Ensembl ID ENSG00000111596 Gene ID 4848 Accession 7878
Gene Symbol CNOT2 Alias NOT2;CDC36;NOT2H;HSPC131;IDNADFS Full Name CCR4-NOT transcription complex subunit 2
Position 12 : 70243002 - 70354993 Length 111992 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]

ENSG00000111596 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000111596 CNOT2 0.34 1.86e-22 KIRC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000111596 CNOT2 Tumor 23583282
ENSG00000111596 CNOT2 breast cancer 25191340
ENSG00000111596 CNOT2 tumor 26807845
ENSG00000111596 CNOT2 breast cancer 29024811
ENSG00000111596 CNOT2 breast cancers 30692147
ENSG00000111596 CNOT2 Non-Small Cell Lung Cancers 31574980
ENSG00000111596 CNOT2 tumor 31817495
ENSG00000111596 CNOT2 lung cancer 31894259
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000111596 CNOT2 SARC 0.01 high
ENSG00000111596 CNOT2 PAAD 0.011 high
ENSG00000111596 CNOT2 UCEC 0.03 low
ENSG00000111596 CNOT2 THCA 0.023 low
ENSG00000111596 CNOT2 ACC 0.0079 high
ENSG00000111596 CNOT2 LGG 0.0053 high
ENSG00000111596 CNOT2 KICH 2e-04 high
ENSG00000111596 CNOT2 LUAD 0.038 high
ENSG00000111596 CNOT2 THYM 0.0014 low
ENSG00000111596 CNOT2 BRCA 0.027 high
ENSG00000111596 CNOT2 COAD 0.026 low
ENSG00000111596 CNOT2 OV 0.012 high
ENSG00000111596 CNOT2 KIRC 0.03 high
ENSG00000111596 CNOT2 PRAD 0.011 high
ENSG00000111596 CNOT2 TGCT 0.049 low
ENSG00000111596 CNOT2 LAML 0.0047 low
ENSG00000111596 CNOT2 LIHC 0.00019 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000111596 CNOT2 LUSC Amp 1.971003 0.234664 0.525986 0.353293
ENSG00000111596 CNOT2 LUAD Amp 8.974921 0.262261 0.600474 0.306202
ENSG00000111596 CNOT2 ACC Amp 1.155613 0.304706 1.212183 0.755556
ENSG00000111596 CNOT2 UCS Amp 1.084949 0.557697 0.927171 0.321429
ENSG00000111596 CNOT2 SARC Amp 36.632547 1.241032 1.827006 0.307393
ENSG00000111596 CNOT2 GBM Amp 8.733361 0.179809 1.201030 0.100520
ENSG00000111596 CNOT2 PAAD Amp 1.677439 0.114693 0.695018 0.152174
ENSG00000111596 CNOT2 ESCA Amp 2.481356 0.362519 0.755860 0.266304
ENSG00000111596 CNOT2 SKCM Amp 6.375123 0.276942 0.961619 0.155313
ENSG00000111596 CNOT2 HNSC Amp 6.684901 0.229855 0.714032 0.195402
ENSG00000111596 CNOT2 TGCT Amp 3.115907 0.223453 0.578228 0.666667
ENSG00000111596 CNOT2 BLCA Amp 9.433332 0.379579 0.861307 0.269608
ENSG00000111596 CNOT2 BRCA Amp 11.353106 0.277490 0.713352 0.250000
ENSG00000111596 CNOT2 STAD Amp 11.295487 0.348519 0.828170 0.238095