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| Ensembl ID | ENSG00000109819 | Gene ID | 10891 | Accession | 9237 |
| Gene Symbol | PPARGC1A | Alias | LEM6;PGC1;PGC1A;PGC-1v;PPARGC1;PGC-1alpha;PGC-1(alpha) | Full Name | PPARG coactivator 1 alpha |
| Position | 4 : 23792021 - 23890077 | Length | 98057 bases | Strand | Minus strand |
| Status | Confidence | Main interacting RNAs | N.A. | RBP type | Canonical_RBPs |
| Summary | The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008] | ||||
ENSG00000109819 Expression In 33 Tumors
| Ensembl ID | Gene symbol | Log2 Foldchange | Pvaue | Cancer |
|---|---|---|---|---|
| ENSG00000109819 | -1.7 | 3.88e-21 | KIRC | |
| ENSG00000109819 | -3.0 | 4.40e-26 | HNSC | |
| ENSG00000109819 | -1.7 | 1.21e-18 | COAD | |
| ENSG00000109819 | 1.53 | 3.22e-14 | KICH | |
| ENSG00000109819 | -1.7 | 4.63e-24 | PRAD |
| Ensembl ID | Gene symbol | Cancer types | Pubmed ID |
|---|---|---|---|
| ENSG00000109819 | tumour | 15920699 | |
| ENSG00000109819 | familial breast cancer | 16704985 | |
| ENSG00000109819 | tumour | 17047651 | |
| ENSG00000109819 | cancer | 17053067 | |
| ENSG00000109819 | colorectal tumor | 17341490 | |
| ENSG00000109819 | epithelial ovarian cancer | 17372612 | |
| ENSG00000109819 | Tumor | 17616713 | |
| ENSG00000109819 | cancer | 17678552 | |
| ENSG00000109819 | epithelial ovarian cancer | 17785072 | |
| ENSG00000109819 | liver cancer | 19102936 | |
| ENSG00000109819 | tumor | 19465495 | |
| ENSG00000109819 | cancer | 19602572 | |
| ENSG00000109819 | tumor | 19680556 | |
| ENSG00000109819 | tumours | 19755984 | |
| ENSG00000109819 | endometrial cancer | 19861117 | |
| ENSG00000109819 | prostate cancer | 19884383 | |
| ENSG00000109819 | tumour | 20211864 | |
| ENSG00000109819 | prostate cancer | 20477822 | |
| ENSG00000109819 | cancer | 21069263 | |
| ENSG00000109819 | breast cancer | 21128112 | |
| ENSG00000109819 | brain tumors | 21133850 | |
| ENSG00000109819 | tumors | 21162720 | |
| ENSG00000109819 | tumor | 21321201 | |
| ENSG00000109819 | tumor | 21339306 | |
| ENSG00000109819 | tumor | 21385932 | |
| ENSG00000109819 | intestinal cancer | 21467224 | |
| ENSG00000109819 | tumour | 21475674 | |
| ENSG00000109819 | colorectal cancer | 21862870 | |
| ENSG00000109819 | tumor | 21914785 | |
| ENSG00000109819 | breast cancer | 22050908 | |
| ENSG00000109819 | tumors | 22266114 | |
| ENSG00000109819 | cancer | 22285815 | |
| ENSG00000109819 | liver tumors | 22318941 | |
| ENSG00000109819 | tumor | 22428048 | |
| ENSG00000109819 | endometrial cancer | 22676897 | |
| ENSG00000109819 | breast cancer | 22703186 | |
| ENSG00000109819 | tumor | 22896732 | |
| ENSG00000109819 | tumor | 22897925 | |
| ENSG00000109819 | tumor | 23070475 | |
| ENSG00000109819 | kidney cancer | 23150719 | |
| ENSG00000109819 | tumor | 23166610 | |
| ENSG00000109819 | breast cancer | 23172368 | |
| ENSG00000109819 | cancer | 23216862 | |
| ENSG00000109819 | cancer | 23231082 | |
| ENSG00000109819 | tumour | 23335007 | |
| ENSG00000109819 | tumors | 23416000 | |
| ENSG00000109819 | liver cancer | 23564453 | |
| ENSG00000109819 | prostate cancer | 24186207 | |
| ENSG00000109819 | breast cancer | 24304688 | |
| ENSG00000109819 | cancer | 24350057 | |
| ENSG00000109819 | tumor | 24403067 | |
| ENSG00000109819 | benign tumors | 24472748 | |
| ENSG00000109819 | lung cancer | 24583643 | |
| ENSG00000109819 | cancer | 24595460 | |
| ENSG00000109819 | tumour | 24646150 | |
| ENSG00000109819 | tumor | 24812272 | |
| ENSG00000109819 | tumor | 24892905 | |
| ENSG00000109819 | Tumour | 24898700 | |
| ENSG00000109819 | breast cancer | 24904222 | |
| ENSG00000109819 | cancers | 24947365 | |
| ENSG00000109819 | pancreatic cancer | 25051362 | |
| ENSG00000109819 | tumor | 25141867 | |
| ENSG00000109819 | tumor | 25204433 | |
| ENSG00000109819 | breast cancer | 25212524 | |
| ENSG00000109819 | tumor | 25241037 | |
| ENSG00000109819 | tumour | 25243473 | |
| ENSG00000109819 | tumors | 25297634 | |
| ENSG00000109819 | Tumour | 25307264 | |
| ENSG00000109819 | cancers | 25490445 | |
| ENSG00000109819 | breast cancer | 25516445 | |
| ENSG00000109819 | tumor | 25522631 | |
| ENSG00000109819 | cancer | 25688484 | |
| ENSG00000109819 | tumor | 25736869 | |
| ENSG00000109819 | Colon Cancer | 25779952 | |
| ENSG00000109819 | tumors | 25791281 | |
| ENSG00000109819 | endometrial cancer | 25914546 | |
| ENSG00000109819 | cancers | 25918410 | |
| ENSG00000109819 | tumor | 26119730 | |
| ENSG00000109819 | cancer | 26136192 | |
| ENSG00000109819 | tumour | 26136413 | |
| ENSG00000109819 | cancer | 26334087 | |
| ENSG00000109819 | Pancreatic Cancer | 26365176 | |
| ENSG00000109819 | cancer | 26438876 | |
| ENSG00000109819 | liver cancer | 26442469 | |
| ENSG00000109819 | breast cancer | 26492917 | |
| ENSG00000109819 | tumor | 26636649 | |
| ENSG00000109819 | cancer | 26775698 | |
| ENSG00000109819 | Breast Cancer | 26804918 | |
| ENSG00000109819 | cancer | 26812134 | |
| ENSG00000109819 | breast cancer | 27010860 | |
| ENSG00000109819 | tumor | 27081083 | |
| ENSG00000109819 | tumor | 27086599 | |
| ENSG00000109819 | breast cancer | 27102200 | |
| ENSG00000109819 | tumors | 27134168 | |
| ENSG00000109819 | endometrial cancer | 27153547 | |
| ENSG00000109819 | Cancer | 27197257 | |
| ENSG00000109819 | tumours | 27214280 | |
| ENSG00000109819 | cancer | 27228792 | |
| ENSG00000109819 | prostate cancer | 27230528 | |
| ENSG00000109819 | primary cancer | 27308459 | |
| ENSG00000109819 | tumors | 27308473 | |
| ENSG00000109819 | endometrial cancer | 27418839 | |
| ENSG00000109819 | tumor | 27496732 | |
| ENSG00000109819 | colorectal cancer | 27531262 | |
| ENSG00000109819 | cancer | 27551487 | |
| ENSG00000109819 | cancer | 27563641 | |
| ENSG00000109819 | Cancer | 27589085 | |
| ENSG00000109819 | endometrial cancer | 27601924 | |
| ENSG00000109819 | tumor | 27626695 | |
| ENSG00000109819 | cancer | 27721378 | |
| ENSG00000109819 | tumors | 27726115 | |
| ENSG00000109819 | breast cancer | 27746856 | |
| ENSG00000109819 | benign breast tumor | 27780920 | |
| ENSG00000109819 | tumor | 27878239 | |
| ENSG00000109819 | breast cancer | 27916422 | |
| ENSG00000109819 | tumor | 27929420 | |
| ENSG00000109819 | colon cancer | 28007957 | |
| ENSG00000109819 | colorectal cancer | 28051997 | |
| ENSG00000109819 | tumor | 28076790 | |
| ENSG00000109819 | Prostate Cancer | 28093148 | |
| ENSG00000109819 | tumor | 28096382 | |
| ENSG00000109819 | tumor | 28250388 | |
| ENSG00000109819 | cancer | 28352611 | |
| ENSG00000109819 | breast cancer | 28357294 | |
| ENSG00000109819 | cancer | 28370295 | |
| ENSG00000109819 | tumor | 28381162 | |
| ENSG00000109819 | cancer | 28405929 | |
| ENSG00000109819 | tumors | 28423551 | |
| ENSG00000109819 | tumor | 28447025 | |
| ENSG00000109819 | prostate cancer | 28453464 | |
| ENSG00000109819 | tumor | 28473727 | |
| ENSG00000109819 | tumor | 28484465 | |
| ENSG00000109819 | breast cancer | 28525844 | |
| ENSG00000109819 | Cancer | 28596418 | |
| ENSG00000109819 | tumor | 28599408 | |
| ENSG00000109819 | cancer | 28620312 | |
| ENSG00000109819 | tumor | 28785374 | |
| ENSG00000109819 | lung cancer | 28803067 | |
| ENSG00000109819 | breast cancer | 28821609 | |
| ENSG00000109819 | tumor | 28825045 | |
| ENSG00000109819 | tumor | 28915557 | |
| ENSG00000109819 | tumor | 28932704 | |
| ENSG00000109819 | cancer | 28947972 | |
| ENSG00000109819 | tumors | 28978917 | |
| ENSG00000109819 | Breast Cancer | 28988825 | |
| ENSG00000109819 | tumor | 28991225 | |
| ENSG00000109819 | cancer | 29017115 | |
| ENSG00000109819 | tumor | 29038164 | |
| ENSG00000109819 | cancers | 29115599 | |
| ENSG00000109819 | colorectal cancer | 29121859 | |
| ENSG00000109819 | colorectal cancer | 29130104 | |
| ENSG00000109819 | Prostate Cancer | 29144947 | |
| ENSG00000109819 | ovarian cancer | 29163365 | |
| ENSG00000109819 | prostate cancer | 29181019 | |
| ENSG00000109819 | tumor | 29192176 | |
| ENSG00000109819 | breast cancer | 29200866 | |
| ENSG00000109819 | AML | 29229602 | |
| ENSG00000109819 | cancer | 29306792 | |
| ENSG00000109819 | tumor | 29323298 | |
| ENSG00000109819 | cancer | 29340100 | |
| ENSG00000109819 | cancer | 29354634 | |
| ENSG00000109819 | Cancer | 29361779 | |
| ENSG00000109819 | liver cancer | 29436167 | |
| ENSG00000109819 | tumor | 29453741 | |
| ENSG00000109819 | tumor | 29463573 | |
| ENSG00000109819 | tumor | 29511066 | |
| ENSG00000109819 | cancer | 29548774 | |
| ENSG00000109819 | colorectal cancer | 29566941 | |
| ENSG00000109819 | Cancer | 29599799 | |
| ENSG00000109819 | tumor | 29629336 | |
| ENSG00000109819 | cancer | 29654866 | |
| ENSG00000109819 | tumors | 29700317 | |
| ENSG00000109819 | cancer | 29717261 | |
| ENSG00000109819 | tumour | 29739810 | |
| ENSG00000109819 | tumor | 29740540 | |
| ENSG00000109819 | cancer | 29743249 | |
| ENSG00000109819 | tumor | 29785246 | |
| ENSG00000109819 | Colorectal Cancer | 29789344 | |
| ENSG00000109819 | cancer | 29865240 | |
| ENSG00000109819 | cancer | 29888964 | |
| ENSG00000109819 | cancer | 29915539 | |
| ENSG00000109819 | Breast Cancer | 29930100 | |
| ENSG00000109819 | tumor | 29966675 | |
| ENSG00000109819 | cancer | 30016403 | |
| ENSG00000109819 | prostate cancer | 30042415 | |
| ENSG00000109819 | tumor | 30054562 | |
| ENSG00000109819 | cancer | 30122956 | |
| ENSG00000109819 | tumor | 30143538 | |
| ENSG00000109819 | Breast Cancer | 30178342 | |
| ENSG00000109819 | cancer | 30186229 | |
| ENSG00000109819 | tumor | 30242145 | |
| ENSG00000109819 | tumors | 30244973 | |
| ENSG00000109819 | cancer | 30254608 | |
| ENSG00000109819 | tumors | 30310055 | |
| ENSG00000109819 | cancer | 30318520 | |
| ENSG00000109819 | tumor | 30374329 | |
| ENSG00000109819 | tumor | 30391585 | |
| ENSG00000109819 | cancer | 30400212 | |
| ENSG00000109819 | cancer | 30527740 | |
| ENSG00000109819 | tumor | 30578297 | |
| ENSG00000109819 | cancers | 30594485 | |
| ENSG00000109819 | tumor | 30610087 | |
| ENSG00000109819 | breast cancer | 30616060 | |
| ENSG00000109819 | tumour | 30648791 | |
| ENSG00000109819 | tumor | 30684287 | |
| ENSG00000109819 | primary cancer | 30691108 | |
| ENSG00000109819 | tumour | 30767037 | |
| ENSG00000109819 | cancer | 30771209 | |
| ENSG00000109819 | cancer | 30848477 | |
| ENSG00000109819 | tumor | 30867900 | |
| ENSG00000109819 | tumors | 30880247 | |
| ENSG00000109819 | cancer | 30906622 | |
| ENSG00000109819 | cancer | 30911677 | |
| ENSG00000109819 | cancer | 30920960 | |
| ENSG00000109819 | tumor | 30931098 | |
| ENSG00000109819 | cancer | 30936458 | |
| ENSG00000109819 | tumor | 30945396 | |
| ENSG00000109819 | Colorectal Cancer | 30959809 | |
| ENSG00000109819 | tumor | 30967773 | |
| ENSG00000109819 | tumor | 30997670 | |
| ENSG00000109819 | rectal cancer | 31028741 | |
| ENSG00000109819 | cancer | 31040369 | |
| ENSG00000109819 | breast cancer | 31052256 | |
| ENSG00000109819 | tumor | 31060333 | |
| ENSG00000109819 | Prostate Cancer | 31064849 | |
| ENSG00000109819 | tumor | 31066170 | |
| ENSG00000109819 | tumor | 31097683 | |
| ENSG00000109819 | breast cancer | 31154462 | |
| ENSG00000109819 | breast cancers | 31221959 | |
| ENSG00000109819 | colorectal cancer | 31258845 | |
| ENSG00000109819 | ovarian cancer | 31313989 | |
| ENSG00000109819 | thyroid cancer | 31333799 | |
| ENSG00000109819 | tumor | 31383001 | |
| ENSG00000109819 | tumor | 31451071 | |
| ENSG00000109819 | tumors | 31452510 | |
| ENSG00000109819 | tumor | 31469445 | |
| ENSG00000109819 | tumor | 31493764 | |
| ENSG00000109819 | Colorectal Cancer | 31519589 | |
| ENSG00000109819 | cancer | 31519688 | |
| ENSG00000109819 | tumor | 31547367 | |
| ENSG00000109819 | tumor | 31588240 | |
| ENSG00000109819 | Prostate Cancer | 31594836 | |
| ENSG00000109819 | cancer | 31600993 | |
| ENSG00000109819 | cancer | 31614775 | |
| ENSG00000109819 | liver cancer | 31623280 | |
| ENSG00000109819 | tumor | 31629659 | |
| ENSG00000109819 | ovarian cancer | 31657115 | |
| ENSG00000109819 | non-small cell lung cancer | 31663688 | |
| ENSG00000109819 | tumour | 31664147 | |
| ENSG00000109819 | tumor | 31694905 | |
| ENSG00000109819 | Malignant Tumours | 31702508 | |
| ENSG00000109819 | AML | 31709192 | |
| ENSG00000109819 | non-small-cell lung cancer | 31713888 | |
| ENSG00000109819 | tumor | 31926622 | |
| ENSG00000109819 | tumor | 31929186 | |
| ENSG00000109819 | tumor | 31968688 | |
| ENSG00000109819 | kidney cancer | 31982456 |
| Ensembl ID | Gene symbol | Disease/phenotype | Mutation type | Mutated / Total samples | Literature |
|---|
| Ensembl ID | Gene symbol | Cancer | P-value | Which worse | show |
|---|---|---|---|---|---|
| ENSG00000109819 | UVM | 0.01 | low | ||
| ENSG00000109819 | THCA | 0.00022 | high | ||
| ENSG00000109819 | LUAD | 0.025 | high | ||
| ENSG00000109819 | PCPG | 0.0079 | high | ||
| ENSG00000109819 | THYM | 0.011 | high | ||
| ENSG00000109819 | ESCA | 0.05 | low | ||
| ENSG00000109819 | DLBC | 0.015 | high | ||
| ENSG00000109819 | BLCA | 0.0034 | high | ||
| ENSG00000109819 | GBM | 0.02 | low | ||
| ENSG00000109819 | SKCM | 0.02 | high |
| Ensembl ID | Gene symbol | Cancer | CNV type | -log10(q-value) | G-score | average amplitude | frequency |
|---|