Ensembl ID ENSG00000111331 Gene ID 4940 Accession 8088
Gene Symbol OAS3 Alias p100;p100OAS Full Name 2'-5'-oligoadenylate synthetase 3
Position 12 : 112938051 - 112976460 Length 38410 bases Strand Plus strand
Status Confidence Main interacting RNAsncRNARBP type Canonical_RBPs
Summary This gene encodes an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance. [provided by RefSeq, Jul 2008]

ENSG00000111331 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000111331 OAS3 0.97 8.00e-26 KIRC
ENSG00000111331 OAS3 1.55 1.19e-17 HNSC
ENSG00000111331 OAS3 1.54 9.51e-42 BRCA
ENSG00000111331 OAS3 1.19 7.34e-12 STAD
ENSG00000111331 OAS3 1.83 1.12e-17 UCEC
ENSG00000111331 OAS3 0.84 6.58e-11 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000111331 OAS3 cancer 20084279
ENSG00000111331 OAS3 cancer 25653161
ENSG00000111331 OAS3 cervical cancer 30127996
ENSG00000111331 OAS3 tumor 30134903
ENSG00000111331 OAS3 tumor 30510550
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000111331 OAS3 MESO 0.0031 low
ENSG00000111331 OAS3 STAD 0.029 low
ENSG00000111331 OAS3 PAAD 0.00013 high
ENSG00000111331 OAS3 UCEC 0.0034 high
ENSG00000111331 OAS3 THCA 0.036 low
ENSG00000111331 OAS3 ACC 0.00021 high
ENSG00000111331 OAS3 LUSC 0.02 high
ENSG00000111331 OAS3 READ 0.027 low
ENSG00000111331 OAS3 KIRP 0.0053 high
ENSG00000111331 OAS3 KICH 0.014 high
ENSG00000111331 OAS3 THYM 0.0053 high
ENSG00000111331 OAS3 COAD 0.024 low
ENSG00000111331 OAS3 OV 0.029 low
ENSG00000111331 OAS3 DLBC 0.04 high
ENSG00000111331 OAS3 KIRC 0.0058 low
ENSG00000111331 OAS3 TGCT 0.028 high
ENSG00000111331 OAS3 BLCA 0.037 low
ENSG00000111331 OAS3 LAML 0.015 high
ENSG00000111331 OAS3 GBM 0.019 high
ENSG00000111331 OAS3 SKCM 0.01 low
ENSG00000111331 OAS3 LIHC 0.0021 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000111331 OAS3 CHOL Del 0.852100 0.219537 0.589045 0.222222
ENSG00000111331 OAS3 LUAD Del 0.629436 0.050146 0.277419 0.242248
ENSG00000111331 OAS3 PAAD Del 1.313562 0.058251 0.351339 0.222826
ENSG00000111331 OAS3 BRCA Del 2.963014 0.081199 0.380697 0.191667
ENSG00000111331 OAS3 UCEC Del 1.205201 0.054635 0.408074 0.107607
ENSG00000111331 OAS3 OV Del 2.993042 0.219148 0.563127 0.324698