Ensembl ID ENSG00000111605 Gene ID 11052 Accession 13871
Gene Symbol CPSF6 Alias CFIM;CFIM68;CFIM72;HPBRII-4;HPBRII-7 Full Name cleavage and polyadenylation specific factor 6
Position 12 : 69239569 - 69274358 Length 34790 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins. [provided by RefSeq, Jul 2008]

ENSG00000111605 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000111605 CPSF6 0.31 3.77e-18 BRCA
ENSG00000111605 CPSF6 0.48 1.51e-13 COAD
ENSG00000111605 CPSF6 0.77 7.02e-47 LUSC
ENSG00000111605 CPSF6 0.51 1.09e-16 LIHC
ENSG00000111605 CPSF6 0.73 2.33e-17 CHOL
ENSG00000111605 CPSF6 0.61 2.07e-23 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000111605 CPSF6 breast cancer 16280054
ENSG00000111605 CPSF6 cancer 18636107
ENSG00000111605 CPSF6 prostate cancer 25189356
ENSG00000111605 CPSF6 cancer 26853146
ENSG00000111605 CPSF6 tumor 28673861
ENSG00000111605 CPSF6 GBM 30705404
ENSG00000111605 CPSF6 AML 31709264
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000111605 CPSF6 MESO 0.026 high
ENSG00000111605 CPSF6 UCEC 0.036 high
ENSG00000111605 CPSF6 LGG 0.0015 low
ENSG00000111605 CPSF6 LUSC 0.044 low
ENSG00000111605 CPSF6 HNSC 0.047 high
ENSG00000111605 CPSF6 READ 0.0043 low
ENSG00000111605 CPSF6 KICH 0.02 high
ENSG00000111605 CPSF6 LUAD 0.026 high
ENSG00000111605 CPSF6 PCPG 0.0032 high
ENSG00000111605 CPSF6 THYM 0.0027 low
ENSG00000111605 CPSF6 UCS 0.033 low
ENSG00000111605 CPSF6 ESCA 0.019 high
ENSG00000111605 CPSF6 KIRC 0.0029 high
ENSG00000111605 CPSF6 PRAD 0.009 high
ENSG00000111605 CPSF6 LAML 0.0039 low
ENSG00000111605 CPSF6 GBM 0.041 low
ENSG00000111605 CPSF6 SKCM 0.00011 low
ENSG00000111605 CPSF6 CESC 0.042 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000111605 CPSF6 LUSC Amp 2.024744 0.236264 0.547917 0.353293
ENSG00000111605 CPSF6 LUAD Amp 14.820003 0.337107 0.665853 0.321705
ENSG00000111605 CPSF6 ACC Amp 1.248228 0.328211 1.207155 0.766667
ENSG00000111605 CPSF6 UCS Amp 0.799683 0.510581 0.919610 0.303571
ENSG00000111605 CPSF6 SARC Amp 40.098497 1.309698 1.910347 0.307393
ENSG00000111605 CPSF6 GBM Amp 18.445157 0.281625 1.395208 0.116118
ENSG00000111605 CPSF6 PAAD Amp 1.677439 0.114693 0.719556 0.146739
ENSG00000111605 CPSF6 ESCA Amp 5.464000 0.495185 0.935396 0.271739
ENSG00000111605 CPSF6 SKCM Amp 9.228162 0.341322 1.077529 0.160763
ENSG00000111605 CPSF6 HNSC Amp 9.712241 0.274002 0.809481 0.195402
ENSG00000111605 CPSF6 TGCT Amp 2.397247 0.195040 0.566469 0.660000
ENSG00000111605 CPSF6 BLCA Amp 23.144518 0.602842 1.104109 0.291667
ENSG00000111605 CPSF6 BRCA Amp 15.067445 0.309947 0.752850 0.254630
ENSG00000111605 CPSF6 STAD Amp 17.814324 0.444196 0.981411 0.244898