Ensembl ID ENSG00000110367 Gene ID 1656 Accession 2747
Gene Symbol DDX6 Alias P54;RCK;HLR2;IDDILF;Rck/p54 Full Name DEAD-box helicase 6
Position 11 : 118747763 - 118791164 Length 43402 bases Strand Minus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Mar 2012]

ENSG00000110367 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000110367 tumors 10319407
ENSG00000110367 cancer 19075689
ENSG00000110367 cancer 23932921
ENSG00000110367 colon cancer 26144048
ENSG00000110367 cancer 26610392
ENSG00000110367 tumor 26783102
ENSG00000110367 tumor 26980748
ENSG00000110367 cancer 27679741
ENSG00000110367 gastric cancer 28216671
ENSG00000110367 tumor 29262563
ENSG00000110367 gastric cancer 29314290
ENSG00000110367 Gastric Cancer 29987267
ENSG00000110367 Gastric Cancer 30959742
ENSG00000110367 cancer 31167132
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
ENSG00000110367 prostate adenocarcinoma sequence_alteration 1.307% (19/1454) 1 entry
ENSG00000110367 colon adenocarcinoma missense_variant 0.831% (6/722) 1 entry
ENSG00000110367 clear cell renal carcinoma sequence_alteration 0.2903% (4/1378) 1 entry
ENSG00000110367 Merkel cell skin cancer sequence_alteration 6.667% (2/30) 1 entry
ENSG00000110367 melanoma sequence_alteration 2.97% (3/101) 2 entries
ENSG00000110367 cecum adenocarcinoma sequence_alteration 4.0% (5/125) 1 entry
ENSG00000110367 gastric adenocarcinoma missense_variant 0.5376% (3/558) 1 entry
ENSG00000110367 lung adenocarcinoma missense_variant 0.4098% (5/1220) 2 entries
ENSG00000110367 small cell lung carcinoma sequence_alteration 0.6192% (2/323) 1 entry
ENSG00000110367 skin melanoma sequence_alteration 0.6205% (6/967) 1 entry
ENSG00000110367 chronic lymphocytic leukemia missense_variant 0.3378% (3/888) 1 entry
ENSG00000110367 brain glioblastoma missense_variant 0.8639% (8/926) 1 entry
ENSG00000110367 diffuse large B-cell lymphoma missense_variant 0.6557% (2/305) 1 entry
ENSG00000110367 cecum adenocarcinoma frameshift_variant 4.0% (5/125) 1 entry
ENSG00000110367 clear cell renal carcinoma missense_variant 0.2903% (4/1378) 1 entry
ENSG00000110367 gastric adenocarcinoma sequence_alteration 0.5376% (3/558) 1 entry
ENSG00000110367 brain glioblastoma sequence_alteration 0.8639% (8/926) 2 entries
ENSG00000110367 chronic lymphocytic leukemia sequence_alteration 0.3378% (3/888) 2 entries
ENSG00000110367 skin carcinoma sequence_alteration 4.808% (5/104) 1 entry
ENSG00000110367 colorectal adenocarcinoma missense_variant 1.494% (17/1138) 2 entries
ENSG00000110367 hemangioblastoma sequence_alteration 12.5% (4/32) 1 entry
ENSG00000110367 colon adenocarcinoma sequence_alteration 0.831% (6/722) 3 entries
ENSG00000110367 colorectal adenocarcinoma sequence_alteration 1.494% (17/1138) 2 entries
ENSG00000110367 prostate carcinoma sequence_alteration 2.273% (11/484) 2 entries
ENSG00000110367 skin melanoma missense_variant 0.6205% (6/967) 1 entry
ENSG00000110367 central nervous system primitive neuroectodermal neoplasm sequence_alteration 0.6757% (3/444) 1 entry
ENSG00000110367 lung adenocarcinoma sequence_alteration 0.4098% (5/1220) 1 entry
ENSG00000110367 colorectal adenocarcinoma frameshift_variant 1.494% (17/1138) 1 entry
ENSG00000110367 anaplastic oligodendroglioma missense_variant 2.381% (1/42) 1 entry
ENSG00000110367 Gallbladder Adenocarcinoma sequence_alteration 1.149% (1/87) 1 entry
ENSG00000110367 Thyroid Gland Oncocytic Follicular Carcinoma conservative_inframe_deletion 50.0% (1/2) 1 entry
ENSG00000110367 endometrial carcinoma sequence_alteration 4.348% (1/23) 1 entry
ENSG00000110367 central nervous system primitive neuroectodermal neoplasm missense_variant 0.6757% (3/444) 1 entry
ENSG00000110367 prostate adenocarcinoma missense_variant 1.307% (19/1454) 1 entry
ENSG00000110367 cecum adenocarcinoma missense_variant 4.0% (5/125) 1 entry
ENSG00000110367 prostate carcinoma missense_variant 2.273% (11/484) 1 entry
ENSG00000110367 endometrial carcinoma missense_variant 4.348% (1/23) 1 entry
ENSG00000110367 Pancreatic Acinar Cell Carcinoma sequence_alteration 5.0% (1/20) 1 entry
ENSG00000110367 ovarian serous adenocarcinoma missense_variant 0.1486% (1/673) 1 entry
ENSG00000110367 colorectal adenocarcinoma stop_gained 1.494% (17/1138) 1 entry
ENSG00000110367 nasopharyngeal squamous cell carcinoma sequence_alteration 0.5988% (1/167) 1 entry
ENSG00000110367 primary peritoneal carcinoma (disease) sequence_alteration 100.0% (1/1) 1 entry
ENSG00000110367 nasopharyngeal squamous cell carcinoma missense_variant 0.5988% (1/167) 1 entry
ENSG00000110367 ovarian serous adenocarcinoma sequence_alteration 0.1486% (1/673) 1 entry
ENSG00000110367 Thyroid Gland Oncocytic Follicular Carcinoma sequence_alteration 50.0% (1/2) 1 entry
ENSG00000110367 diffuse gastric adenocarcinoma sequence_alteration 1.266% (1/79) 1 entry
ENSG00000110367 small cell lung carcinoma stop_gained 0.6192% (2/323) 1 entry
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000110367 MESO 0.039 low
ENSG00000110367 STAD 0.0042 low
ENSG00000110367 CHOL 0.0099 low
ENSG00000110367 UVM 0.027 high
ENSG00000110367 UCEC 0.018 low
ENSG00000110367 HNSC 0.037 low
ENSG00000110367 READ 0.039 low
ENSG00000110367 KICH 0.022 high
ENSG00000110367 LUAD 0.027 low
ENSG00000110367 PCPG 0.012 high
ENSG00000110367 THYM 0.028 low
ENSG00000110367 UCS 0.013 low
ENSG00000110367 ESCA 0.014 low
ENSG00000110367 GBM 0.034 low
ENSG00000110367 CESC 0.044 high
ENSG00000110367 LIHC 0.0018 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000110367 LUSC Del 2.405715 0.087952 0.349323 0.347305
ENSG00000110367 LUAD Del 2.641751 0.073645 0.329720 0.213178
ENSG00000110367 LGG Amp 2.319035 0.067541 0.472161 0.167641
ENSG00000110367 CESC Del 27.435482 0.303509 0.576945 0.545763
ENSG00000110367 KIRP Del 4.225494 0.059019 0.587185 0.104167
ENSG00000110367 SARC Del 6.168065 0.236329 0.552309 0.466926
ENSG00000110367 ESCA Del 1.410083 0.117091 0.435334 0.413043
ENSG00000110367 SKCM Del 22.023136 0.252225 0.553017 0.550409
ENSG00000110367 HNSC Del 16.501983 0.154931 0.439300 0.467433
ENSG00000110367 LIHC Del 2.581826 0.093342 0.487324 0.251351
ENSG00000110367 PCPG Del 0.883794 0.062152 0.614542 0.283951
ENSG00000110367 TGCT Del 5.037471 0.140744 0.477357 0.806667
ENSG00000110367 BLCA Del 2.812167 0.109326 0.401825 0.370098
ENSG00000110367 BRCA Del 48.206798 0.222043 0.518318 0.492593
ENSG00000110367 STAD Del 1.083000 0.066285 0.361275 0.199546
ENSG00000110367 PRAD Del 1.581281 0.083399 0.496329 0.083333
ENSG00000110367 UCEC Del 0.668176 0.047002 0.481705 0.139147
ENSG00000110367 UVM Del 1.063142 0.071726 0.581446 0.075000