Ensembl ID ENSG00000110958 Gene ID 10728 Accession 16049
Gene Symbol PTGES3 Alias P23;TEBP;cPGES Full Name prostaglandin E synthase 3
Position 12 : 56663343 - 56688408 Length 25066 bases Strand Minus strand
Status Confidence Main interacting RNAsncRNARBP type Non-canonical_RBPs
Summary This gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). This protein functions as a co-chaperone with heat shock protein 90 (HSP90), localizing to response elements in DNA and disrupting transcriptional activation complexes. Alternative splicing results in multiple transcript variants. There are multiple pseudogenes of this gene on several different chromosomes. [provided by RefSeq, Feb 2016]

ENSG00000110958 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000110958 PTGES3 0.41 3.14e-19 BRCA
ENSG00000110958 PTGES3 0.73 7.87e-21 LUSC
ENSG00000110958 PTGES3 0.39 2.99e-11 LIHC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000110958 PTGES3 gastric cancer 14520691
ENSG00000110958 PTGES3 gastric cancer 17868774
ENSG00000110958 PTGES3 HNSCC 18642283
ENSG00000110958 PTGES3 tumor 19347995
ENSG00000110958 PTGES3 cancer 19412621
ENSG00000110958 PTGES3 tumors 19576239
ENSG00000110958 PTGES3 tumors 20048054
ENSG00000110958 PTGES3 tumor 20847343
ENSG00000110958 PTGES3 tumour 22075029
ENSG00000110958 PTGES3 cancers 24278769
ENSG00000110958 PTGES3 tumor 2454793
ENSG00000110958 PTGES3 cancer 24683251
ENSG00000110958 PTGES3 tumor 2479380
ENSG00000110958 PTGES3 tumor 25176350
ENSG00000110958 PTGES3 cancer 25367392
ENSG00000110958 PTGES3 tumors 26207152
ENSG00000110958 PTGES3 tumor 28081708
ENSG00000110958 PTGES3 tumor 2824547
ENSG00000110958 PTGES3 Tumor 29127155
ENSG00000110958 PTGES3 Tumour 29149404
ENSG00000110958 PTGES3 cancer 29545914
ENSG00000110958 PTGES3 tumor 31029168
ENSG00000110958 PTGES3 tumor 31451693
ENSG00000110958 PTGES3 tumors 31614548
ENSG00000110958 PTGES3 cancer 31750255
ENSG00000110958 PTGES3 tumour 7787881
ENSG00000110958 PTGES3 tumor 9426627
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000110958 PTGES3 MESO 0.00038 high
ENSG00000110958 PTGES3 SARC 0.029 high
ENSG00000110958 PTGES3 PAAD 0.023 high
ENSG00000110958 PTGES3 UCEC 0.019 high
ENSG00000110958 PTGES3 THCA 0.045 low
ENSG00000110958 PTGES3 ACC 0.0012 high
ENSG00000110958 PTGES3 HNSC 0.0033 high
ENSG00000110958 PTGES3 KICH 0.041 high
ENSG00000110958 PTGES3 COAD 0.0067 low
ENSG00000110958 PTGES3 UCS 0.024 low
ENSG00000110958 PTGES3 OV 0.00043 low
ENSG00000110958 PTGES3 PRAD 0.012 high
ENSG00000110958 PTGES3 SKCM 0.0052 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000110958 PTGES3 LUAD Amp 1.631289 0.141230 0.444459 0.308140
ENSG00000110958 PTGES3 ACC Amp 1.228562 0.323770 1.147016 0.766667
ENSG00000110958 PTGES3 GBM Amp 1.584010 0.083844 0.789639 0.100520
ENSG00000110958 PTGES3 SKCM Amp 0.757657 0.121323 0.619363 0.130790
ENSG00000110958 PTGES3 PCPG Amp 0.805519 0.072315 0.622754 0.092593