Ensembl ID ENSG00000113810 Gene ID 10051 Accession 14013
Gene Symbol SMC4 Alias CAPC;CAP-C;SMC-4;SMC4L1 Full Name structural maintenance of chromosomes 4
Position 3 : 160399274 - 160434953 Length 35680 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene belongs to the 'structural maintenance of chromosomes' (SMC) gene family. Members of this gene family play a role in two changes in chromosome structure during mitotic segregation of chromosomes- chromosome condensation and sister chromatid cohesion. The protein encoded by this gene is likely a subunit of the 13S condensin complex, which is involved in chromosome condensation. A pseudogene related to this gene is located on chromosome 2. [provided by RefSeq, Jun 2016]

ENSG00000113810 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000113810 0.61 7.00e-14 KIRC
ENSG00000113810 1.50 9.43e-60 BRCA
ENSG00000113810 1.60 3.89e-51 LUSC
ENSG00000113810 2.36 1.81e-12 GBM
ENSG00000113810 1.25 2.91e-13 LIHC
ENSG00000113810 1.66 6.97e-20 UCEC
ENSG00000113810 3.94 5.65e-15 CESC
ENSG00000113810 0.77 7.75e-12 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000113810 tumor 17488335
ENSG00000113810 breast cancer 21774228
ENSG00000113810 cancer 22606281
ENSG00000113810 primary liver cancer 22842912
ENSG00000113810 tumor 24980149
ENSG00000113810 colorectal cancer 25081869
ENSG00000113810 colorectal cancer 25422241
ENSG00000113810 prostate cancer 26631616
ENSG00000113810 cancer 27687868
ENSG00000113810 prostate cancer 27728977
ENSG00000113810 cancer 28287612
ENSG00000113810 tumors 28423514
ENSG00000113810 AML 29043883
ENSG00000113810 breast cancer 29402894
ENSG00000113810 colorectal cancer 29467813
ENSG00000113810 cancer 29949571
ENSG00000113810 cancer 30202240
ENSG00000113810 tumor 31394658
ENSG00000113810 tumor 31516577
ENSG00000113810 tumors 31611976
ENSG00000113810 Breast Cancer 31871499
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000113810 MESO 0.0012 high
ENSG00000113810 SARC 0.007 high
ENSG00000113810 STAD 0.032 low
ENSG00000113810 UCEC 7e-04 high
ENSG00000113810 LUSC 0.018 low
ENSG00000113810 HNSC 0.0054 low
ENSG00000113810 READ 0.035 low
ENSG00000113810 LUAD 0.019 high
ENSG00000113810 PCPG 0.006 high
ENSG00000113810 THYM 0.0039 low
ENSG00000113810 DLBC 0.046 low
ENSG00000113810 KIRC 0.0054 high
ENSG00000113810 PRAD 0.00028 high
ENSG00000113810 BLCA 0.035 high
ENSG00000113810 LAML 0.021 high
ENSG00000113810 SKCM 0.00022 low
ENSG00000113810 LIHC 0.00048 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000113810 LUSC Amp 66.585036 1.055323 1.030577 0.850299
ENSG00000113810 LUAD Amp 0.870131 0.121807 0.429011 0.269380
ENSG00000113810 CESC Amp 16.602548 0.489478 0.997747 0.728814
ENSG00000113810 ESCA Amp 10.787699 0.692957 0.866280 0.646739
ENSG00000113810 HNSC Amp 27.653897 0.482224 0.743177 0.693487
ENSG00000113810 PCPG Del 0.927646 0.063489 0.631584 0.580247
ENSG00000113810 TGCT Amp 0.882927 0.126047 0.428502 0.306667
ENSG00000113810 BRCA Amp 0.919712 0.150048 0.512313 0.279630
ENSG00000113810 STAD Amp 2.483863 0.182008 0.497301 0.317460
ENSG00000113810 PRAD Amp 1.245318 0.053911 0.425026 0.144309
ENSG00000113810 UCEC Amp 6.214703 0.199566 0.672713 0.248609
ENSG00000113810 KIRC Amp 0.857461 0.036840 0.385715 0.153409
ENSG00000113810 OV Amp 30.296024 0.824903 0.896454 0.728843