Ensembl ID ENSG00000113761 Gene ID 23567 Accession 16403
Gene Symbol ZNF346 Alias JAZ;Zfp346 Full Name zinc finger protein 346
Position 5 : 177022696 - 177081189 Length 58494 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. It plays a role in protecting neurons by inhibiting cell cycle re-entry via stimulation of p21 gene expression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015]

ENSG00000113761 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000113761 ZNF346 0.47 5.42e-11 LIHC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000113761 ZNF346 colorectal cancer 19828471
ENSG00000113761 ZNF346 tumor 21715977
ENSG00000113761 ZNF346 colorectal cancer 25875936
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000113761 ZNF346 UVM 0.037 low
ENSG00000113761 ZNF346 PAAD 0.00014 low
ENSG00000113761 ZNF346 THCA 0.032 high
ENSG00000113761 ZNF346 ACC 0.005 high
ENSG00000113761 ZNF346 LGG 0.0092 low
ENSG00000113761 ZNF346 READ 0.013 low
ENSG00000113761 ZNF346 KICH 0.011 high
ENSG00000113761 ZNF346 LUAD 0.0077 low
ENSG00000113761 ZNF346 PCPG 0.035 high
ENSG00000113761 ZNF346 BRCA 0.041 high
ENSG00000113761 ZNF346 COAD 0.044 low
ENSG00000113761 ZNF346 DLBC 0.037 high
ENSG00000113761 ZNF346 KIRC 0.00034 low
ENSG00000113761 ZNF346 BLCA 0.016 high
ENSG00000113761 ZNF346 LAML 0.047 high
ENSG00000113761 ZNF346 SKCM 0.015 low
ENSG00000113761 ZNF346 CESC 0.027 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000113761 ZNF346 LGG Del 2.785997 0.059092 0.400610 0.109162
ENSG00000113761 ZNF346 KIRP Amp 0.755584 0.054844 0.613859 0.125000
ENSG00000113761 ZNF346 ACC Amp 1.893417 0.472947 1.255511 0.700000
ENSG00000113761 ZNF346 SKCM Del 1.948901 0.085845 0.481555 0.299728
ENSG00000113761 ZNF346 HNSC Del 0.647861 0.053303 0.387289 0.381226
ENSG00000113761 ZNF346 LIHC Amp 1.902737 0.143801 0.556647 0.356757
ENSG00000113761 ZNF346 BLCA Del 2.303591 0.102693 0.401382 0.490196
ENSG00000113761 ZNF346 PRAD Amp 0.669308 0.044787 0.476374 0.050813
ENSG00000113761 ZNF346 KIRC Amp 59.631976 0.329710 0.552435 0.628788