00000113810 SMC4 prostate cancer 27728977
ENSG00000113810 SMC4 cancer 28287612
ENSG00000113810 SMC4 tumors 28423514
ENSG00000113810 SMC4 AML 29043883
ENSG00000113810 SMC4 breast cancer 29402894
ENSG00000113810 SMC4 colorectal cancer 29467813
ENSG00000113810 SMC4 cancer 29949571
ENSG00000113810 SMC4 cancer 30202240
ENSG00000113810 SMC4 tumor 31394658
ENSG00000113810 SMC4 tumor 31516577
ENSG00000113810 SMC4 tumors 31611976
ENSG00000113810 SMC4 Breast Cancer 31871499
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000113810 SMC4 MESO 0.0012 high
ENSG00000113810 SMC4 SARC 0.007 high
ENSG00000113810 SMC4 STAD 0.032 low
ENSG00000113810 SMC4 UCEC 7e-04 high
ENSG00000113810 SMC4 LUSC 0.018 low
ENSG00000113810 SMC4 HNSC 0.0054 low
ENSG00000113810 SMC4 READ 0.035 low
ENSG00000113810 SMC4 LUAD 0.019 high
ENSG00000113810 SMC4 PCPG 0.006 high
ENSG00000113810 SMC4 THYM 0.0039 low
ENSG00000113810 SMC4 DLBC 0.046 low
ENSG00000113810 SMC4 KIRC 0.0054 high
ENSG00000113810 SMC4 PRAD 0.00028 high
ENSG00000113810 SMC4 BLCA 0.035 high
ENSG00000113810 SMC4 LAML 0.021 high
ENSG00000113810 SMC4 SKCM 0.00022 low
ENSG00000113810 SMC4 LIHC 0.00048 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000113810 SMC4 LUSC Amp 66.585036 1.055323 1.030577 0.850299
ENSG00000113810 SMC4 LUAD Amp 0.870131 0.121807 0.429011 0.269380
ENSG00000113810 SMC4 CESC Amp 16.602548 0.489478 0.997747 0.728814
ENSG00000113810 SMC4 ESCA Amp 10.787699 0.692957 0.866280 0.646739
ENSG00000113810 SMC4 HNSC Amp 27.653897 0.482224 0.743177 0.693487
ENSG00000113810 SMC4 PCPG Del 0.927646 0.063489 0.631584 0.580247
ENSG00000113810 SMC4 TGCT Amp 0.882927 0.126047 0.428502 0.306667
ENSG00000113810 SMC4 BRCA Amp 0.919712 0.150048 0.512313 0.279630
ENSG00000113810 SMC4 STAD Amp 2.483863 0.182008 0.497301 0.317460
ENSG00000113810 SMC4 PRAD Amp 1.245318 0.053911 0.425026 0.144309
ENSG00000113810 SMC4 UCEC Amp 6.214703 0.199566 0.672713 0.248609
ENSG00000113810 SMC4 KIRC Amp 0.857461 0.036840 0.385715 0.153409
ENSG00000113810 SMC4 OV Amp 30.296024 0.824903 0.896454 0.728843