Ensembl ID ENSG00000111639 Gene ID 51258 Accession 14044
Gene Symbol MRPL51 Alias mL51;CDA09;MRP64;bMRP64;HSPC241 Full Name mitochondrial ribosomal protein L51
Position 12 : 6491886 - 6493841 Length 1956 bases Strand Minus strand
Status Confidence Main interacting RNAsrRNARBP type Canonical_RBPs
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 4p and 21q. [provided by RefSeq, Jul 2008]

ENSG00000111639 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000111639 MRPL51 0.75 4.29e-32 BRCA
ENSG00000111639 MRPL51 0.57 3.04e-12 KICH
ENSG00000111639 MRPL51 1.10 1.08e-34 LUSC
Ensembl ID Gene symbol Cancer types Pubmed ID
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000111639 MRPL51 MESO 0.0057 high
ENSG00000111639 MRPL51 UVM 0.00018 high
ENSG00000111639 MRPL51 UCEC 0.007 high
ENSG00000111639 MRPL51 LUSC 0.0043 low
ENSG00000111639 MRPL51 READ 0.013 high
ENSG00000111639 MRPL51 KICH 0.002 high
ENSG00000111639 MRPL51 PCPG 0.00011 low
ENSG00000111639 MRPL51 OV 0.011 low
ENSG00000111639 MRPL51 DLBC 0.049 low
ENSG00000111639 MRPL51 KIRC 0.015 high
ENSG00000111639 MRPL51 BLCA 0.045 low
ENSG00000111639 MRPL51 LAML 0.01 high
ENSG00000111639 MRPL51 GBM 0.036 low
ENSG00000111639 MRPL51 CESC 0.019 low
ENSG00000111639 MRPL51 LIHC 0.0052 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000111639 MRPL51 LUAD Del 2.498917 0.072177 0.347285 0.250000
ENSG00000111639 MRPL51 LGG Amp 10.782407 0.158133 0.792035 0.134503
ENSG00000111639 MRPL51 SARC Del 0.857184 0.125958 0.489808 0.315175
ENSG00000111639 MRPL51 PAAD Del 1.095104 0.054133 0.396373 0.146739
ENSG00000111639 MRPL51 PRAD Del 0.623494 0.070636 0.507756 0.150407
ENSG00000111639 MRPL51 OV Amp 2.032342 0.375312 0.908061 0.549223