Ensembl ID
ENSG00000112739
Gene ID
8899
Accession
17346
Gene Symbol
PRPF4B
Alias
PR4H;PRP4;PRP4H;PRP4K;Prp4B;dJ1013A10.1
Full Name
pre-mRNA processing factor 4B
Position
6 : 4021267 - 4064983
Length
43717 bases
Strand
Plus strand
Status
Confidence
Main interacting RNAs snRNA RBP type
Non-canonical_RBPs
Summary
Pre-mRNA splicing occurs in two sequential transesterification steps, and the protein encoded by this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich protein-specific kinases and cyclin-dependent kinases (CDKs). This protein is regarded as a CDK-like kinase (Clk) with homology to mitogen-activated protein kinases (MAPKs). [provided by RefSeq, Jul 2008]
ENSG00000112739 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000112739
PRPF4B
cancer
24003220
ENSG00000112739
PRPF4B
ovarian cancer
25602630
ENSG00000112739
PRPF4B
hepatocellular cancer
25868860
ENSG00000112739
PRPF4B
cancer
26098145
ENSG00000112739
PRPF4B
breast cancer
26712520
ENSG00000112739
PRPF4B
ovarian cancer
28892043
ENSG00000112739
PRPF4B
breast cancer
29695716
ENSG00000112739
PRPF4B
tumors
31278301
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000112739
PRPF4B
SARC
0.0011
high
show
ENSG00000112739
PRPF4B
THCA
0.01
high
show
ENSG00000112739
PRPF4B
ACC
0.028
high
show
ENSG00000112739
PRPF4B
LGG
0.034
high
show
ENSG00000112739
PRPF4B
LUSC
0.044
low
show
ENSG00000112739
PRPF4B
HNSC
0.0028
low
show
ENSG00000112739
PRPF4B
READ
0.011
low
show
ENSG00000112739
PRPF4B
KIRP
0.016
high
show
ENSG00000112739
PRPF4B
KICH
0.0058
high
show
ENSG00000112739
PRPF4B
LUAD
0.01
low
show
ENSG00000112739
PRPF4B
THYM
0.0047
low
show
ENSG00000112739
PRPF4B
COAD
0.038
low
show
ENSG00000112739
PRPF4B
OV
0.0027
low
show
ENSG00000112739
PRPF4B
KIRC
0.037
low
show
ENSG00000112739
PRPF4B
LAML
0.0041
low
show
ENSG00000112739
PRPF4B
GBM
0.0025
low
show
ENSG00000112739
PRPF4B
SKCM
0.0028
low
show
ENSG00000112739
PRPF4B
LIHC
6e-04
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000112739
PRPF4B
LUSC
Del
1.913223
0.082117
0.356437
0.261477
ENSG00000112739
PRPF4B
THYM
Del
1.199597
0.051052
0.403903
0.211382
ENSG00000112739
PRPF4B
SARC
Del
1.379796
0.141545
0.517093
0.319066
ENSG00000112739
PRPF4B
PAAD
Del
2.589133
0.080610
0.354548
0.402174
ENSG00000112739
PRPF4B
ESCA
Del
6.457451
0.224768
0.445787
0.342391
ENSG00000112739
PRPF4B
SKCM
Amp
6.017999
0.267376
0.757760
0.572207
ENSG00000112739
PRPF4B
HNSC
Del
0.642475
0.053303
0.362107
0.178161
ENSG00000112739
PRPF4B
LIHC
Amp
3.233582
0.172766
0.760787
0.416216
ENSG00000112739
PRPF4B
BLCA
Amp
1.740199
0.201526
0.476730
0.289216
ENSG00000112739
PRPF4B
BLCA
Del
1.331161
0.088098
0.377105
0.210784
ENSG00000112739
PRPF4B
BRCA
Del
4.140124
0.088015
0.437410
0.173148
ENSG00000112739
PRPF4B
STAD
Del
4.555516
0.104583
0.396248
0.190476
ENSG00000112739
PRPF4B
UCEC
Amp
0.658431
0.101586
0.556581
0.183673
ENSG00000112739
PRPF4B
UVM
Amp
3.966451
0.349455
1.179083
0.562500
ENSG00000112739
PRPF4B
OV
Amp
5.683054
0.465462
0.751836
0.474957
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