Ensembl ID ENSG00000113368 Gene ID 4001 Accession 6637
Gene Symbol LMNB1 Alias LMN;ADLD;LMN2;LMNB;MCPH26 Full Name lamin B1
Position 5 : 126776623 - 126837020 Length 60398 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

ENSG00000113368 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000113368 1.34 2.62e-39 KIRC
ENSG00000113368 1.55 3.14e-14 BLCA
ENSG00000113368 2.45 1.94e-156 BRCA
ENSG00000113368 0.59 1.18e-11 COAD
ENSG00000113368 2.03 2.03e-89 LUSC
ENSG00000113368 3.41 1.33e-18 GBM
ENSG00000113368 1.17 7.46e-11 KIRP
ENSG00000113368 1.20 6.13e-15 LIHC
ENSG00000113368 1.21 3.35e-14 STAD
ENSG00000113368 2.69 8.94e-79 UCEC
ENSG00000113368 1.58 4.87e-12 ESCA
ENSG00000113368 3.70 7.20e-26 CESC
ENSG00000113368 1.86 1.08e-51 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000113368 colon cancers 10517909
ENSG00000113368 cancer 12534602
ENSG00000113368 gastrointestinal stromal tumors 15519565
ENSG00000113368 tumor 16170025
ENSG00000113368 tumor 18439918
ENSG00000113368 liver cancer 19522540
ENSG00000113368 tumor 20020065
ENSG00000113368 breast cancer 20204270
ENSG00000113368 ovarian cancer 21439080
ENSG00000113368 breast cancer 21627864
ENSG00000113368 tumor 22496421
ENSG00000113368 breast cancer 22888636
ENSG00000113368 colorectal cancer 23357361
ENSG00000113368 breast cancer 23506640
ENSG00000113368 pancreatic cancer 23857605
ENSG00000113368 cancer 23934658
ENSG00000113368 cancer 24199607
ENSG00000113368 breast cancer 24293108
ENSG00000113368 cancers 24380701
ENSG00000113368 colon cancer 24732130
ENSG00000113368 cancer 25535332
ENSG00000113368 cancer 25684010
ENSG00000113368 tumor 26469707
ENSG00000113368 tumor 26691328
ENSG00000113368 cancer 27449096
ENSG00000113368 pancreatic cancer 27503760
ENSG00000113368 Tumor 27713152
ENSG00000113368 cancer 27994771
ENSG00000113368 cancers 28098202
ENSG00000113368 Cancer 28697756
ENSG00000113368 tumours 28804121
ENSG00000113368 GBM 28969644
ENSG00000113368 colon cancer 29115590
ENSG00000113368 breast tumors 29378184
ENSG00000113368 cancer 29415520
ENSG00000113368 cancers 29417283
ENSG00000113368 childhood cancer 29742327
ENSG00000113368 cervical cancer 30394198
ENSG00000113368 tumor 30467522
ENSG00000113368 tumors 30499270
ENSG00000113368 cancer 30679435
ENSG00000113368 tumor 30699341
ENSG00000113368 tumors 30897324
ENSG00000113368 lung cancer 31015297
ENSG00000113368 cancer 31105744
ENSG00000113368 Colorectal cancer 31193009
ENSG00000113368 tumor 31306099
ENSG00000113368 GBM 31358880
ENSG00000113368 cancer 31402955
ENSG00000113368 cancer 31541995
ENSG00000113368 GBM 31754113
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000113368 MESO 0.0071 high
ENSG00000113368 SARC 0.00099 high
ENSG00000113368 STAD 0.012 low
ENSG00000113368 PAAD 0.00063 high
ENSG00000113368 UCEC 0.04 high
ENSG00000113368 THCA 0.015 high
ENSG00000113368 LUSC 0.016 low
ENSG00000113368 HNSC 0.0082 low
ENSG00000113368 READ 0.029 low
ENSG00000113368 LUAD 0.0044 high
ENSG00000113368 PCPG 0.0071 high
ENSG00000113368 THYM 0.0019 low
ENSG00000113368 ESCA 0.016 high
ENSG00000113368 PRAD 0.001 high
ENSG00000113368 LAML 0.00037 low
ENSG00000113368 CESC 0.037 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000113368 LUSC Del 1.214733 0.073257 0.400471 0.772455
ENSG00000113368 LAML Del 5.995668 0.087859 0.796630 0.083770
ENSG00000113368 LUAD Del 2.011615 0.067351 0.340624 0.395349
ENSG00000113368 ACC Amp 1.228562 0.318460 1.251464 0.677778
ENSG00000113368 COAD Del 4.343833 0.075858 0.409170 0.252772
ENSG00000113368 SKCM Del 1.148774 0.074045 0.480359 0.313351
ENSG00000113368 STAD Del 4.608827 0.105074 0.397922 0.344671
ENSG00000113368 KIRC Amp 40.888272 0.252321 0.537199 0.579545
ENSG00000113368 OV Del 4.990284 0.246448 0.572577 0.499136