Ensembl ID ENSG00000109832 Gene ID 29118 Accession 18698
Gene Symbol DDX25 Alias GRTH Full Name DEAD-box helicase 25
Position 11 : 125903348 - 125943684 Length 40337 bases Strand Plus strand
Status Confidence Main interacting RNAsmRNARBP type Canonical_RBPs
Summary DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The encoded protein is a gonadotropin-regulated and developmentally expressed testicular RNA helicase. It may serve to maintain testicular functions related to steroidogenesis and spermatogenesis. [provided by RefSeq, Jul 2008]

ENSG00000109832 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000109832 DDX25 -2.4 3.81e-34 KIRC
ENSG00000109832 DDX25 -3.1 2.48e-16 KICH
ENSG00000109832 DDX25 4.34 4.11e-19 PCPG
ENSG00000109832 DDX25 -2.5 1.32e-16 KIRP
Ensembl ID Gene symbol Cancer types Pubmed ID
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000109832 DDX25 MESO 0.0017 low
ENSG00000109832 DDX25 UVM 0.0029 low
ENSG00000109832 DDX25 PAAD 0.00056 low
ENSG00000109832 DDX25 UCEC 0.0099 high
ENSG00000109832 DDX25 THCA 0.002 high
ENSG00000109832 DDX25 ACC 0.002 high
ENSG00000109832 DDX25 LUSC 0.022 low
ENSG00000109832 DDX25 HNSC 0.0082 low
ENSG00000109832 DDX25 KIRP 0.03 high
ENSG00000109832 DDX25 LUAD 0.0032 low
ENSG00000109832 DDX25 BRCA 0.0089 low
ENSG00000109832 DDX25 UCS 0.014 low
ENSG00000109832 DDX25 KIRC 0.0014 low
ENSG00000109832 DDX25 BLCA 0.013 low
ENSG00000109832 DDX25 GBM 0.026 high
ENSG00000109832 DDX25 SKCM 0.0047 high
ENSG00000109832 DDX25 CESC 0.0059 low
ENSG00000109832 DDX25 LIHC 0.034 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000109832 DDX25 LUSC Del 3.813579 0.102214 0.357144 0.351297
ENSG00000109832 DDX25 LUAD Del 4.662352 0.090431 0.345153 0.228682
ENSG00000109832 DDX25 LGG Amp 2.015856 0.063170 0.462211 0.167641
ENSG00000109832 DDX25 CESC Del 30.752875 0.325896 0.579646 0.549153
ENSG00000109832 DDX25 KIRP Del 3.140140 0.049621 0.562111 0.100694
ENSG00000109832 DDX25 SARC Del 8.690081 0.275086 0.563749 0.466926
ENSG00000109832 DDX25 ESCA Del 2.329840 0.141804 0.450466 0.429348
ENSG00000109832 DDX25 SKCM Del 23.301012 0.261075 0.555427 0.542234
ENSG00000109832 DDX25 HNSC Del 12.934689 0.137094 0.434538 0.454023
ENSG00000109832 DDX25 LIHC Del 2.577807 0.093342 0.483053 0.254054
ENSG00000109832 DDX25 TGCT Del 14.184413 0.270663 0.509275 0.813333
ENSG00000109832 DDX25 BLCA Del 2.849088 0.109857 0.408493 0.365196
ENSG00000109832 DDX25 BRCA Del 50.715870 0.228259 0.530065 0.487963
ENSG00000109832 DDX25 STAD Del 2.049332 0.079296 0.367902 0.204082
ENSG00000109832 DDX25 UCEC Del 3.856561 0.079943 0.530373 0.163265
ENSG00000109832 DDX25 UVM Del 1.063142 0.073079 0.580201 0.075000
ENSG00000109832 DDX25 OV Del 0.739922 0.175019 0.539925 0.326425