Ensembl ID ENSG00000112249 Gene ID 10973 Accession 18697
Gene Symbol ASCC3 Alias RNAH;HELIC1;ASC1p200 Full Name activating signal cointegrator 1 complex subunit 3
Position 6 : 100508194 - 100881372 Length 373179 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

ENSG00000112249 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000112249 ASCC3 0.68 8.35e-16 COAD
ENSG00000112249 ASCC3 0.57 1.71e-11 LUSC
ENSG00000112249 ASCC3 0.65 2.12e-14 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000112249 ASCC3 colorectal cancer 18619730
ENSG00000112249 ASCC3 cancer 22055184
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000112249 ASCC3 MESO 0.024 high
ENSG00000112249 ASCC3 SARC 0.0038 high
ENSG00000112249 ASCC3 UVM 0.00019 high
ENSG00000112249 ASCC3 PAAD 0.0082 high
ENSG00000112249 ASCC3 THCA 0.027 low
ENSG00000112249 ASCC3 HNSC 0.037 high
ENSG00000112249 ASCC3 READ 0.015 low
ENSG00000112249 ASCC3 KIRP 0.0098 high
ENSG00000112249 ASCC3 BRCA 0.022 high
ENSG00000112249 ASCC3 COAD 0.0068 low
ENSG00000112249 ASCC3 UCS 0.035 low
ENSG00000112249 ASCC3 KIRC 0.0013 low
ENSG00000112249 ASCC3 BLCA 0.012 high
ENSG00000112249 ASCC3 GBM 0.026 low
ENSG00000112249 ASCC3 SKCM 0.00035 low
ENSG00000112249 ASCC3 CESC 0.009 high
ENSG00000112249 ASCC3 LIHC 0.0017 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000112249 ASCC3 LUAD Del 2.014306 0.067351 0.374849 0.501938
ENSG00000112249 ASCC3 SARC Del 0.988575 0.130171 0.444480 0.284047
ENSG00000112249 ASCC3 ESCA Del 1.432350 0.117679 0.366184 0.277174
ENSG00000112249 ASCC3 SKCM Del 2.438645 0.092630 0.564497 0.561308
ENSG00000112249 ASCC3 LIHC Del 1.806786 0.083101 0.601885 0.329730
ENSG00000112249 ASCC3 DLBC Del 3.611938 0.284196 0.598820 0.395833
ENSG00000112249 ASCC3 BLCA Del 3.163455 0.113572 0.378710 0.450980
ENSG00000112249 ASCC3 BRCA Del 7.786225 0.105759 0.488221 0.328704
ENSG00000112249 ASCC3 STAD Del 2.713353 0.086907 0.391993 0.204082
ENSG00000112249 ASCC3 PRAD Del 44.151046 0.307851 0.548535 0.323171
ENSG00000112249 ASCC3 KIRC Del 0.746692 0.025016 0.440477 0.265152
ENSG00000112249 ASCC3 OV Del 0.908450 0.179507 0.608520 0.497409