Ensembl ID ENSG00000110844 Gene ID 25766 Accession 25031
Gene Symbol PRPF40B Alias HYPC Full Name pre-mRNA processing factor 40 homolog B
Position 12 : 49568372 - 49644666 Length 76295 bases Strand Plus strand
Status Confidence Main interacting RNAssnRNARBP type Canonical_RBPs
Summary This gene encodes a WW-domain containing protein similar to yeast splicing factor PRP40. This protein has been shown to interact with Huntingtin and methyl CpG binding protein 2 (MeCP2). Alternative splicing results in different transcript variants. [provided by RefSeq, Aug 2014]

ENSG00000110844 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000110844 PRPF40B 0.71 3.74e-11 COAD
ENSG00000110844 PRPF40B 1.06 1.23e-32 LUSC
ENSG00000110844 PRPF40B 0.73 2.70e-12 LIHC
ENSG00000110844 PRPF40B 0.86 2.02e-20 LUAD
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000110844 PRPF40B AML 23645565
ENSG00000110844 PRPF40B pancreatic cancer 26498691
ENSG00000110844 PRPF40B cancer 31088860
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
ENSG00000110844 PRPF40B clear cell renal carcinoma missense_variant 0.3255% (4/1229) 1 entry
ENSG00000110844 PRPF40B skin melanoma frameshift_variant 1.034% (10/967) 2 entries
ENSG00000110844 PRPF40B colorectal adenocarcinoma frameshift_variant 3.691% (42/1138) 2 entries
ENSG00000110844 PRPF40B skin melanoma missense_variant 1.034% (10/967) 3 entries
ENSG00000110844 PRPF40B colorectal adenocarcinoma stop_gained 3.691% (42/1138) 1 entry
ENSG00000110844 PRPF40B brain glioblastoma missense_variant 0.6479% (6/926) 2 entries
ENSG00000110844 PRPF40B female breast carcinoma missense_variant 0.7491% (2/267) 1 entry
ENSG00000110844 PRPF40B lung adenocarcinoma missense_variant 0.8598% (10/1163) 4 entries
ENSG00000110844 PRPF40B colorectal adenocarcinoma sequence_alteration 3.691% (42/1138) 1 entry
ENSG00000110844 PRPF40B acute lymphoblastic leukemia missense_variant 0.6231% (2/321) 1 entry
ENSG00000110844 PRPF40B esophageal squamous cell carcinoma missense_variant 1.034% (7/677) 2 entries
ENSG00000110844 PRPF40B cecum adenocarcinoma frameshift_variant 3.2% (4/125) 1 entry
ENSG00000110844 PRPF40B breast carcinoma missense_variant 0.3544% (5/1411) 1 entry
ENSG00000110844 PRPF40B rectal adenocarcinoma missense_variant 1.357% (3/221) 1 entry
ENSG00000110844 PRPF40B melanoma frameshift_variant 7.921% (8/101) 1 entry
ENSG00000110844 PRPF40B large cell lung carcinoma missense_variant 11.11% (2/18) 1 entry
ENSG00000110844 PRPF40B colon adenocarcinoma frameshift_variant 2.493% (18/722) 2 entries
ENSG00000110844 PRPF40B acute myeloid leukemia missense_variant 0.339% (8/2360) 1 entry
ENSG00000110844 PRPF40B prostate carcinoma missense_variant 1.878% (8/426) 1 entry
ENSG00000110844 PRPF40B colon adenocarcinoma missense_variant 2.493% (18/722) 4 entries
ENSG00000110844 PRPF40B head and neck squamous cell carcinoma missense_variant 0.7987% (5/626) 1 entry
ENSG00000110844 PRPF40B prostate adenocarcinoma missense_variant 0.619% (9/1454) 3 entries
ENSG00000110844 PRPF40B esophageal adenocarcinoma missense_variant 1.142% (5/438) 1 entry
ENSG00000110844 PRPF40B colorectal adenocarcinoma missense_variant 3.691% (42/1138) 3 entries
ENSG00000110844 PRPF40B prostate carcinoma sequence_alteration 1.878% (8/426) 1 entry
ENSG00000110844 PRPF40B myelodysplastic syndrome missense_variant 0.8646% (6/694) 1 entry
ENSG00000110844 PRPF40B colon adenocarcinoma stop_gained 2.493% (18/722) 1 entry
ENSG00000110844 PRPF40B basal cell carcinoma missense_variant 3.448% (2/58) 1 entry
ENSG00000110844 PRPF40B lung adenocarcinoma frameshift_variant 0.8598% (10/1163) 1 entry
ENSG00000110844 PRPF40B pulmonary blastoma missense_variant 4.167% (1/24) 1 entry
ENSG00000110844 PRPF40B ovarian serous adenocarcinoma sequence_alteration 0.1486% (1/673) 1 entry
ENSG00000110844 PRPF40B gastric intestinal type adenocarcinoma frameshift_variant 2.353% (2/85) 1 entry
ENSG00000110844 PRPF40B pancreatic ductal adenocarcinoma missense_variant 0.4766% (6/1259) 1 entry
ENSG00000110844 PRPF40B ovarian serous adenocarcinoma missense_variant 0.1486% (1/673) 1 entry
ENSG00000110844 PRPF40B non-small cell lung carcinoma stop_gained 1.887% (1/53) 1 entry
ENSG00000110844 PRPF40B esophageal squamous cell carcinoma stop_gained 1.034% (7/677) 1 entry
ENSG00000110844 PRPF40B hemangioblastoma sequence_alteration 6.25% (2/32) 1 entry
ENSG00000110844 PRPF40B small cell lung carcinoma missense_variant 0.6289% (2/318) 1 entry
ENSG00000110844 PRPF40B T-cell acute lymphoblastic leukemia missense_variant 0.2169% (1/461) 1 entry
ENSG00000110844 PRPF40B colon adenocarcinoma sequence_alteration 2.493% (18/722) 1 entry
ENSG00000110844 PRPF40B primary peritoneal carcinoma (disease) missense_variant 100.0% (1/1) 1 entry
ENSG00000110844 PRPF40B colon carcinoma stop_gained 12.5% (1/8) 1 entry
ENSG00000110844 PRPF40B anaplastic oligoastrocytoma missense_variant 7.692% (1/13) 1 entry
ENSG00000110844 PRPF40B gastric intestinal type adenocarcinoma missense_variant 2.353% (2/85) 1 entry
ENSG00000110844 PRPF40B brain glioblastoma frameshift_variant 0.6479% (6/926) 1 entry
ENSG00000110844 PRPF40B lung adenocarcinoma sequence_alteration 0.8598% (10/1163) 1 entry
ENSG00000110844 PRPF40B small cell lung carcinoma stop_gained 0.6289% (2/318) 1 entry
ENSG00000110844 PRPF40B colorectal adenocarcinoma conservative_inframe_deletion 3.691% (42/1138) 1 entry
ENSG00000110844 PRPF40B melanoma conservative_inframe_deletion 7.921% (8/101) 1 entry
ENSG00000110844 PRPF40B oral squamous cell carcinoma missense_variant 0.4854% (1/206) 1 entry
ENSG00000110844 PRPF40B neoplasm of mature B-cells missense_variant 2.941% (1/34) 1 entry
ENSG00000110844 PRPF40B hemangioblastoma missense_variant 6.25% (2/32) 1 entry
ENSG00000110844 PRPF40B acute myeloid leukemia stop_gained 0.339% (8/2360) 1 entry
ENSG00000110844 PRPF40B osteosarcoma sequence_alteration 0.8621% (1/116) 1 entry
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000110844 PRPF40B STAD 0.016 high
ENSG00000110844 PRPF40B PAAD 0.003 low
ENSG00000110844 PRPF40B UCEC 0.011 high
ENSG00000110844 PRPF40B ACC 0.026 low
ENSG00000110844 PRPF40B LGG 0.017 low
ENSG00000110844 PRPF40B READ 0.021 high
ENSG00000110844 PRPF40B KICH 0.004 low
ENSG00000110844 PRPF40B LUAD 0.018 low
ENSG00000110844 PRPF40B PCPG 0.0048 high
ENSG00000110844 PRPF40B THYM 0.0015 high
ENSG00000110844 PRPF40B COAD 0.015 high
ENSG00000110844 PRPF40B ESCA 0.016 low
ENSG00000110844 PRPF40B DLBC 0.05 high
ENSG00000110844 PRPF40B BLCA 0.022 low
ENSG00000110844 PRPF40B LAML 0.0032 low
ENSG00000110844 PRPF40B CESC 0.022 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000110844 PRPF40B LGG Del 0.614530 0.037777 0.431822 0.132554
ENSG00000110844 PRPF40B PAAD Del 0.927232 0.050602 0.381066 0.179348