Ensembl ID ENSG00000111669 Gene ID 7167 Accession 12009
Gene Symbol TPI1 Alias TIM;TPI;TPID;HEL-S-49 Full Name triosephosphate isomerase 1
Position 12 : 6867119 - 6870948 Length 3830 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

ENSG00000111669 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000111669 TPI1 0.98 4.13e-43 KIRC
ENSG00000111669 TPI1 0.91 4.78e-36 BRCA
ENSG00000111669 TPI1 0.58 1.62e-11 KICH
ENSG00000111669 TPI1 1.72 3.24e-70 LUSC
ENSG00000111669 TPI1 1.74 3.20e-47 UCEC
ENSG00000111669 TPI1 1.10 4.57e-28 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000111669 TPI1 tumor 10049939
ENSG00000111669 TPI1 ovarian cancers 10074910
ENSG00000111669 TPI1 tumors 10213500
ENSG00000111669 TPI1 stomach cancer 10736423
ENSG00000111669 TPI1 tumors 10945018
ENSG00000111669 TPI1 tumors 11034068
ENSG00000111669 TPI1 Malignant tumors 11254220
ENSG00000111669 TPI1 Cancer 11562943
ENSG00000111669 TPI1 tumor 12045238
ENSG00000111669 TPI1 tumor 12051920
ENSG00000111669 TPI1 colon cancer 12644837
ENSG00000111669 TPI1 cancer 12792754
ENSG00000111669 TPI1 tumor 15010854
ENSG00000111669 TPI1 colon cancer 15140625
ENSG00000111669 TPI1 cancer 15571283
ENSG00000111669 TPI1 cancer 15711180
ENSG00000111669 TPI1 tumor 16010427
ENSG00000111669 TPI1 breast tumors 16048908
ENSG00000111669 TPI1 cancers 16170390
ENSG00000111669 TPI1 tumor 1639315
ENSG00000111669 TPI1 tumor 16646076
ENSG00000111669 TPI1 tumor 16714762
ENSG00000111669 TPI1 tumor 1673105
ENSG00000111669 TPI1 tumours 17179993
ENSG00000111669 TPI1 tumor 17334368
ENSG00000111669 TPI1 esophageal cancer 17884789
ENSG00000111669 TPI1 tumor 17988525
ENSG00000111669 TPI1 cancers 18261581
ENSG00000111669 TPI1 gastric cancer 18309519
ENSG00000111669 TPI1 gastric cancer 18922971
ENSG00000111669 TPI1 lung cancer 19116456
ENSG00000111669 TPI1 tumor 19309015
ENSG00000111669 TPI1 cancer of tongue 19407367
ENSG00000111669 TPI1 breast cancer 19582718
ENSG00000111669 TPI1 ovarian cancer 19951750
ENSG00000111669 TPI1 prostate cancer 20233700
ENSG00000111669 TPI1 tumors 20421638
ENSG00000111669 TPI1 cancer 20544786
ENSG00000111669 TPI1 colon cancer 20682647
ENSG00000111669 TPI1 tumors 20975849
ENSG00000111669 TPI1 DLBCL 21323512
ENSG00000111669 TPI1 tumours 21329656
ENSG00000111669 TPI1 cancer 21386840
ENSG00000111669 TPI1 tumors 21503584
ENSG00000111669 TPI1 tumor 22178656
ENSG00000111669 TPI1 tumours 22471501
ENSG00000111669 TPI1 Cancer 22492719
ENSG00000111669 TPI1 tumor 22506042
ENSG00000111669 TPI1 breast cancer 22622283
ENSG00000111669 TPI1 breast cancer 22664934
ENSG00000111669 TPI1 lung cancer 23042266
ENSG00000111669 TPI1 cancer 23137041
ENSG00000111669 TPI1 tumors 23193368
ENSG00000111669 TPI1 cancer 23216862
ENSG00000111669 TPI1 metastatic tumors 23504277
ENSG00000111669 TPI1 tumor 24338489
ENSG00000111669 TPI1 cancer 24598263
ENSG00000111669 TPI1 cancer 24625664
ENSG00000111669 TPI1 tumor 24668817
ENSG00000111669 TPI1 colon cancer 24940699
ENSG00000111669 TPI1 tumors 25050814
ENSG00000111669 TPI1 tumor 25118927
ENSG00000111669 TPI1 colorectal cancer 25206290
ENSG00000111669 TPI1 tumor 25230742
ENSG00000111669 TPI1 cancer 25243088
ENSG00000111669 TPI1 cancer 25243985
ENSG00000111669 TPI1 colorectal cancer 25812794
ENSG00000111669 TPI1 metastatic colorectal cancer 25900515
ENSG00000111669 TPI1 tumor 26677869
ENSG00000111669 TPI1 gastric cancer 26911362
ENSG00000111669 TPI1 tumors 26918279
ENSG00000111669 TPI1 cancer 27068940
ENSG00000111669 TPI1 tumor 27908734
ENSG00000111669 TPI1 gastric cancer 28489783
ENSG00000111669 TPI1 gastric cancer 28737830
ENSG00000111669 TPI1 metastatic colorectal cancer 28992563
ENSG00000111669 TPI1 cancer 29102082
ENSG00000111669 TPI1 colorectal cancer 29119052
ENSG00000111669 TPI1 Prostate Cancer 29123462
ENSG00000111669 TPI1 gastric cancer 29307852
ENSG00000111669 TPI1 colorectal cancer 29312810
ENSG00000111669 TPI1 breast cancer 29545863
ENSG00000111669 TPI1 tumor 29549725
ENSG00000111669 TPI1 tumor 29568368
ENSG00000111669 TPI1 tumor 29629840
ENSG00000111669 TPI1 tumours 29713062
ENSG00000111669 TPI1 tumor 29856481
ENSG00000111669 TPI1 tumor 2988563
ENSG00000111669 TPI1 tumor 30069931
ENSG00000111669 TPI1 metastatic colorectal cancer 30172759
ENSG00000111669 TPI1 Tumor 30257515
ENSG00000111669 TPI1 cancer 30276573
ENSG00000111669 TPI1 metastatic colorectal cancer 30350179
ENSG00000111669 TPI1 tumour 30361548
ENSG00000111669 TPI1 metastatic colorectal cancer 30445951
ENSG00000111669 TPI1 tumors 30873387
ENSG00000111669 TPI1 cancer 30906545
ENSG00000111669 TPI1 tumour 30916466
ENSG00000111669 TPI1 tumors 30967137
ENSG00000111669 TPI1 tumor 31090062
ENSG00000111669 TPI1 metastatic colorectal cancer 31138881
ENSG00000111669 TPI1 tumors 31293965
ENSG00000111669 TPI1 tumor 31423202
ENSG00000111669 TPI1 tumor 31461438
ENSG00000111669 TPI1 colorectal cancer 31551425
ENSG00000111669 TPI1 tumor 3664464
ENSG00000111669 TPI1 cancer 3894553
ENSG00000111669 TPI1 cancer 6366678
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000111669 TPI1 MESO 0.00077 high
ENSG00000111669 TPI1 SARC 0.0018 high
ENSG00000111669 TPI1 CHOL 0.029 high
ENSG00000111669 TPI1 UVM 0.0014 high
ENSG00000111669 TPI1 PAAD 0.026 high
ENSG00000111669 TPI1 UCEC 0.025 low
ENSG00000111669 TPI1 ACC 0.00025 high
ENSG00000111669 TPI1 LGG 0.0031 high
ENSG00000111669 TPI1 HNSC 0.0069 high
ENSG00000111669 TPI1 THYM 0.0089 high
ENSG00000111669 TPI1 COAD 0.024 high
ENSG00000111669 TPI1 UCS 0.012 high
ENSG00000111669 TPI1 ESCA 0.032 high
ENSG00000111669 TPI1 OV 0.0057 high
ENSG00000111669 TPI1 DLBC 0.0077 low
ENSG00000111669 TPI1 KIRC 0.037 low
ENSG00000111669 TPI1 BLCA 0.047 high
ENSG00000111669 TPI1 LAML 0.00021 high
ENSG00000111669 TPI1 SKCM 0.0031 high
ENSG00000111669 TPI1 CESC 0.011 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000111669 TPI1 LUAD Del 2.213581 0.069449 0.344930 0.248062
ENSG00000111669 TPI1 LGG Amp 10.310554 0.153786 0.778452 0.134503
ENSG00000111669 TPI1 PAAD Del 1.094191 0.054133 0.396373 0.146739