Ensembl ID ENSG00000111701 Gene ID 339 Accession 604
Gene Symbol APOBEC1 Alias APO1;BEDP;HEPR;CDAR1;APOBEC-1 Full Name apolipoprotein B mRNA editing enzyme catalytic subunit 1
Position 12 : 7649400 - 7665908 Length 16509 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2015]

ENSG00000111701 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000111701 APOBEC1 4.80 9.73e-13 LUSC
ENSG00000111701 APOBEC1 -3.0 3.59e-14 STAD
ENSG00000111701 APOBEC1 6.78 8.87e-34 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000111701 APOBEC1 tumor 16595896
ENSG00000111701 APOBEC1 cancer 16793368
ENSG00000111701 APOBEC1 cancer 23137041
ENSG00000111701 APOBEC1 tumor 25085003
ENSG00000111701 APOBEC1 cancer 25806564
ENSG00000111701 APOBEC1 breast cancers 26682542
ENSG00000111701 APOBEC1 tumor 27111033
ENSG00000111701 APOBEC1 ovarian cancer 27527602
ENSG00000111701 APOBEC1 TGCT 27582469
ENSG00000111701 APOBEC1 cancer 29346513
ENSG00000111701 APOBEC1 tumor 30619092
ENSG00000111701 APOBEC1 cancer 30759888
ENSG00000111701 APOBEC1 tumor 31348242
ENSG00000111701 APOBEC1 cancer 31726973
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000111701 APOBEC1 PAAD 0.0058 high
ENSG00000111701 APOBEC1 ACC 0.0011 high
ENSG00000111701 APOBEC1 LUSC 0.004 high
ENSG00000111701 APOBEC1 KIRP 0.025 high
ENSG00000111701 APOBEC1 KICH 0.043 high
ENSG00000111701 APOBEC1 LUAD 0.00073 high
ENSG00000111701 APOBEC1 COAD 0.048 low
ENSG00000111701 APOBEC1 LIHC 0.0029 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000111701 APOBEC1 LUAD Del 2.533123 0.072596 0.347835 0.251938
ENSG00000111701 APOBEC1 LGG Amp 6.784207 0.119367 0.725566 0.124756
ENSG00000111701 APOBEC1 PAAD Del 1.079421 0.054133 0.396373 0.146739
ENSG00000111701 APOBEC1 TGCT Amp 19.429963 0.635085 1.715970 0.973333
ENSG00000111701 APOBEC1 STAD Del 1.548592 0.072668 0.414547 0.170068
ENSG00000111701 APOBEC1 OV Amp 0.648767 0.324440 0.897558 0.528497