Ensembl ID
ENSG00000111786
Gene ID
8683
Accession
10791
Gene Symbol
SRSF9
Alias
SFRS9;SRp30c
Full Name
serine and arginine rich splicing factor 9
Position
12 : 120461672 - 120495946
Length
34275 bases
Strand
Minus strand
Status
Confidence
Main interacting RNAs mRNA RBP type
Canonical_RBPs
Summary
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two pseudogenes, one on chromosome 15 and the other on chromosome 21, have been found for this gene. [provided by RefSeq, Sep 2010]
ENSG00000111786 Expression In 33 Tumors
Ensembl ID
Gene symbol
Log2 Foldchange
Pvaue
Cancer
ENSG00000111786
SRSF9
0.70
3.56e-55
BRCA
ENSG00000111786
SRSF9
0.95
8.05e-54
LUSC
ENSG00000111786
SRSF9
0.79
8.00e-13
UCEC
ENSG00000111786
SRSF9
0.49
1.12e-12
LUAD
Ensembl ID
Gene symbol
Cancer types
Pubmed ID
ENSG00000111786
SRSF9
ovarian cancer
17176074
ENSG00000111786
SRSF9
ovarian cancer
21210970
ENSG00000111786
SRSF9
Tumor
22178073
ENSG00000111786
SRSF9
cancer
23592547
ENSG00000111786
SRSF9
squamous cervical cancer
27244197
ENSG00000111786
SRSF9
cervical cancer
30565744
ENSG00000111786
SRSF9
tumors
31561558
Ensembl ID
Gene symbol
Disease/phenotype
Mutation type
Mutated / Total samples
Literature
Ensembl ID
Gene symbol
Cancer
P-value
Which worse
show
ENSG00000111786
SRSF9
MESO
0.00032
high
show
ENSG00000111786
SRSF9
SARC
0.0034
high
show
ENSG00000111786
SRSF9
STAD
0.033
low
show
ENSG00000111786
SRSF9
UCEC
0.0092
low
show
ENSG00000111786
SRSF9
ACC
0.00027
high
show
ENSG00000111786
SRSF9
LUSC
0.037
low
show
ENSG00000111786
SRSF9
HNSC
0.0016
high
show
ENSG00000111786
SRSF9
KIRP
0.035
high
show
ENSG00000111786
SRSF9
KICH
0.0033
high
show
ENSG00000111786
SRSF9
LUAD
0.0023
high
show
ENSG00000111786
SRSF9
THYM
0.0091
low
show
ENSG00000111786
SRSF9
BRCA
0.049
high
show
ENSG00000111786
SRSF9
UCS
0.027
low
show
ENSG00000111786
SRSF9
OV
0.025
low
show
ENSG00000111786
SRSF9
DLBC
0.034
low
show
ENSG00000111786
SRSF9
PRAD
0.046
high
show
ENSG00000111786
SRSF9
SKCM
0.012
high
show
Ensembl ID
Gene symbol
Cancer
CNV type
-log10(q-value)
G-score
average amplitude
frequency
ENSG00000111786
SRSF9
LUAD
Del
0.740529
0.051825
0.276680
0.240310
ENSG00000111786
SRSF9
PAAD
Del
1.192147
0.055898
0.345588
0.222826
ENSG00000111786
SRSF9
LIHC
Del
1.138709
0.072859
0.410081
0.132432
ENSG00000111786
SRSF9
BRCA
Del
3.059062
0.081800
0.372842
0.196296
ENSG00000111786
SRSF9
OV
Del
2.247959
0.206994
0.562687
0.312608
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