Ensembl ID ENSG00000109618 Gene ID 51091 Accession 30605
Gene Symbol SEPSECS Alias LP;SLA;SecS;PCH2D;SLA/LP;SLA-p35 Full Name Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
Position 4 : 25120014 - 25160550 Length 40537 bases Strand Minus strand
Status Confidence Main interacting RNAstRNARBP type Non-canonical_RBPs
Summary The amino acid selenocysteine is the only amino acid that does not have its own tRNA synthetase. Instead, this amino acid is synthesized on its cognate tRNA in a three step process. The protein encoded by this gene catalyzes the third step in the process, the conversion of O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec).[provided by RefSeq, Mar 2011]

ENSG00000109618 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000109618 SEPSECS -0.8 2.71e-15 KICH
ENSG00000109618 SEPSECS -0.8 1.75e-14 LIHC
ENSG00000109618 SEPSECS -1.8 1.44e-13 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000109618 SEPSECS tumor 29252180
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000109618 SEPSECS MESO 0.024 low
ENSG00000109618 SEPSECS SARC 0.028 low
ENSG00000109618 SEPSECS STAD 0.04 low
ENSG00000109618 SEPSECS UVM 0.043 high
ENSG00000109618 SEPSECS THCA 0.0035 high
ENSG00000109618 SEPSECS HNSC 0.0011 low
ENSG00000109618 SEPSECS LUAD 0.014 low
ENSG00000109618 SEPSECS PCPG 0.0013 high
ENSG00000109618 SEPSECS THYM 0.015 low
ENSG00000109618 SEPSECS COAD 0.018 high
ENSG00000109618 SEPSECS UCS 0.049 low
ENSG00000109618 SEPSECS DLBC 0.04 high
ENSG00000109618 SEPSECS PRAD 0.018 high
ENSG00000109618 SEPSECS BLCA 0.0094 low
ENSG00000109618 SEPSECS LAML 0.0027 low
ENSG00000109618 SEPSECS CESC 0.04 low
ENSG00000109618 SEPSECS LIHC 0.0017 low
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency